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Biomolecular interactions and binding dynamics of inhibitor arachidonic acid, with tyrosinase enzyme.
Shojazadeh T, Zolghadr L, JafarKhani S, Gharaghani S, Farasat A, Piri H, Gheibi N. Shojazadeh T, et al. J Biomol Struct Dyn. 2023 Mar;41(4):1378-1387. doi: 10.1080/07391102.2021.2020167. Epub 2022 Jan 3. J Biomol Struct Dyn. 2023. PMID: 34974821
Based on the kinetic results, arachidonic acid showed mixed-type of inhibition with Ki = 4.7 M. Fluorescence and CD studies showed changes of secondary and tertiary structures of enzyme and a reduction of alpha-helix* amino acids after its incubation with different concen …
Based on the kinetic results, arachidonic acid showed mixed-type of inhibition with Ki = 4.7 M. Fluorescence and CD studies showed c …
New insights into the inhibitory effect of phenol carboxylic acid antioxidants on mushroom tyrosinase by molecular dynamic studies and experimental assessment.
Shojazadeh T, Zolghadr L, Gharaghani S, JafarKhani S, Molaabasi F, Piri H, Gheibi N. Shojazadeh T, et al. J Biomol Struct Dyn. 2023;41(22):13404-13414. doi: 10.1080/07391102.2023.2175038. Epub 2023 Mar 1. J Biomol Struct Dyn. 2023. PMID: 36856125
The inhibitor effects against monophenolase activity were in a reversible and competitive manner with ki value equal to 6.8 and 7.5 M respectively. The affinity between tyrosinase and L-DOPA decreased when fatty acids were added to the solution. ...
The inhibitor effects against monophenolase activity were in a reversible and competitive manner with ki value equal to 6.8 and 7.5 M …
Continuous exposure to ambient air pollution and chronic diseases: prevalence, burden, and economic costs.
Karimi SM, Maziyaki A, Ahmadian Moghadam S, Jafarkhani M, Zarei H, Moradi-Lakeh M, Pouran H. Karimi SM, et al. Rev Environ Health. 2020 Apr 22;35(4):379-399. doi: 10.1515/reveh-2019-0106. Print 2020 Nov 18. Rev Environ Health. 2020. PMID: 32324166
The single-pollutant analysis showed that a one-unit increase in monthly CO (ppm), NO(2) (ppb), O(3) (ppb), and PM10 (mug/m(3)) during the 2 years was associated with 751 [confidence interval (CI): 512-990], 18 (CI: 12-24), 46 (CI: -27-120), and 24 (CI: 13-35) more reporte …
The single-pollutant analysis showed that a one-unit increase in monthly CO (ppm), NO(2) (ppb), O(3) (ppb), and PM10 (mug/m(3)) durin …