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Sirtuins regulate key aspects of lipid metabolism.
Lomb DJ, Laurent G, Haigis MC. Lomb DJ, et al. Biochim Biophys Acta. 2010 Aug;1804(8):1652-7. doi: 10.1016/j.bbapap.2009.11.021. Epub 2009 Dec 2. Biochim Biophys Acta. 2010. PMID: 19962456 Review.
Prolyl hydroxylase inhibitors depend on extracellular glucose and hypoxia-inducible factor (HIF)-2alpha to inhibit cell death caused by nerve growth factor (NGF) deprivation: evidence that HIF-2alpha has a role in NGF-promoted survival of sympathetic neurons.
Lomb DJ, Desouza LA, Franklin JL, Freeman RS. Lomb DJ, et al. Mol Pharmacol. 2009 May;75(5):1198-209. doi: 10.1124/mol.108.053157. Epub 2009 Feb 9. Mol Pharmacol. 2009. PMID: 19204094 Free PMC article.