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Gene Expression Signatures of BRCAness and Tumor Inflammation Define Subgroups of Early-Stage Hormone Receptor-Positive Breast Cancer Patients.

Schroth W, Büttner FA, Kandabarau S, Hoppe R, Fritz P, Kumbrink J, Kirchner T, Brauer HA, Ren Y, Henderson D, Madden SF, Sauer G, Fehm T, Wallwiener D, Fasching PA, Mürdter T, Schwab M, Brauch H; German Tamoxifen and AI Clinicians Group. Schroth W, et al. Among authors: murdter t. Clin Cancer Res. 2020 Dec 15;26(24):6523-6534. doi: 10.1158/1078-0432.CCR-20-1923. Epub 2020 Oct 2. Clin Cancer Res. 2020. PMID: 33008814

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Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same.

Brauch H, Schroth W, Mürdter T, Schwab M. Brauch H, et al. Among authors: murdter t. J Clin Oncol. 2019 Aug 1;37(22):1981-1982. doi: 10.1200/JCO.19.00507. Epub 2019 Jun 18. J Clin Oncol. 2019. PMID: 31211600 No abstract available.

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Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS.

Neef SK, Janssen N, Winter S, Wallisch SK, Hofmann U, Dahlke MH, Schwab M, Mürdter TE, Haag M. Neef SK, et al. Among authors: murdter te. Metabolites. 2020 Dec 1;10(12):494. doi: 10.3390/metabo10120494. Metabolites. 2020. PMID: 33271860 Free PMC article.

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Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids.

Stöhr D, Schmid JO, Beigl TB, Mack A, Maichl DS, Cao K, Budai B, Fullstone G, Kontermann RE, Mürdter TE, Tait SWG, Hagenlocher C, Pollak N, Scheurich P, Rehm M. Stöhr D, et al. Among authors: murdter te. Cell Death Differ. 2020 Nov;27(11):3037-3052. doi: 10.1038/s41418-020-0559-3. Epub 2020 May 20. Cell Death Differ. 2020. PMID: 32433558 Free PMC article.

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Pharmacogenomics of tamoxifen therapy.

Brauch H, Mürdter TE, Eichelbaum M, Schwab M. Brauch H, et al. Among authors: murdter te. Clin Chem. 2009 Oct;55(10):1770-82. doi: 10.1373/clinchem.2008.121756. Epub 2009 Jul 2. Clin Chem. 2009. PMID: 19574470 Review.

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Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS.

Neef SK, Winter S, Hofmann U, Mürdter TE, Schaeffeler E, Horn H, Buck A, Walch A, Hennenlotter J, Ott G, Fend F, Bedke J, Schwab M, Haag M. Neef SK, et al. Among authors: murdter te. Anal Chim Acta. 2020 Oct 16;1134:125-135. doi: 10.1016/j.aca.2020.08.005. Epub 2020 Aug 13. Anal Chim Acta. 2020. PMID: 33059858

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Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.

Mueller-Schoell A, Klopp-Schulze L, Schroth W, Mürdter T, Michelet R, Brauch H, Huisinga W, Joerger M, Neven P, Koolen SLW, Mathijssen RHJ, Copson E, Eccles D, Chen S, Chowbay B, Tfayli A, Zgheib NK, Schwab M, Kloft C. Mueller-Schoell A, et al. Among authors: murdter t. Clin Pharmacol Ther. 2020 Sep;108(3):661-670. doi: 10.1002/cpt.1960. Epub 2020 Jul 23. Clin Pharmacol Ther. 2020. PMID: 32578187

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Stereoselective quantification of phase 1 and 2 metabolites of clomiphene in human plasma and urine.

Kröner P, Heinkele G, Kerb R, Igel S, Schwab M, Mürdter TE. Kröner P, et al. Among authors: murdter te. Talanta. 2021 Jan 1;221:121658. doi: 10.1016/j.talanta.2020.121658. Epub 2020 Sep 16. Talanta. 2021. PMID: 33076169

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Subunits of BK channels promote breast cancer development and modulate responses to endocrine treatment in preclinical models.

Mohr CJ, Schroth W, Mürdter TE, Gross D, Maier S, Stegen B, Dragoi A, Steudel FA, Stehling S, Hoppe R, Madden S, Ruth P, Huber SM, Brauch H, Lukowski R. Mohr CJ, et al. Among authors: murdter te. Br J Pharmacol. 2020 May 28. doi: 10.1111/bph.15147. Online ahead of print. Br J Pharmacol. 2020. PMID: 32468618 Free article.

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The Influences of Adherence to Tamoxifen and CYP2D6 Pharmacogenetics on Plasma Concentrations of the Active Metabolite (Z)-Endoxifen in Breast Cancer.

Nardin JM, Schroth W, Almeida TA, Mürdter T, Picolotto S, Vendramini ECL, Hoppe R, Kogin JP, Miqueleto D, de Moraes SDR, Schwab M, Pecoits-Filho RF, Brauch H, Casali-da-Rocha JC. Nardin JM, et al. Among authors: murdter t. Clin Transl Sci. 2020 Mar;13(2):284-292. doi: 10.1111/cts.12707. Epub 2019 Nov 9. Clin Transl Sci. 2020. PMID: 31573754 Free PMC article.

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