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Cytoplasmic cleavage of IMPA1 3' UTR is necessary for maintaining axon integrity.
Andreassi C, Luisier R, Crerar H, Darsinou M, Blokzijl-Franke S, Lenn T, Luscombe NM, Cuda G, Gaspari M, Saiardi A, Riccio A. Andreassi C, et al. Among authors: luisier r. Cell Rep. 2021 Feb 23;34(8):108778. doi: 10.1016/j.celrep.2021.108778. Cell Rep. 2021. PMID: 33626357 Free PMC article.
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Luisier R, et al. Nat Commun. 2018 May 22;9(1):2010. doi: 10.1038/s41467-018-04373-8. Nat Commun. 2018. PMID: 29789581 Free PMC article.
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