Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 1
2011 5
2012 2
2013 2
2014 2
2015 1
2019 1
2020 1
2021 1
2022 4
2023 2
2024 2
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

19 results

Results by year

Filters applied: . Clear all
Page 1
Engineered cytokine/antibody fusion proteins improve IL-2 delivery to pro-inflammatory cells and promote antitumor activity.
Leonard EK, Tomala J, Gould JR, Leff MI, Lin JX, Li P, Porter MJ, Johansen ER, Thompson L, Cao SD, Hou S, Henclova T, Huliciak M, Sargunas PR, Fabilane CS, Vaněk O, Kovar M, Schneider B, Raimondi G, Leonard WJ, Spangler JB. Leonard EK, et al. JCI Insight. 2024 Sep 24;9(18):e173469. doi: 10.1172/jci.insight.173469. JCI Insight. 2024. PMID: 39115939 Free PMC article.
Cytokine/Antibody Fusion Protein Design and Evaluation.
Fabilane CS, Stephenson AC, Leonard EK, VanDyke D, Spangler JB. Fabilane CS, et al. Among authors: leonard ek. Curr Protoc. 2024 May;4(5):e1061. doi: 10.1002/cpz1.1061. Curr Protoc. 2024. PMID: 38775006 Free PMC article.
Engineered antibody fusion proteins for targeted disease therapy.
Silver AB, Leonard EK, Gould JR, Spangler JB. Silver AB, et al. Among authors: leonard ek. Trends Pharmacol Sci. 2021 Dec;42(12):1064-1081. doi: 10.1016/j.tips.2021.09.009. Epub 2021 Oct 25. Trends Pharmacol Sci. 2021. PMID: 34706833 Free PMC article. Review.
Nanoparticle-based modulation of CD4+ T cell effector and helper functions enhances adoptive immunotherapy.
Isser A, Silver AB, Pruitt HC, Mass M, Elias EH, Aihara G, Kang SS, Bachmann N, Chen YY, Leonard EK, Bieler JG, Chaisawangwong W, Choy J, Shannon SR, Gerecht S, Weber JS, Spangler JB, Schneck JP. Isser A, et al. Among authors: leonard ek. Nat Commun. 2022 Oct 14;13(1):6086. doi: 10.1038/s41467-022-33597-y. Nat Commun. 2022. PMID: 36241639 Free PMC article.
IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function.
Casciola-Rosen L, Thiemann DR, Andrade F, Trejo-Zambrano MI, Leonard EK, Spangler JB, Skinner NE, Bailey J, Yegnasubramanian S, Wang R, Vaghasia AM, Gupta A, Cox AL, Ray SC, Linville RM, Guo Z, Searson PC, Machamer CE, Desiderio S, Sauer LM, Laeyendecker O, Garibaldi BT, Gao L, Damarla M, Hassoun PM, Hooper JE, Mecoli CA, Christopher-Stine L, Gutierrez-Alamillo L, Yang Q, Hines D, Clarke WA, Rothman RE, Pekosz A, Fenstermacher KZ, Wang Z, Zeger SL, Rosen A. Casciola-Rosen L, et al. Among authors: leonard ek. JCI Insight. 2022 May 9;7(9):e158362. doi: 10.1172/jci.insight.158362. JCI Insight. 2022. PMID: 35349483 Free PMC article.
Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity.
Leonard EK, Tomala J, Gould JR, Leff MI, Lin JX, Li P, Porter MJ, Johansen ER, Thompson L, Cao SD, Henclova T, Huliciak M, Vaněk O, Kovar M, Leonard WJ, Spangler JB. Leonard EK, et al. bioRxiv [Preprint]. 2023 May 4:2023.05.03.539272. doi: 10.1101/2023.05.03.539272. bioRxiv. 2023. Update in: JCI Insight. 2024 Sep 24;9(18):e173469. doi: 10.1172/jci.insight.173469. PMID: 37205604 Free PMC article. Updated. Preprint.
Design and validation of a corneal bioreactor.
Leonard EK, Pai VH, Amberg P, Gardner J, Orwin EJ. Leonard EK, et al. Biotechnol Bioeng. 2012 Dec;109(12):3189-98. doi: 10.1002/bit.24587. Epub 2012 Jul 18. Biotechnol Bioeng. 2012. PMID: 22729846
IgM autoantibodies recognizing ACE2 are associated with severe COVID-19.
Casciola-Rosen L, Thiemann DR, Andrade F, Trejo Zambrano MI, Hooper JE, Leonard EK, Spangler JB, Cox AL, Machamer CE, Sauer L, Laeyendecker O, Garibaldi BT, Ray SC, Mecoli CA, Christopher-Stine L, Gutierrez-Alamillo L, Yang Q, Hines D, Clarke WA, Rothman R, Pekosz A, Fenstermacher KJ, Wang Z, Zeger SL, Rosen A. Casciola-Rosen L, et al. Among authors: leonard ek. medRxiv [Preprint]. 2020 Oct 15:2020.10.13.20211664. doi: 10.1101/2020.10.13.20211664. medRxiv. 2020. Update in: JCI Insight. 2022 May 9;7(9):e158362. doi: 10.1172/jci.insight.158362. PMID: 33083808 Free PMC article. Updated. Preprint.
19 results