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2019 2
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12 results

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Page 1
Cancer treatment monitoring using cell-free DNA fragmentomes.
van 't Erve I, Alipanahi B, Lumbard K, Skidmore ZL, Rinaldi L, Millberg LK, Carey J, Chesnick B, Cristiano S, Portwood C, Wu T, Peters E, Bolhuis K, Punt CJA, Tom J, Bach PB, Dracopoli NC, Meijer GA, Scharpf RB, Velculescu VE, Fijneman RJA, Leal A. van 't Erve I, et al. Nat Commun. 2024 Oct 21;15(1):8801. doi: 10.1038/s41467-024-53017-7. Nat Commun. 2024. PMID: 39433569 Free PMC article.
Deep generative AI models analyzing circulating orphan non-coding RNAs enable detection of early-stage lung cancer.
Karimzadeh M, Momen-Roknabadi A, Cavazos TB, Fang Y, Chen NC, Multhaup M, Yen J, Ku J, Wang J, Zhao X, Murzynowski P, Wang K, Hanna R, Huang A, Corti D, Nguyen D, Lam T, Kilinc S, Arensdorf P, Chau KH, Hartwig A, Fish L, Li H, Behsaz B, Elemento O, Zou J, Hormozdiari F, Alipanahi B, Goodarzi H. Karimzadeh M, et al. Nat Commun. 2024 Nov 21;15(1):10090. doi: 10.1038/s41467-024-53851-9. Nat Commun. 2024. PMID: 39572521 Free PMC article.
Combining cell-free DNA fragmentomes and total tumour volume improves prognostication and tumour response evaluation in patients with colorectal cancer liver metastases.
Crnovrsanin N, Zeeuw JM, Ali M, Kemna R, Alipanahi B, Lumbard K, Skidmore ZL, Rinaldi L, van 't Erve I, Wesdorp NJ, Huiskens J, van Steijn D, van Waesberghe JH, van den Bergh J, Nota I, Moos S, Bond MJG, Meiqari L, Huitink I, Giovannetti E, Stoker J, Verpalen I, van den Broek D, Meijer GA, Swijnenburg RJ, Punt CJA, Scharpf RB, Leal A, Dracopoli NC, Velculescu VE, Kok NFM, Kazemier G, Fijneman RJA. Crnovrsanin N, et al. EBioMedicine. 2026 Jan;123:106081. doi: 10.1016/j.ebiom.2025.106081. Epub 2025 Dec 16. EBioMedicine. 2026. PMID: 41406506 Free PMC article. Clinical Trial.
Detection of Early-Stage Colorectal Cancer Using Cell-Free oncRNA Biomarkers and Artificial Intelligence.
Momen-Roknabadi A, Karimzadeh M, Chen NC, Cavazos TB, Wang J, Ku J, Degtiar A, Krishnan A, Hernandez M, Gebala M, Huang A, Chen S, Nguyen D, Lam T, Hanna R, Fish L, Smith AJ, Sekhon S, Yen J, Gregg J, Li H, Hormozdiari F, Behsaz B, Hartwig A, Goodarzi H, Schwartzberg L, Alipanahi B. Momen-Roknabadi A, et al. Clin Cancer Res. 2025 Aug 1;31(15):3229-3238. doi: 10.1158/1078-0432.CCR-25-0449. Clin Cancer Res. 2025. PMID: 40366744 Free PMC article.
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
Gallagher CS, Mäkinen N, Harris HR, Rahmioglu N, Uimari O, Cook JP, Shigesi N, Ferreira T, Velez-Edwards DR, Edwards TL, Mortlock S, Ruhioglu Z, Day F, Becker CM, Karhunen V, Martikainen H, Järvelin MR, Cantor RM, Ridker PM, Terry KL, Buring JE, Gordon SD, Medland SE, Montgomery GW, Nyholt DR, Hinds DA, Tung JY; 23andMe Research Team; Perry JRB, Lind PA, Painter JN, Martin NG, Morris AP, Chasman DI, Missmer SA, Zondervan KT, Morton CC. Gallagher CS, et al. Nat Commun. 2019 Oct 24;10(1):4857. doi: 10.1038/s41467-019-12536-4. Nat Commun. 2019. PMID: 31649266 Free PMC article.
The effect of LRRK2 loss-of-function variants in humans.
Whiffin N, Armean IM, Kleinman A, Marshall JL, Minikel EV, Goodrich JK, Quaife NM, Cole JB, Wang Q, Karczewski KJ, Cummings BB, Francioli L, Laricchia K, Guan A, Alipanahi B, Morrison P, Baptista MAS, Merchant KM; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium; Ware JS, Havulinna AS, Iliadou B, Lee JJ, Nadkarni GN, Whiteman C; 23andMe Research Team; Daly M, Esko T, Hultman C, Loos RJF, Milani L, Palotie A, Pato C, Pato M, Saleheen D, Sullivan PF, Alföldi J, Cannon P, MacArthur DG. Whiffin N, et al. Nat Med. 2020 Jun;26(6):869-877. doi: 10.1038/s41591-020-0893-5. Epub 2020 May 27. Nat Med. 2020. PMID: 32461697 Free PMC article.
Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease.
Lai D, Alipanahi B, Fontanillas P, Schwantes-An TH, Aasly J, Alcalay RN, Beecham GW, Berg D, Bressman S, Brice A, Brockman K, Clark L, Cookson M, Das S, Van Deerlin V, Follett J, Farrer MJ, Trinh J, Gasser T, Goldwurm S, Gustavsson E, Klein C, Lang AE, Langston JW, Latourelle J, Lynch T, Marder K, Marras C, Martin ER, McLean CY, Mejia-Santana H, Molho E, Myers RH, Nuytemans K, Ozelius L, Payami H, Raymond D, Rogaeva E, Rogers MP, Ross OA, Samii A, Saunders-Pullman R, Schüle B, Schulte C, Scott WK, Tanner C, Tolosa E, Tomkins JE, Vilas D, Trojanowski JQ; 23andMe Research Team; Uitti R, Vance JM, Visanji NP, Wszolek ZK, Zabetian CP, Mirelman A, Giladi N, Orr Urtreger A, Cannon P, Fiske B, Foroud T. Lai D, et al. Ann Neurol. 2021 Jul;90(1):76-88. doi: 10.1002/ana.26094. Epub 2021 May 17. Ann Neurol. 2021. PMID: 33938021 Free PMC article.
Author Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG.
Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA, Nguyen-Viet TA, Wedow R, Zacher M, Furlotte NA; 23andMe Research Team; Social Science Genetic Association Consortium; Magnusson P, Oskarsson S, Johannesson M, Visscher PM, Laibson D, Cesarini D, Neale BM, Benjamin DJ. Turley P, et al. Nat Genet. 2019 Aug;51(8):1295. doi: 10.1038/s41588-019-0469-9. Nat Genet. 2019. PMID: 31239548
The 'Competing interests' statement should have stated that B.M.N. is on the Scientific Advisory Board of Deep Genomics. The error has been corrected in the HTML and PDF versions of the article....
The 'Competing interests' statement should have stated that B.M.N. is on the Scientific Advisory Board of Deep Genomics. The error ha …
12 results