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1973 1
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79 results

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Page 1
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Among authors: lutz cm. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation.
López-Erauskin J, Bravo-Hernandez M, Presa M, Baughn MW, Melamed Z, Beccari MS, Agra de Almeida Quadros AR, Arnold-Garcia O, Zuberi A, Ling K, Platoshyn O, Niño-Jara E, Ndayambaje IS, McAlonis-Downes M, Cabrera L, Artates JW, Ryan J, Hermann A, Ravits J, Bennett CF, Jafar-Nejad P, Rigo F, Marsala M, Lutz CM, Cleveland DW, Lagier-Tourenne C. López-Erauskin J, et al. Among authors: lutz cm. Nat Neurosci. 2024 Jan;27(1):34-47. doi: 10.1038/s41593-023-01496-0. Epub 2023 Nov 23. Nat Neurosci. 2024. PMID: 37996528 Free PMC article.
Focused ultrasound-mediated brain genome editing.
Lao YH, Ji R, Zhou JK, Snow KJ, Kwon N, Saville E, He S, Chauhan S, Chi CW, Datta MS, Zhang H, Quek CH, Cai SS, Li M, Gaitan Y, Bechtel L, Wu SY, Lutz CM, Tomer R, Murray SA, Chavez A, Konofagou EE, Leong KW. Lao YH, et al. Among authors: lutz cm. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302910120. doi: 10.1073/pnas.2302910120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579143 Free PMC article.
A Comprehensive Atlas of AAV Tropism in the Mouse.
Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR. Walkey CJ, et al. Among authors: lutz cm. bioRxiv [Preprint]. 2024 Sep 10:2024.09.10.612279. doi: 10.1101/2024.09.10.612279. bioRxiv. 2024. Update in: Mol Ther. 2025 Mar 05;33(3):1282-1299. doi: 10.1016/j.ymthe.2025.01.041. PMID: 39314496 Free PMC article. Updated. Preprint.
A comprehensive atlas of AAV tropism in the mouse.
Walkey CJ, Snow KJ, Bulcha J, Cox AR, Martinez AE, Ljungberg MC, Lanza DG, De Giorgi M, Chuecos MA, Alves-Bezerra M, Suarez CF, Hartig SM, Hilsenbeck SG, Hsu CW, Saville E, Gaitan Y, Duryea J Jr, Hannigan S, Dickinson ME, Mirochnitchenko O, Wang D, Lutz CM, Heaney JD, Gao G, Murray SA, Lagor WR. Walkey CJ, et al. Among authors: lutz cm. Mol Ther. 2025 Mar 5;33(3):1282-1299. doi: 10.1016/j.ymthe.2025.01.041. Epub 2025 Jan 25. Mol Ther. 2025. PMID: 39863928
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice.
Sullivan JM, Bagnell AM, Alevy J, Avila EM, Mihaljević L, Saavedra-Rivera PC, Kong L, Huh JS, McCray BA, Aisenberg WH, Zuberi AR, Bogdanik L, Lutz CM, Qiu Z, Quinlan KA, Searson PC, Sumner CJ. Sullivan JM, et al. Among authors: lutz cm. Sci Transl Med. 2024 May 22;16(748):eadk1358. doi: 10.1126/scitranslmed.adk1358. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776392 Free PMC article.
Stathmin-2 enhances motor axon regeneration after injury independent of its binding to tubulin.
Beccari MS, Arnold-Garcia O, Baughn MW, Artates JW, McAlonis-Downes M, Lim J, Leyva-Cázares DF, Rubio-Lara HI, Ramirez-Rodriguez A, Bernal-Buenrostro CN, Murgia-Bay B, Rangel CK, Kim DH, Melamed Z, Lutz CM, Lagier-Tourenne C, Corbett KD, López-Erauskin J, Cleveland DW. Beccari MS, et al. Among authors: lutz cm. Proc Natl Acad Sci U S A. 2025 May 27;122(21):e2502294122. doi: 10.1073/pnas.2502294122. Epub 2025 May 20. Proc Natl Acad Sci U S A. 2025. PMID: 40392845
Amyotrophic lateral sclerosis and frontotemporal dementia mutation reduces endothelial TDP-43 and causes blood-brain barrier defects.
Cheemala A, Kimble AL, Burrage EN, Helming SB, Tyburski JD, Leclair NK, Omar OM, Zuberi AR, Murphy M, Jellison ER, Reese B, Hu X, Lutz CM, Yan R, Murphy PA. Cheemala A, et al. Among authors: lutz cm. Sci Adv. 2025 Apr 18;11(16):eads0505. doi: 10.1126/sciadv.ads0505. Epub 2025 Apr 16. Sci Adv. 2025. PMID: 40238886 Free PMC article.
79 results