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Page 1
Targeted Delivery of Immunomodulators to Lymph Nodes.
Azzi J, Yin Q, Uehara M, Ohori S, Tang L, Cai K, Ichimura T, McGrath M, Maarouf O, Kefaloyianni E, Loughhead S, Petr J, Sun Q, Kwon M, Tullius S, von Andrian UH, Cheng J, Abdi R. Azzi J, et al. Among authors: loughhead s. Cell Rep. 2016 May 10;15(6):1202-13. doi: 10.1016/j.celrep.2016.04.007. Epub 2016 Apr 28. Cell Rep. 2016. PMID: 27134176 Free PMC article.
Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.
Zemmour D, Pratama A, Loughhead SM, Mathis D, Benoist C. Zemmour D, et al. Among authors: loughhead sm. Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3472-E3480. doi: 10.1073/pnas.1700946114. Epub 2017 Apr 10. Proc Natl Acad Sci U S A. 2017. PMID: 28396406 Free PMC article.
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo.
DiTommaso T, Cole JM, Cassereau L, Buggé JA, Hanson JLS, Bridgen DT, Stokes BD, Loughhead SM, Beutel BA, Gilbert JB, Nussbaum K, Sorrentino A, Toggweiler J, Schmidt T, Gyuelveszi G, Bernstein H, Sharei A. DiTommaso T, et al. Among authors: loughhead sm. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10907-E10914. doi: 10.1073/pnas.1809671115. Epub 2018 Oct 31. Proc Natl Acad Sci U S A. 2018. PMID: 30381459 Free PMC article.
Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice.
Blagovic K, Smith CK, Ramakrishnan A, Moore L, Soto DR, Thompson Z, Stockmann AP, Kruszelnicki S, Thakkar A, Murray J, Torres S, Wondimagegnhu B, Yi R, Dadgar M, Paracha AM, Page C, Clear L, Chaudhry OA, Myint M, Bridgen DT, Gilbert JB, Seidl KJ, Sharei A, Loughhead S, Bernstein H, Yarar D. Blagovic K, et al. Among authors: loughhead s. Front Immunol. 2022 Oct 3;13:1015585. doi: 10.3389/fimmu.2022.1015585. eCollection 2022. Front Immunol. 2022. PMID: 36263022 Free PMC article.
Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity.
Booty MG, Hlavaty KA, Stockmann A, Ozay EI, Smith C, Tian L, How E, Subramanya D, Venkitaraman A, Yee C, Pryor O, Volk K, Blagovic K, Vicente-Suarez I, Yarar D, Myint M, Merino A, Chow J, Abdeljawad T, An H, Liu S, Mao S, Heimann M, Talarico L, Jacques MK, Chong E, Pomerance L, Gonzalez JT, von Andrian UH, Jensen KF, Langer R, Knoetgen H, Trumpfheller C, Umaña P, Bernstein H, Sharei A, Loughhead SM. Booty MG, et al. Among authors: loughhead sm. J Immunol. 2022 Feb 15;208(4):929-940. doi: 10.4049/jimmunol.2100656. Epub 2022 Jan 28. J Immunol. 2022. PMID: 35091434 Free PMC article.
Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors.
Jimeno A, Baranda J, Iams WT, Park JC, Mita M, Gordon MS, Taylor M, Dhani N, Leal AD, Neupane P, Eng C, Yeku O, Mita A, Moser JC, Butler M, Loughhead SM, Jennings J, Miselis NR, Ji RR, Nair N, Kornacker M, Zwirtes RF, Bernstein H, Sharei A. Jimeno A, et al. Among authors: loughhead sm. Invest New Drugs. 2023 Apr;41(2):284-295. doi: 10.1007/s10637-023-01342-x. Epub 2023 Mar 3. Invest New Drugs. 2023. PMID: 36867316 Free PMC article. Clinical Trial.
Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex.
Prüss H, Tedeschi A, Thiriot A, Lynch L, Loughhead SM, Stutte S, Mazo IB, Kopp MA, Brommer B, Blex C, Geurtz LC, Liebscher T, Niedeggen A, Dirnagl U, Bradke F, Volz MS, DeVivo MJ, Chen Y, von Andrian UH, Schwab JM. Prüss H, et al. Among authors: loughhead sm. Nat Neurosci. 2017 Nov;20(11):1549-1559. doi: 10.1038/nn.4643. Epub 2017 Sep 18. Nat Neurosci. 2017. PMID: 28920935
15 results