In vivo pharmacokinetics, biodistribution and anti-tumor effect of paclitaxel-loaded targeted chitosan-based polymeric micelle.
Rezazadeh M, Emami J, Hasanzadeh F, Sadeghi H, Minaiyan M, Mostafavi A, Rostami M, Lavasanifar A.
Rezazadeh M, et al.
Drug Deliv. 2016 Jun;23(5):1707-17. doi: 10.3109/10717544.2014.954281. Epub 2014 Sep 4.
Drug Deliv. 2016.
PMID: 25188785
Free article.
The IC50 value of PTX, a concentration at which 50% cells are killed, was 1.17 and 0.93 M for Anzatax and PTX/TS-CS-PEG-FA micelles, respectively. The in vivo anti-tumor efficacy of PTX/TS-CS-PEG-FA, as measured by reduction in tumor volume of 4T1 mouse breast cancer inj …
The IC50 value of PTX, a concentration at which 50% cells are killed, was 1.17 and 0.93 M for Anzatax and PTX/TS-CS-PEG-FA micelles …