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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1980 1
1981 1
1983 1
1985 1
1987 2
1988 2
1990 2
1993 2
1994 1
1995 1
1996 2
1999 1
2000 1
2001 1
2002 1
2005 2
2007 1
2008 1
2010 4
2011 1
2012 2
2013 4
2014 1
2015 1
2016 3
2017 4
2018 5
2019 4
2020 5
2021 3
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58 results
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Page 1
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens.
Gonçalves E, Segura-Cabrera A, Pacini C, Picco G, Behan FM, Jaaks P, Coker EA, van der Meer D, Barthorpe A, Lightfoot H, Mironenko T, Beck A, Richardson L, Yang W, Lleshi E, Hall J, Tolley C, Hall C, Mali I, Thomas F, Morris J, Leach AR, Lynch JT, Sidders B, Crafter C, Iorio F, Fawell S, Garnett MJ. Gonçalves E, et al. Among authors: lynch jt. Mol Syst Biol. 2020 Jul;16(7):e9405. doi: 10.15252/msb.20199405. Mol Syst Biol. 2020. PMID: 32627965 Free PMC article.
Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia.
Maiques-Diaz A, Spencer GJ, Lynch JT, Ciceri F, Williams EL, Amaral FMR, Wiseman DH, Harris WJ, Li Y, Sahoo S, Hitchin JR, Mould DP, Fairweather EE, Waszkowycz B, Jordan AM, Smith DL, Somervaille TCP. Maiques-Diaz A, et al. Among authors: lynch jt. Cell Rep. 2018 Mar 27;22(13):3641-3659. doi: 10.1016/j.celrep.2018.03.012. Cell Rep. 2018. PMID: 29590629 Free PMC article.
Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL.
Erdmann T, Klener P, Lynch JT, Grau M, Vočková P, Molinsky J, Tuskova D, Hudson K, Polanska UM, Grondine M, Mayo M, Dai B, Pfeifer M, Erdmann K, Schwammbach D, Zapukhlyak M, Staiger AM, Ott G, Berdel WE, Davies BR, Cruzalegui F, Trneny M, Lenz P, Barry ST, Lenz G. Erdmann T, et al. Among authors: lynch jt. Blood. 2017 Jul 20;130(3):310-322. doi: 10.1182/blood-2016-12-758599. Epub 2017 Feb 15. Blood. 2017. PMID: 28202458 Free article.
LSD1 inhibitors disrupt the GFI1 transcription repressor complex.
Maiques-Diaz A, Lynch JT, Spencer GJ, Somervaille TCP. Maiques-Diaz A, et al. Among authors: lynch jt. Mol Cell Oncol. 2018 Aug 1;5(4):e1481813. doi: 10.1080/23723556.2018.1481813. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30250927 Free PMC article.
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