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Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells.
Lerner RG, Grossauer S, Kadkhodaei B, Meyers I, Sidorov M, Koeck K, Hashizume R, Ozawa T, Phillips JJ, Berger MS, Nicolaides T, James CD, Petritsch CK. Lerner RG, et al. Cancer Res. 2015 Dec 15;75(24):5355-66. doi: 10.1158/0008-5472.CAN-14-3689. Epub 2015 Nov 16. Cancer Res. 2015. PMID: 26573800 Free PMC article.
We show that CD133(+) cells exhibited decreased sensitivity to the antiproliferative effects of BRAF/MAPK inhibition compared to CD133(-) cells. Furthermore, CD133(+) cells exhibited an extended G2-M phase and increased polarized asymmetric cell divisions. At the molecular …
We show that CD133(+) cells exhibited decreased sensitivity to the antiproliferative effects of BRAF/MAPK inhibition compared to CD133(-) ce …
"Bowel wall hemorrhage": a characteristic sign in hanging death.
Okazi A, Taghaddosinejad F, Mobaraki H, Kadkhodaei AR, Yousefinejad V. Okazi A, et al. J Forensic Leg Med. 2014 Jan;21:42-5. doi: 10.1016/j.jflm.2013.10.018. Epub 2013 Nov 5. J Forensic Leg Med. 2014. PMID: 24365687
The mean of height, weight and BMI were 173.25 6.06 cm, 71.56 7.76 kg, and 28.80 2.01 kg/m(2) respectively. Hanging was complete in 9 cases (56.2%). Our findings show that after exclusion of other conditions leading to intra-abdominal congestion, presence of bowel wall hem …
The mean of height, weight and BMI were 173.25 6.06 cm, 71.56 7.76 kg, and 28.80 2.01 kg/m(2) respectively. Hanging was complete in 9 …