Inhibition of mitochondria induces apoptosis and reduces telomere length and activity in acute myeloid leukemia stem cells.
Valipour B, Davari S, Farahzadi R, Pourrasol S, Mehran N, Dizaji Asl K, Altaha SM, Hojjati Z, Nozad Charoudeh H.
Valipour B, et al.
Cell Biochem Funct. 2023 Dec;41(8):1477-1487. doi: 10.1002/cbf.3888. Epub 2023 Nov 28.
Cell Biochem Funct. 2023.
PMID: 38014526
In the following, these cells were treated with 20 M (IC50) tigecycline. The expression of Annexin/PI, Caspase 3, apoptotic genes (BCL2, BCLX, BAX, BAD, and P53) and proteins (P53, BAX, BCL2 and Caspase 9) was evaluated in CD34(+) , CD34(-) and KG-1a AML cells. ...
In the following, these cells were treated with 20 M (IC50) tigecycline. The expression of Annexin/PI, Caspase 3, apoptotic genes (BC …