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13 results

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Page 1
1-Phenyl-β-carboline-3-carboxamide-1,2,3-triazole-N-phenylacetamide hybrids as new α-glucosidase inhibitors.
Safaie E, Sayahi MH, Dastyafteh N, Halimi M, Noori M, Mohammadi-Khanaposhtani M, Zonouzi A, Mirzazadeh R, Tajmir-Riahi A, Mojtabavi S, Faramarzi MA, Larijani B, Asadi M, Mahdavi M. Safaie E, et al. Sci Rep. 2025 May 20;15(1):17418. doi: 10.1038/s41598-025-99807-x. Sci Rep. 2025. PMID: 40394178 Free PMC article.
In vitro anti-alpha-glucosidase assay demonstrated that all the new fourteen derivatives with IC(50) values ranging from 64.0 to 661.4 M were more potent than positive control acarbose with IC(50) value of 750.0 and in vitro kinetic study revealed that the most potent com …
In vitro anti-alpha-glucosidase assay demonstrated that all the new fourteen derivatives with IC(50) values ranging from 64.0 to 661.4 M …
40-years of Lake Urmia restoration research: Review, synthesis and next steps.
Parsinejad M, Rosenberg DE, Ghale YAG, Khazaei B, Null SE, Raja O, Safaie A, Sima S, Sorooshian A, Wurtsbaugh WA. Parsinejad M, et al. Sci Total Environ. 2022 Aug 1;832:155055. doi: 10.1016/j.scitotenv.2022.155055. Epub 2022 Apr 6. Sci Total Environ. 2022. PMID: 35395306 Review.
We find: (1) Expansion of irrigated agriculture, dam construction, and mismanagement impacted the lake more than temperature increases and precipitation decreases. (2) Aerosols from Lake Urmia's exposed lakebed are negatively impacting human health. (3) Researchers disagree on ho …
We find: (1) Expansion of irrigated agriculture, dam construction, and mismanagement impacted the lake more than temperature increases and p …
Design of new α-glucosidase inhibitors based on the bis-4-hydroxycoumarin skeleton: Synthesis, evaluation, and in silico studies.
Soleimani Z, Mohammadi M, Halimi M, Safapoor S, Dastyafteh N, Safaie E, Mojtabavi S, Faramarzi MA, Bozorgi-Koushalshahi M, Larijani B, Mohammadi-Khanaposhtani M, Mahdavi M. Soleimani Z, et al. Sci Rep. 2024 Aug 12;14(1):18693. doi: 10.1038/s41598-024-69592-0. Sci Rep. 2024. PMID: 39134641 Free PMC article.
In this work, we have reported the design, synthesis, in vitro, and in silico enzymatic evaluation of new bis-4-hydroxycoumarin-based phenoxy-1,2,3-triazole-N-phenylacetamide derivatives 5a-m as potent alpha-glucosidase inhibitors. All the synthesized analogues showed high …
In this work, we have reported the design, synthesis, in vitro, and in silico enzymatic evaluation of new bis-4-hydroxycoumarin-based phenox …
Inducing Tolerance to Abiotic Stress in Hordeum vulgare L. by Halotolerant Endophytic Fungi Associated With Salt Lake Plants.
Hosseyni Moghaddam MS, Safaie N, Rahimlou S, Hagh-Doust N. Hosseyni Moghaddam MS, et al. Front Microbiol. 2022 May 20;13:906365. doi: 10.3389/fmicb.2022.906365. eCollection 2022. Front Microbiol. 2022. PMID: 35722330 Free PMC article.
To perform this experiment, a randomized block design was applied with three factors: fungi (four levels including three halotolerant endophytic species and control), salinity (three levels including 8, 12, and 16 dS/m), and drought (four levels including 100, 80, 60, 40 p …
To perform this experiment, a randomized block design was applied with three factors: fungi (four levels including three halotolerant endoph …
Association of Small Fiber Function with Microvascular Perfusion of Peripheral Nerves in Patients with Type 2 Diabetes : Study using Quantitative Sensory Testing and Magnetic Resonance Neurography.
Mooshage CM, Schimpfle L, Kender Z, Tsilingiris D, Aziz-Safaie T, Hohmann A, Szendroedi J, Nawroth P, Sturm V, Heiland S, Bendszus M, Kopf S, Kurz FT, Jende JME. Mooshage CM, et al. Clin Neuroradiol. 2024 Mar;34(1):55-66. doi: 10.1007/s00062-023-01328-5. Epub 2023 Aug 7. Clin Neuroradiol. 2024. PMID: 37548682 Free PMC article.
The Role of Cell Wall Degrading Enzymes in Antagonistic Traits of Trichoderma virens Against Rhizoctonia solani.
Ghasemi S, Safaie N, Shahbazi S, Shams-Bakhsh M, Askari H. Ghasemi S, et al. Iran J Biotechnol. 2020 Oct 1;18(4):e2333. doi: 10.30498/IJB.2020.2333. eCollection 2020 Oct. Iran J Biotechnol. 2020. PMID: 34056015 Free PMC article.
The highest extracellular protein production in the supernatant of chitinase and cellulase TFM was observed for the T.vi M(11) and T.vi M(17) strains, respectively. The T.vi M(12) and wild-type strains secreted chitinase and cellulase significantly more than …
The highest extracellular protein production in the supernatant of chitinase and cellulase TFM was observed for the T.vi M(11) and T. …
Mode of action of 3-butylidene phthalide as a competent natural pesticide.
Abbod M, Safaie N, Gholivand K, Mehrabadi M, Bonsaii M. Abbod M, et al. Pestic Biochem Physiol. 2020 Mar;164:228-236. doi: 10.1016/j.pestbp.2020.02.003. Epub 2020 Feb 4. Pestic Biochem Physiol. 2020. PMID: 32284131
Phytotoxicity of 3-BPH was evident against Lemna minor at 1000 mug /mL; nevertheless, it was nontoxic at the concentrations inhibiting M. phaseolina microsclerotia and dark pigments suggest that it may be safe for use on other plants at low doses. ...
Phytotoxicity of 3-BPH was evident against Lemna minor at 1000 mug /mL; nevertheless, it was nontoxic at the concentrations inhibiting M …
Effects of Plant Growth Hormones on Mucor indicus Growth and Chitosan and Ethanol Production.
Safaei Z, Karimi K, Golkar P, Zamani A. Safaei Z, et al. Int J Mol Sci. 2015 Jul 22;16(7):16683-94. doi: 10.3390/ijms160716683. Int J Mol Sci. 2015. PMID: 26204839 Free PMC article.
In conclusion, IAA and KIN significantly enhanced the M. indicus growth and chitosan production, while at the same time decreasing the ethanol yield to some extent. This study shows that plant growth hormones have a high potential for the improvement of fungal chitosan pro …
In conclusion, IAA and KIN significantly enhanced the M. indicus growth and chitosan production, while at the same time decreasing th …
Obesity and associated lifestyle behaviours in Iran: findings from the First National Non-communicable Disease Risk Factor Surveillance Survey.
Kelishadi R, Alikhani S, Delavari A, Alaedini F, Safaie A, Hojatzadeh E. Kelishadi R, et al. Public Health Nutr. 2008 Mar;11(3):246-51. doi: 10.1017/S1368980007000262. Epub 2007 Jul 12. Public Health Nutr. 2008. PMID: 17625028
The national estimates of overweight, obesity and morbid obesity were 28.6%, 10.8% and 3.4%, respectively. Body mass index (BMI) > or = 25 kg m-2 in men, women, urban residents and rural residents were found in 37%, 48%, 46.7% and 35.5%, respectively. ...
The national estimates of overweight, obesity and morbid obesity were 28.6%, 10.8% and 3.4%, respectively. Body mass index (BMI) > or = 2 …
A Novel Medium for Enhancing Callus Growth of Hazel (Corylus avellana L.).
Salehi M, Moieni A, Safaie N. Salehi M, et al. Sci Rep. 2017 Nov 15;7(1):15598. doi: 10.1038/s41598-017-15703-z. Sci Rep. 2017. PMID: 29142273 Free PMC article.
This modified MS medium increased callus fresh weight (55.8%) as compared to the control. M(10) medium increased fatty acids yield of callus (66.7%) as compared to the control. Liquid M(10) medium maintained growth over a longer period of time and also increased sli …
This modified MS medium increased callus fresh weight (55.8%) as compared to the control. M(10) medium increased fatty acids yield of …
13 results