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Heterocyclic modulators of the NMDA receptor.
Pellicciari R, Natalini B, Costantino G, Garzon A, Luneia R, Mahmoud MR, Marinozzi M, Roberti M, Rosato GC, Shiba SA. Pellicciari R, et al. Among authors: luneia r. Farmaco. 1993 Feb;48(2):151-7. Farmaco. 1993. PMID: 8494596 Review.
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist.
Cozzi A, Attucci S, Peruginelli F, Marinozzi M, Luneia R, Pellicciari R, Moroni F. Cozzi A, et al. Among authors: luneia r. Eur J Neurosci. 1997 Jul;9(7):1350-5. doi: 10.1111/j.1460-9568.1997.tb01489.x. Eur J Neurosci. 1997. PMID: 9240392
Synthesis and pharmacological characterization of all sixteen stereoisomers of 2-(2'-carboxy-3'-phenylcyclopropyl)glycine. Focus on (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a novel and selective group II metabotropic glutamate receptors antagonist.
Pellicciari R, Marinozzi M, Natalini B, Costantino G, Luneia R, Giorgi G, Moroni F, Thomsen C. Pellicciari R, et al. Among authors: luneia r. J Med Chem. 1996 May 24;39(11):2259-69. doi: 10.1021/jm960059+. J Med Chem. 1996. PMID: 8667369