Correlates of 5-year decline in 6-min walk distance in the COPDGene cohort.
Boriek AM, Gordon J, Gwon Y, Adami A, Porszasz J, Rossiter HB, Rambod M, Chandra D, Diaz AA, Kinney GL, Make BJ, McDonald MN, Regan EA, Rennard S, van Beek EJR, Casaburi R.
Boriek AM, et al.
Thorax. 2026 Jun 15;81(7):664-671. doi: 10.1136/thorax-2025-224183.
Thorax. 2026.
PMID: 41980814
COPD participants experienced greater 6MWD decline (44.1 101.9 m, p<0.001) compared with those with normal spirometry (28.5 101.0 m, p<0.001). Only baseline 6MWD and study site accounted for appreciable fractions of 6MWD decline variance (R(2)=12.1% and 9.1%, …
COPD participants experienced greater 6MWD decline (44.1 101.9 m, p<0.001) compared with those with normal spirometry (28.5 101.0 …