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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1964 1
1974 1
1978 1
1980 2
1981 1
1985 3
1986 1
1988 4
1992 1
1993 1
1994 1
1996 2
1997 1
1998 6
1999 9
2000 10
2001 9
2002 5
2003 6
2004 4
2005 10
2006 5
2007 5
2008 4
2009 13
2010 7
2011 8
2012 5
2013 2
2014 11
2015 9
2016 5
2017 3
2018 1
2019 1
2020 1
2021 5
2022 1
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157 results
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Page 1
Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.
Germain DP, Hughes DA, Nicholls K, Bichet DG, Giugliani R, Wilcox WR, Feliciani C, Shankar SP, Ezgu F, Amartino H, Bratkovic D, Feldt-Rasmussen U, Nedd K, Sharaf El Din U, Lourenco CM, Banikazemi M, Charrow J, Dasouki M, Finegold D, Giraldo P, Goker-Alpan O, Longo N, Scott CR, Torra R, Tuffaha A, Jovanovic A, Waldek S, Packman S, Ludington E, Viereck C, Kirk J, Yu J, Benjamin ER, Johnson F, Lockhart DJ, Skuban N, Castelli J, Barth J, Barlow C, Schiffmann R. Germain DP, et al. Among authors: lockhart dj. N Engl J Med. 2016 Aug 11;375(6):545-55. doi: 10.1056/NEJMoa1510198. N Engl J Med. 2016. PMID: 27509102 Free article. Clinical Trial.
Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study.
Hughes DA, Nicholls K, Shankar SP, Sunder-Plassmann G, Koeller D, Nedd K, Vockley G, Hamazaki T, Lachmann R, Ohashi T, Olivotto I, Sakai N, Deegan P, Dimmock D, Eyskens F, Germain DP, Goker-Alpan O, Hachulla E, Jovanovic A, Lourenco CM, Narita I, Thomas M, Wilcox WR, Bichet DG, Schiffmann R, Ludington E, Viereck C, Kirk J, Yu J, Johnson F, Boudes P, Benjamin ER, Lockhart DJ, Barlow C, Skuban N, Castelli JP, Barth J, Feldt-Rasmussen U. Hughes DA, et al. Among authors: lockhart dj. J Med Genet. 2017 Apr;54(4):288-296. doi: 10.1136/jmedgenet-2016-104178. Epub 2016 Nov 10. J Med Genet. 2017. PMID: 27834756 Free PMC article. Clinical Trial.
A quantitative analysis of kinase inhibitor selectivity.
Karaman MW, Herrgard S, Treiber DK, Gallant P, Atteridge CE, Campbell BT, Chan KW, Ciceri P, Davis MI, Edeen PT, Faraoni R, Floyd M, Hunt JP, Lockhart DJ, Milanov ZV, Morrison MJ, Pallares G, Patel HK, Pritchard S, Wodicka LM, Zarrinkar PP. Karaman MW, et al. Among authors: lockhart dj. Nat Biotechnol. 2008 Jan;26(1):127-32. doi: 10.1038/nbt1358. Nat Biotechnol. 2008. PMID: 18183025
The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat.
Benjamin ER, Della Valle MC, Wu X, Katz E, Pruthi F, Bond S, Bronfin B, Williams H, Yu J, Bichet DG, Germain DP, Giugliani R, Hughes D, Schiffmann R, Wilcox WR, Desnick RJ, Kirk J, Barth J, Barlow C, Valenzano KJ, Castelli J, Lockhart DJ. Benjamin ER, et al. Among authors: lockhart dj. Genet Med. 2017 Apr;19(4):430-438. doi: 10.1038/gim.2016.122. Epub 2016 Sep 22. Genet Med. 2017. PMID: 27657681 Free PMC article.
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.
Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Liebundguth N, Lockhart DJ, Lucau-Danila A, Lussier M, M'Rabet N, Menard P, Mittmann M, Pai C, Rebischung C, Revuelta JL, Riles L, Roberts CJ, Ross-MacDonald P, Scherens B, Snyder M, Sookhai-Mahadeo S, Storms RK, Véronneau S, Voet M, Volckaert G, Ward TR, Wysocki R, Yen GS, Yu K, Zimmermann K, Philippsen P, Johnston M, Davis RW. Winzeler EA, et al. Among authors: lockhart dj. Science. 1999 Aug 6;285(5429):901-6. doi: 10.1126/science.285.5429.901. Science. 1999. PMID: 10436161
The citron homology domain as a scaffold for Rho1 signaling.
Bartual SG, Wei W, Zhou Y, Pravata VM, Fang W, Yan K, Ferenbach AT, Lockhart DEA, van Aalten DMF. Bartual SG, et al. Among authors: lockhart dea. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2110298118. doi: 10.1073/pnas.2110298118. Proc Natl Acad Sci U S A. 2021. PMID: 34544876 Free PMC article.
Functional genomics.
Fields S, Kohara Y, Lockhart DJ. Fields S, et al. Among authors: lockhart dj. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8825-6. doi: 10.1073/pnas.96.16.8825. Proc Natl Acad Sci U S A. 1999. PMID: 10430853 Free PMC article.
Targeting a critical step in fungal hexosamine biosynthesis.
Lockhart DEA, Stanley M, Raimi OG, Robinson DA, Boldovjakova D, Squair DR, Ferenbach AT, Fang W, van Aalten DMF. Lockhart DEA, et al. J Biol Chem. 2020 Jun 26;295(26):8678-8691. doi: 10.1074/jbc.RA120.012985. Epub 2020 Apr 27. J Biol Chem. 2020. PMID: 32341126 Free PMC article.
A review of dental implants and infection.
Pye AD, Lockhart DE, Dawson MP, Murray CA, Smith AJ. Pye AD, et al. Among authors: lockhart de. J Hosp Infect. 2009 Jun;72(2):104-10. doi: 10.1016/j.jhin.2009.02.010. Epub 2009 Mar 28. J Hosp Infect. 2009. PMID: 19329223 Review.
157 results