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34 results

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Page 1
Hyperbranched Vitrimer for Ultrahigh Energy Dissipation.
Cheng L, Zhao J, Xiong Z, Liu S, Yan X, Yu W. Cheng L, et al. Angew Chem Int Ed Engl. 2024 Apr 24:e202406937. doi: 10.1002/anie.202406937. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38656692
The ABn-type of macromonomers, the crosslinking points formed by the dynamic covalent connection via the associative exchange, and the weak yet dynamic exchange reaction are the three keys to developing high-performance HBV damping materials. We found that P(HMA-co-ViCL) 20k …
The ABn-type of macromonomers, the crosslinking points formed by the dynamic covalent connection via the associative exchange, and the weak …
Structural Exploration of Polycationic Nanoparticles for siRNA Delivery.
Yan Y, Zhang G, Wu C, Ren Q, Liu X, Huang F, Cao Y, Ye W. Yan Y, et al. ACS Biomater Sci Eng. 2022 May 9;8(5):1964-1974. doi: 10.1021/acsbiomaterials.2c00196. Epub 2022 Apr 5. ACS Biomater Sci Eng. 2022. PMID: 35380797
The optimal ratio varied for different combinations of cationic and hydrophobic segments. In particular, 20k PMB 0.5, PME 0.5, and PEB 1.0 showed >75% luciferase knockdown. ...Cellular uptake and endosomal escape experiments indicated that carboxybetaine modification of …
The optimal ratio varied for different combinations of cationic and hydrophobic segments. In particular, 20k PMB 0.5, PME 0.5, and PE …
Therapeutic Protein PEPylation: The Helix of Nonfouling Synthetic Polypeptides Minimizes Antidrug Antibody Generation.
Hou Y, Zhou Y, Wang H, Sun J, Wang R, Sheng K, Yuan J, Hu Y, Chao Y, Liu Z, Lu H. Hou Y, et al. ACS Cent Sci. 2019 Feb 27;5(2):229-236. doi: 10.1021/acscentsci.8b00548. Epub 2019 Jan 8. ACS Cent Sci. 2019. PMID: 30834311 Free PMC article.
Importantly, the unusual findings observed in the IFN series are reproduced in a human growth hormone (GH) conjugate series. Subcutaneously infused l(20K)-GH, GH modified with l-P(EG(3)Glu), evokes considerably less anti-GH and antipolymer antibodies compared to those modi …
Importantly, the unusual findings observed in the IFN series are reproduced in a human growth hormone (GH) conjugate series. Subcutaneously …
Sleep staging based on single-channel EEG and EOG with Tiny U-Net.
Lu J, Yan C, Li J, Liu C. Lu J, et al. Comput Biol Med. 2023 Sep;163:107127. doi: 10.1016/j.compbiomed.2023.107127. Epub 2023 Jun 7. Comput Biol Med. 2023. PMID: 37311382
Thus, to improve generalization, we select seven highly heterogeneous datasets covering 9970 records with over 20k hours among 7226 subjects spanning 950 days for training, validation, and evaluation. ...
Thus, to improve generalization, we select seven highly heterogeneous datasets covering 9970 records with over 20k hours among 7226 s …
Acid sphingomyelinase mediates the noise-induced liver disorder in mice.
Meng X, Gu Z, Xie X, Su Y, Zhang X, Ma H, Guo Y, Liu X, Cheng Y, Chang Y, Bao J. Meng X, et al. Clin Exp Pharmacol Physiol. 2019 Jun;46(6):556-566. doi: 10.1111/1440-1681.13083. Epub 2019 Apr 3. Clin Exp Pharmacol Physiol. 2019. PMID: 30854677
We aimed to investigate whether it mediated the noise elicited liver disorder on infrastructure, lipid metabolism, apoptosis, and oxidative stress. Mice were exposed to broad band noise (20-20k Hz, 90-110 dB) for 1, 3, 5 or 7 days by 3 hr/d. Doxepin hydrochloride (DOX), an …
We aimed to investigate whether it mediated the noise elicited liver disorder on infrastructure, lipid metabolism, apoptosis, and oxidative …
The role of carrier spectral composition in the perception of musical pitch.
Kuo CY, Liu JW, Wang CH, Juan CH, Hsieh IH. Kuo CY, et al. Atten Percept Psychophys. 2023 Aug;85(6):2083-2099. doi: 10.3758/s13414-023-02761-x. Epub 2023 Jul 21. Atten Percept Psychophys. 2023. PMID: 37479873
Findings suggest a perceptual enhancement of temporal envelope information with increasing carrier spectral region in musical pitch processing, at least for frequencies up to 6k Hz. For carriers in the extended high-frequency region (8-20k Hz), the use of temporal envelope …
Findings suggest a perceptual enhancement of temporal envelope information with increasing carrier spectral region in musical pitch processi …
Epistasis Activation Contributes Substantially to Heterosis in Temperate by Tropical Maize Hybrids.
Sang Z, Wang H, Yang Y, Zhang Z, Liu X, Li Z, Xu Y. Sang Z, et al. Front Plant Sci. 2022 Jul 11;13:921608. doi: 10.3389/fpls.2022.921608. eCollection 2022. Front Plant Sci. 2022. PMID: 35898210 Free PMC article.
Genome-wide prediction and association mapping was performed for grain weight per plant (GWPP) and days to silking (DTS) using 20K high-quality SNPs, showing that epistatic effects played a more prominent role than dominance effects in temperate by tropical maize hybrids. …
Genome-wide prediction and association mapping was performed for grain weight per plant (GWPP) and days to silking (DTS) using 20K hi …
Engineering a High-Affinity Anti-Methoxy Poly(ethylene glycol) (mPEG) Antibody for Sensitive Immunosensing of mPEGylated Therapeutics and mPEG Molecules.
Hsiao CY, Meng JL, Hong JZ, Ly XH, Lin MH, Chang CY, Nguyen MT, Cheng TL, Lin WW, Burnouf PA, Al-Qaisi TS, Liu ES, Su YC. Hsiao CY, et al. Bioconjug Chem. 2022 Nov 16;33(11):2180-2188. doi: 10.1021/acs.bioconjchem.2c00416. Epub 2022 Nov 1. Bioconjug Chem. 2022. PMID: 36320124
The affinity-enhanced h15-2Y antibody variant shows a 10.3-fold increase in mPEG-binding activity compared to parental h15-2b. h15-2Y-based sandwich ELISA can effectively quantify lmw mPEG(5K) and high-molecular-weight (hmw) mPEG(20K) at concentrations as low as 3.4 and 5. …
The affinity-enhanced h15-2Y antibody variant shows a 10.3-fold increase in mPEG-binding activity compared to parental h15-2b. h15-2Y-based …
34 results