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2009 2
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Page 1
Modelling of mass transport and distribution of aptamer in blood-brain barrier for tumour therapy and cancer treatment.
Sarafraz M, Nakhjavani M, Shigdar S, Christo FC, Rolfe B. Sarafraz M, et al. Eur J Pharm Biopharm. 2022 Apr;173:121-131. doi: 10.1016/j.ejpb.2022.03.004. Epub 2022 Mar 10. Eur J Pharm Biopharm. 2022. PMID: 35283304
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was developed accounting for the fluid flow and mass transport of the aptamer molecule inside an 8 m capillary vessel across a 14 m bl …
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was develo …
The Preventive Effect of L-Lysine on Lysozyme Glycation in Type 2 Diabetes.
Mirmiranpour H, Khaghani S, Bathaie SZ, Nakhjavani M, Kebriaeezadeh A, Ebadi M, Gerayesh-Nejad S, Zangooei M. Mirmiranpour H, et al. Acta Med Iran. 2016 Jan;54(1):24-31. Acta Med Iran. 2016. PMID: 26853287 Free article. Clinical Trial.
Lysozyme was incubated with glucose and/or L-lysine, followed by an investigation of its structure by electrophoresis, fluorescence spectroscopy, and circular dichroism spectroscopy and also assessment of its bactericidal activity against M. lysodeikticus. In the clinical …
Lysozyme was incubated with glucose and/or L-lysine, followed by an investigation of its structure by electrophoresis, fluorescence spectros …
Anti-Cancer Effects of an Optimised Combination of Ginsenoside Rg3 Epimers on Triple Negative Breast Cancer Models.
Nakhjavani M, Smith E, Palethorpe HM, Tomita Y, Yeo K, Price TJ, Townsend AR, Hardingham JE. Nakhjavani M, et al. Pharmaceuticals (Basel). 2021 Jun 30;14(7):633. doi: 10.3390/ph14070633. Pharmaceuticals (Basel). 2021. PMID: 34208799 Free PMC article.
Here, we show that the optimised combination of 50 M SRg3 and 25 M RRg3 (C3), derived from an RSM model of migration of TNBC cell line MDA-MB-231, inhibited migration of MDA-MB-231 and HCC1143, in 2D and 3D migration assays (p < 0.0001). ...
Here, we show that the optimised combination of 50 M SRg3 and 25 M RRg3 (C3), derived from an RSM model of migration of TNBC …
Distribution of Helicobacter pylori cagA, cagE, oipA and vacA in different major ethnic groups in Tehran, Iran.
Dabiri H, Maleknejad P, Yamaoka Y, Feizabadi MM, Jafari F, Rezadehbashi M, Nakhjavani FA, Mirsalehian A, Zali MR. Dabiri H, et al. J Gastroenterol Hepatol. 2009 Aug;24(8):1380-6. doi: 10.1111/j.1440-1746.2009.05876.x. J Gastroenterol Hepatol. 2009. PMID: 19702906 Free PMC article.
The presence of the cagA, cagE and oipA genes and vacA alleles (signal [s] and middle [m] region) were determined by polymerase chain reaction (PCR) from H. pylori DNA. RESULTS: The cagA-positive status was predominant in all three ethnic groups (e.g. 65% in Persians and 7 …
The presence of the cagA, cagE and oipA genes and vacA alleles (signal [s] and middle [m] region) were determined by polymerase chain …
Appropriate BMI cut-off values for identification of metabolic risk factors: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007).
Zandieh A, Esteghamati A, Morteza A, Noshad S, Khalilzadeh O, Gouya MM, Nakhjavani M. Zandieh A, et al. Ann Hum Biol. 2012 Nov-Dec;39(6):484-9. doi: 10.3109/03014460.2012.716860. Epub 2012 Sep 5. Ann Hum Biol. 2012. PMID: 22946480 Free article.
The appropriate BMI cut-offs ranged from 24.6-26.1 kg/m(2) for men and from 26.9-28.8 kg/m(2) for women. The optimal BMI cut-offs for identifying any two or more of those risk factors were 25.2 and 27.3 kg/m(2) in men and women, respectively. CONCLUSION: In m …
The appropriate BMI cut-offs ranged from 24.6-26.1 kg/m(2) for men and from 26.9-28.8 kg/m(2) for women. The optimal BMI cut-o …
Trends in the prevalence of diabetes and impaired fasting glucose in association with obesity in Iran: 2005-2011.
Esteghamati A, Etemad K, Koohpayehzadeh J, Abbasi M, Meysamie A, Noshad S, Asgari F, Mousavizadeh M, Rafei A, Khajeh E, Neishaboury M, Sheikhbahaei S, Nakhjavani M. Esteghamati A, et al. Diabetes Res Clin Pract. 2014 Feb;103(2):319-27. doi: 10.1016/j.diabres.2013.12.034. Epub 2014 Jan 3. Diabetes Res Clin Pract. 2014. PMID: 24447808
PAF analysis demonstrated that 33.78%, 10.25%, and 30.56% of the prevalent DM can be attributed to overweight (BMI 25kg/m(2)), general obesity (BMI 30 kg/m(2)), and central obesity (waist circumference 90 cm), respectively. ...
PAF analysis demonstrated that 33.78%, 10.25%, and 30.56% of the prevalent DM can be attributed to overweight (BMI 25kg/m(2)), genera …
Bacopasides I and II Act in Synergy to Inhibit the Growth, Migration and Invasion of Breast Cancer Cell Lines.
Palethorpe HM, Smith E, Tomita Y, Nakhjavani M, Yool AJ, Price TJ, Young JP, Townsend AR, Hardingham JE. Palethorpe HM, et al. Molecules. 2019 Sep 30;24(19):3539. doi: 10.3390/molecules24193539. Molecules. 2019. PMID: 31574930 Free PMC article.
Cell loss occurred at the highest dose combinations and was associated with G2/M arrest and apoptosis. Migration in the scratch wound assay was significantly reduced at apoptosis-inducing combinations, but also at non-cytotoxic combinations, for MDA-MB-231 and T47D (p < …
Cell loss occurred at the highest dose combinations and was associated with G2/M arrest and apoptosis. Migration in the scratch wound …
Low Ankle-Brachial Index Is Associated With Albuminuria and Diabetic Kidney Disease in Type 2 Diabetes; A Cross Sectional Study.
Moshkele MH, Mirmoosavi S, Najafi MT, Karimpour S, Esteghamati A, Nakhjavani M, Rabizadeh S. Moshkele MH, et al. Endocrinol Diabetes Metab. 2025 Nov;8(6):e70115. doi: 10.1002/edm2.70115. Endocrinol Diabetes Metab. 2025. PMID: 41204636 Free PMC article.
DKD was defined as albuminuria [urinary albumin > 30 mg/g cr] and/or eGFR < 60 mL/min/1.73 m(2). Binary logistic regression assessed the association between ABI and both albuminuria and DKD, adjusting for confounders. ...

DKD was defined as albuminuria [urinary albumin > 30 mg/g cr] and/or eGFR < 60 mL/min/1.73 m(2). Binary logistic regression ass

…
Short term effects of spironolactone on blood lipid profile: a 3-month study on a cohort of young women with hirsutism.
Nakhjavani M, Hamidi S, Esteghamati A, Abbasi M, Nosratian-Jahromi S, Pasalar P. Nakhjavani M, et al. Br J Clin Pharmacol. 2009 Oct;68(4):634-7. doi: 10.1111/j.1365-2125.2009.03483.x. Br J Clin Pharmacol. 2009. PMID: 19843067 Free PMC article.
RESULTS: Mean body mass index of patients was 26.1 +/- 5.1 kg m(-2) before treatment and 25.9 +/- 5.7 kg m(-2) after treatment (NS). The therapy was associated with a significant decline of mean high-density lipoprotein (HDL), 39.5 mg dl(-1)[95% confidence interval …
RESULTS: Mean body mass index of patients was 26.1 +/- 5.1 kg m(-2) before treatment and 25.9 +/- 5.7 kg m(-2) after treatment …
Intracellular GSH Alterations and Its Relationship to Level of Resistance following Exposure to Cisplatin in Cancer Cells.
Jamali B, Nakhjavani M, Hosseinzadeh L, Amidi S, Nikounezhad N, H Shirazi F. Jamali B, et al. Iran J Pharm Res. 2015 Spring;14(2):513-9. Iran J Pharm Res. 2015. PMID: 25901159 Free PMC article.
MTT assay was performed to measure cytotoxicity of cisplatin (33.3 M for 1 hour). Following cisplatin exposure, GSHi (per million cells) was evaluated using a photometrical assay up to 90 minutes. ...
MTT assay was performed to measure cytotoxicity of cisplatin (33.3 M for 1 hour). Following cisplatin exposure, GSHi (per million ce …
12 results