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Page 1
Genetic Determinants of Childhood Obesity.
Littleton SH, Berkowitz RI, Grant SFA. Littleton SH, et al. Mol Diagn Ther. 2020 Dec;24(6):653-663. doi: 10.1007/s40291-020-00496-1. Epub 2020 Oct 1. Mol Diagn Ther. 2020. PMID: 33006084 Free PMC article. Review.
Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2.
Littleton SH, Trang KB, Volpe CM, Cook K, DeBruyne N, Maguire JA, Weidekamp MA, Hodge KM, Boehm K, Lu S, Chesi A, Bradfield JP, Pippin JA, Anderson SA, Wells AD, Pahl MC, Grant SFA. Littleton SH, et al. Cell Genom. 2024 May 8;4(5):100556. doi: 10.1016/j.xgen.2024.100556. Epub 2024 May 1. Cell Genom. 2024. PMID: 38697123 Free PMC article.
Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus.
Burton EA, Argenziano M, Cook K, Ridler M, Lu S, Su C, Manduchi E, Littleton SH, Leonard ME, Hodge KM, Wang LS, Schellenberg GD, Johnson ME, Pahl MC, Pippin JA, Wells AD, Anderson SA, Brown CD, Grant SFA, Chesi A. Burton EA, et al. Among authors: littleton sh. bioRxiv [Preprint]. 2024 Aug 22:2024.08.22.609230. doi: 10.1101/2024.08.22.609230. bioRxiv. 2024. PMID: 39229212 Free PMC article. Preprint.
Perturbation of the insomnia WDR90 genome-wide association studies locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q.
Sonti S, Littleton SH, Pahl MC, Zimmerman AJ, Chesi A, Palermo J, Lasconi C, Brown EB, Pippin JA, Wells AD, Doldur-Balli F, Pack AI, Gehrman PR, Keene AC, Grant SFA. Sonti S, et al. Among authors: littleton sh. Sleep. 2024 Jul 11;47(7):zsae085. doi: 10.1093/sleep/zsae085. Sleep. 2024. PMID: 38571402 Free PMC article.
Metabolic links among milk, genes and gut.
Littleton SH, Grant SFA. Littleton SH, et al. Nat Metab. 2024 Jan;6(1):12-13. doi: 10.1038/s42255-023-00958-w. Nat Metab. 2024. PMID: 38253930 No abstract available.
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Trang KB, Pahl MC, Pippin JA, Su C, Littleton SH, Sharma P, Kulkarni NN, Ghanem LR, Terry NA, O'Brien JM, Wagley Y, Hankenson KD, Jermusyk A, Hoskins JW, Amundadottir LT, Xu M, Brown KM, Anderson SA, Yang W, Titchenell PM, Seale P, Cook L, Levings MK, Zemel BS, Chesi A, Wells AD, Grant SFA. Trang KB, et al. Among authors: littleton sh. medRxiv [Preprint]. 2024 Aug 13:2023.08.30.23294092. doi: 10.1101/2023.08.30.23294092. medRxiv. 2024. Update in: Elife. 2025 Jan 15;13:RP95411. doi: 10.7554/eLife.95411. PMID: 37693606 Free PMC article. Updated. Preprint.
Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2.
Littleton SH, Trang KB, Volpe CM, Cook K, DeBruyne N, Ann Maguire J, Ann Weidekamp M, Boehm K, Chesi A, Pippin JA, Anderson SA, Wells AD, Pahl MC, Grant SFA. Littleton SH, et al. bioRxiv [Preprint]. 2023 Aug 22:2023.08.21.553157. doi: 10.1101/2023.08.21.553157. bioRxiv. 2023. Update in: Cell Genom. 2024 May 8;4(5):100556. doi: 10.1016/j.xgen.2024.100556. PMID: 37662342 Free PMC article. Updated. Preprint.
Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q.
Sonti S, Littleton SH, Pahl MC, Zimmerman AJ, Chesi A, Palermo J, Lasconi C, Brown EB, Pippin JA, Wells AD, Doldur-Balli F, Pack AI, Gehrman PR, Keene AC, Grant SFA. Sonti S, et al. Among authors: littleton sh. bioRxiv [Preprint]. 2023 Aug 18:2023.08.17.553739. doi: 10.1101/2023.08.17.553739. bioRxiv. 2023. Update in: Sleep. 2024 Jul 11;47(7):zsae085. doi: 10.1093/sleep/zsae085. PMID: 37645863 Free PMC article. Updated. Preprint.
Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.
Pahl MC, Doege CA, Hodge KM, Littleton SH, Leonard ME, Lu S, Rausch R, Pippin JA, De Rosa MC, Basak A, Bradfield JP, Hammond RK, Boehm K, Berkowitz RI, Lasconi C, Su C, Chesi A, Johnson ME, Wells AD, Voight BF, Leibel RL, Cousminer DL, Grant SFA. Pahl MC, et al. Among authors: littleton sh. Nat Commun. 2021 Nov 19;12(1):6749. doi: 10.1038/s41467-021-27001-4. Nat Commun. 2021. PMID: 34799566 Free PMC article.
12 results