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Page 1
Efficacy of iGlarLixi on 5-year risk of diabetes-related complications: A simulation study.
Shao H, Kianmehr H, Guo J, Li P, Fonseca V, Shi L. Shao H, et al. J Diabetes Complications. 2022 Mar;36(3):108132. doi: 10.1016/j.jdiacomp.2022.108132. Epub 2022 Jan 25. J Diabetes Complications. 2022. PMID: 35101326
RESULTS: iGlarLixi compared with SOC was found to reduce HbA1c (-1.4%), SBP (-3.4 mm Hg), and BMI (-0.6 kg/m(2)) in six months. We simulated a 5-year risk reduction in major adverse cardiovascular events (MACE) (relative risk [RR] 0.77, 95% CI: 0.67-0.88), and all-cause mo …
RESULTS: iGlarLixi compared with SOC was found to reduce HbA1c (-1.4%), SBP (-3.4 mm Hg), and BMI (-0.6 kg/m(2)) in six months. We si …
Renal function as an effect modifier of intensive glucose control in delaying cognitive function decline among individuals with type 2 diabetes: A revisit to the ACCORD MIND trial.
Li P, Kianmehr H, Guan D, Kulshreshtha A, Narayan KMV, Ali MK, Umpierrez GE, Hu X, Fonseca VA, Shi L, Shao H. Li P, et al. Diabetes Obes Metab. 2024 Sep;26(9):3958-3968. doi: 10.1111/dom.15744. Epub 2024 Jul 4. Diabetes Obes Metab. 2024. PMID: 38962812 Free PMC article. Clinical Trial.
Patients with preserved renal function (estimated glomerular filtration rate between 60 and 90 ml/min/1.73 m(2)) were associated with small benefits (AFC: 1.28 in Stroop, 95% CI: 0.28, 2.27, Cohen's d: 0.12) when undergoing intensive glucose control. Conversely, participan …
Patients with preserved renal function (estimated glomerular filtration rate between 60 and 90 ml/min/1.73 m(2)) were associated with …
Enzymatic characterization of a NADH-dependent diaphorase from Lysinibacillus sp. strain PAD-91.
Kianmehr A, Oladnabi M, Mahrooz A, Ansari J, Mahdizadeh R. Kianmehr A, et al. Protein Expr Purif. 2018 Jun;146:1-7. doi: 10.1016/j.pep.2018.01.005. Protein Expr Purif. 2018. PMID: 29414067
The optimum pH and temperature for the catalytic activity of the enzyme was about pH 7.5 and 30 C. The K(m) and V(max) values were estimated to be 0.025 mM and 1.33 mumol/min, respectively. ...
The optimum pH and temperature for the catalytic activity of the enzyme was about pH 7.5 and 30 C. The K(m) and V(max) values were e …
Some patients with type 2 diabetes may benefit from intensive glycaemic and blood pressure control: A post-hoc machine learning analysis of ACCORD trial data.
Jiao T, Kianmehr H, Lin Y, Li P, Singh Ospina N, Ghayee HK, Ruzieh M, Fonseca V, Shi L, Zhang P, Shao H. Jiao T, et al. Diabetes Obes Metab. 2024 Apr;26(4):1502-1509. doi: 10.1111/dom.15453. Epub 2024 Jan 31. Diabetes Obes Metab. 2024. PMID: 38297986 Free PMC article.
RESULTS: Compared with standard glucose control, intensive one reduced MACE in those with baseline HbA1c <8.5% [relative risk (RR): 0.79, 95% confidence interval (CI): 0.67-0.93] and those with estimated glomerular filtration rate 106 ml/min/1.73 m(2) (RR: 0.74, 95% CI …
RESULTS: Compared with standard glucose control, intensive one reduced MACE in those with baseline HbA1c <8.5% [relative risk (RR): 0.79, …
DNA damage assessment in the lymphocytes of construction painters by comet assay.
Kianmehr M, Amiri M, Ebrahimzadeh-Bideskan A, Hajavi J. Kianmehr M, et al. Toxicol Ind Health. 2016 Nov;32(11):1902-1909. doi: 10.1177/0748233715597347. Epub 2016 Jul 10. Toxicol Ind Health. 2016. PMID: 26319236
The DNA damage in the painter group was significantly greater than that of the control group. Tail length ( m) was 12.63 6.54 versus 2.90 0.84, tail DNA (%) was 4.33 1.84 versus 1.29 0.43, and tail moment ( m) was 1.85 0.98 versus 0.14 0.20 in painter an …
The DNA damage in the painter group was significantly greater than that of the control group. Tail length ( m) was 12.63 6.54 versu …
Improving sustainability and mitigating environmental impacts of agro-biowaste compost fertilizer by pelletizing-drying.
Sarlaki E, Kermani AM, Kianmehr MH, Asefpour Vakilian K, Hosseinzadeh-Bandbafha H, Ma NL, Aghbashlo M, Tabatabaei M, Lam SS. Sarlaki E, et al. Environ Pollut. 2021 Sep 15;285:117412. doi: 10.1016/j.envpol.2021.117412. Epub 2021 May 20. Environ Pollut. 2021. PMID: 34051566
The density, specific crushing energy, and moisture diffusion of agro-biowaste compost pellet at the optimal conditions were 1242.49 kg/m(3), 0.5054 MJ/t, and 8.2 10(-8) m(2)/s, respectively. The optimal biocompost pellet could release 80% of its nitrogen content …
The density, specific crushing energy, and moisture diffusion of agro-biowaste compost pellet at the optimal conditions were 1242.49 kg/m …
Recombinant expression, characterization and application of a dihydrolipoamide dehydrogenase with diaphorase activity from Bacillus sphaericus.
Kianmehr A, Mahdizadeh R, Oladnabi M, Ansari J. Kianmehr A, et al. 3 Biotech. 2017 Jun;7(2):153. doi: 10.1007/s13205-017-0763-0. Epub 2017 Jun 8. 3 Biotech. 2017. PMID: 28597164 Free PMC article.
Different metal ions and inhibitors showed no influence on the activity of target enzyme. The K (m) and V (max) values for NADH were estimated to be 0.33 mM and 200.0 U/ml, respectively. ...
Different metal ions and inhibitors showed no influence on the activity of target enzyme. The K (m) and V (max) values for NADH were …
Immobilization of lipase on the modified magnetic diatomite earth for effective methyl esterification of isoamyl alcohol to synthesize banana flavor.
Vakili F, Mojtabavi S, Imanparast S, Kianmehr Z, Forootanfar H, Faramarzi MA. Vakili F, et al. 3 Biotech. 2020 Oct;10(10):447. doi: 10.1007/s13205-020-02437-5. Epub 2020 Sep 23. 3 Biotech. 2020. PMID: 33062576 Free PMC article.
PPL@mDE demonstrated higher storage stability than the free enzyme at 4 C, 25 C, and 37 C. The apparent K (m) (2.35 0.12 mM) and V (max) (13.01 0.64 mol/min) values for the immobilized enzyme were considerably altered compared to those of the free enzyme (p > 0. …
PPL@mDE demonstrated higher storage stability than the free enzyme at 4 C, 25 C, and 37 C. The apparent K (m) (2.35 0.12 mM) and …
Assessment of DNA damage in blood lymphocytes of bakery workers by comet assay.
Kianmehr M, Hajavi J, Gazeri J. Kianmehr M, et al. Toxicol Ind Health. 2017 Sep;33(9):726-735. doi: 10.1177/0748233717712408. Epub 2017 Sep 1. Toxicol Ind Health. 2017. PMID: 28862089
There was greater peripheral blood lymphocyte DNA damage in bakers who had been using firewood for fuel compared to those using other types of fuel to such an extent that tail moments ( m) for firewood-burning bakers was 4.40 1.98 versus 1.35 0.84 for natural gas, 1.85 …
There was greater peripheral blood lymphocyte DNA damage in bakers who had been using firewood for fuel compared to those using other types …
Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes.
Mahrooz A, Hashemi-Soteh MB, Heydari M, Boorank R, Ramazani F, Mahmoudi A, Kianmehr A, Alizadeh A. Mahrooz A, et al. Clin Chim Acta. 2018 Sep;484:40-46. doi: 10.1016/j.cca.2018.05.037. Epub 2018 May 19. Clin Chim Acta. 2018. PMID: 29782842
Based on gamma correlation, there was a significant inverse association between the number of M alleles of the PON1-L55M and HbA1c levels (r = -0.261, p = 0.001). CONCLUSIONS: Sex should be considered a confounding variable in association studies on the variants PON1-Q192R …
Based on gamma correlation, there was a significant inverse association between the number of M alleles of the PON1-L55M and HbA1c le …
11 results