Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis.
Rockhold JD, Marszalkowski H, Sannella M, Gibney K, Murphy L, Zukowski E, Kalantar GH, SantaCruz-Calvo S, Hart SN, Kuhn MK, Yu J, Stefanik O, Chase G, Proctor EA, Hasturk H, Nikolajczyk BS, Bharath LP.
Rockhold JD, et al.
Geroscience. 2024 Dec;46(6):5681-5699. doi: 10.1007/s11357-024-01187-z. Epub 2024 May 18.
Geroscience. 2024.
PMID: 38761287
Free PMC article.
CD4(+) T cells from older adults were treated with a physiological dose of everolimus (0.01 M), and indices of autophagy and inflammation were assessed to gain a mechanistic understanding of the effect of everolimus on inflammation. ...
CD4(+) T cells from older adults were treated with a physiological dose of everolimus (0.01 M), and indices of autophagy and inflamma …