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Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin.
Grasset EM, Dunworth M, Sharma G, Loth M, Tandurella J, Cimino-Mathews A, Gentz M, Bracht S, Haynes M, Fertig EJ, Ewald AJ. Grasset EM, et al. Sci Transl Med. 2022 Aug 3;14(656):eabn7571. doi: 10.1126/scitranslmed.abn7571. Epub 2022 Aug 3. Sci Transl Med. 2022. PMID: 35921474 Free PMC article.
We observed cancer cells progressing from epithelial to hybrid E/M and strongly mesenchymal patterns during invasion and from epithelial to a hybrid E/M pattern during colony formation. ...We observed a complex spectrum of epithelial, hybrid E/M, and mesenchy …
We observed cancer cells progressing from epithelial to hybrid E/M and strongly mesenchymal patterns during invasion and from epithel …
Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.
Vincenz C, Dixit VM. Vincenz C, et al. J Biol Chem. 1997 Mar 7;272(10):6578-83. doi: 10.1074/jbc.272.10.6578. J Biol Chem. 1997. PMID: 9045686 Free article.
M., Kischkel, K. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827). In this report, we describe the cloning and ch …
M., Kischkel, K. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M …
Long-term stable production of monocyte-colony inhibition factor (M-CIF) from CHO microcarrier perfusion cultures.
Kong D, Gentz R, Zhang J. Kong D, et al. Cytotechnology. 1998 Mar;26(2):131-8. doi: 10.1023/A:1007997412002. Cytotechnology. 1998. PMID: 22358551 Free PMC article.
Monocyte-colony inhibition factor (M-CIF) was produced in microcarrier perfusion cultures from engineered Chinese hamster ovary (CHO) cells. ...During the perfusion operation, cell density reached 2-6 10(6) cells/ml. Importantly, stable expression of M-CIF from the …
Monocyte-colony inhibition factor (M-CIF) was produced in microcarrier perfusion cultures from engineered Chinese hamster ovary (CHO) …
Multifrequency time-harmonic elastography for the measurement of liver viscoelasticity in large tissue windows.
Tzschätzsch H, Ipek-Ugay S, Trong MN, Guo J, Eggers J, Gentz E, Fischer T, Schultz M, Braun J, Sack I. Tzschätzsch H, et al. Ultrasound Med Biol. 2015 Mar;41(3):724-33. doi: 10.1016/j.ultrasmedbio.2014.11.009. Epub 2015 Jan 28. Ultrasound Med Biol. 2015. PMID: 25638319
Patients could be separated from controls by higher shear wave speeds (3.11 0.64 m/s, 2.14-4.81 m/s, vs. 1.74 0.10 m/s, 1.60-1.91 m/s) without significant degradation of data by high body mass index or ascites. Furthermore, the wave speed dispersion sl …
Patients could be separated from controls by higher shear wave speeds (3.11 0.64 m/s, 2.14-4.81 m/s, vs. 1.74 0.10 m/s, …
Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma.
Elbelt U, Trovato A, Kloth M, Gentz E, Finke R, Spranger J, Galas D, Weber S, Wolf C, König K, Arlt W, Büttner R, May P, Allolio B, Schneider JG. Elbelt U, et al. J Clin Endocrinol Metab. 2015 Jan;100(1):E119-28. doi: 10.1210/jc.2014-2648. J Clin Endocrinol Metab. 2015. PMID: 25279498 Free PMC article.
Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor.
Ni J, Fernandez MA, Danielsson L, Chillakuru RA, Zhang J, Grubb A, Su J, Gentz R, Abrahamson M. Ni J, et al. J Biol Chem. 1998 Sep 18;273(38):24797-804. doi: 10.1074/jbc.273.38.24797. J Biol Chem. 1998. PMID: 9733783 Free article.
The mature recombinant protein processed by insect cells had an N-terminal segment 7 residues longer than that of cystatin C and displayed reversible inhibition of papain and cathepsin L (Ki = 1.1 and 0.31 nM, respectively), but not cathepsin B. Like cystatin E/M, cystatin …
The mature recombinant protein processed by insect cells had an N-terminal segment 7 residues longer than that of cystatin C and displayed r …