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1995 1
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2019 2
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Page 1
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Avet C, Mancini A, Breton B, Le Gouill C, Hauser AS, Normand C, Kobayashi H, Gross F, Hogue M, Lukasheva V, St-Onge S, Carrier M, Héroux M, Morissette S, Fauman EB, Fortin JP, Schann S, Leroy X, Gloriam DE, Bouvier M. Avet C, et al. Among authors: lukasheva v. Elife. 2022 Mar 18;11:e74101. doi: 10.7554/eLife.74101. Elife. 2022. PMID: 35302493 Free PMC article.
BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.
Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. Wright SC, et al. Among authors: lukasheva v. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2025846118. doi: 10.1073/pnas.2025846118. Proc Natl Acad Sci U S A. 2021. PMID: 33990469 Free PMC article.
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: lukasheva v. Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6. Nat Commun. 2019. PMID: 31501422 Free PMC article.
Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.
Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL. Ehrlich AT, et al. Among authors: lukasheva v. iScience. 2019 Apr 26;14:47-57. doi: 10.1016/j.isci.2019.03.011. Epub 2019 Mar 15. iScience. 2019. PMID: 30925410 Free PMC article.
Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.
Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL. Ehrlich AT, et al. Among authors: lukasheva v. Brain Struct Funct. 2018 Apr;223(3):1275-1296. doi: 10.1007/s00429-017-1547-3. Epub 2017 Nov 6. Brain Struct Funct. 2018. PMID: 29110094 Free PMC article.
Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR.
Lukasheva V, Devost D, Le Gouill C, Namkung Y, Martin RD, Longpré JM, Amraei M, Shinjo Y, Hogue M, Lagacé M, Breton B, Aoki J, Tanny JC, Laporte SA, Pineyro G, Inoue A, Bouvier M, Hébert TE. Lukasheva V, et al. Sci Rep. 2020 May 29;10(1):8779. doi: 10.1038/s41598-020-65636-3. Sci Rep. 2020. PMID: 32471984 Free PMC article.
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: lukasheva v. Nat Commun. 2020 Apr 16;11(1):1929. doi: 10.1038/s41467-020-15945-y. Nat Commun. 2020. PMID: 32300106 Free PMC article.
13 results