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Page 1
p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin.
Loonat AA, Martin ED, Sarafraz-Shekary N, Tilgner K, Hertz NT, Levin R, Shokat KM, Burlingame AL, Arabacilar P, Uddin S, Thomas M, Marber MS, Clark JE. Loonat AA, et al. FASEB J. 2019 Dec;33(12):13131-13144. doi: 10.1096/fj.201701545R. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638431 Free PMC article.
In addition, we have identified calpastatin, among other substrates, as a novel direct target of p38gamma that may contribute to the protection observed in p38gammaKO mice.-Loonat, A. A., Martin, E. D., Sarafraz-Shekary, N., Tilgner, K., Hertz, N. T., Levin, R., Shokat, K. …
In addition, we have identified calpastatin, among other substrates, as a novel direct target of p38gamma that may contribute to the protect …
The ratio of concentration of organic carbon and elemental carbon bound to particulate matter in ambient air: a global systematic review and meta-analysis.
Fakhri Y, Sarafraz M, Javid A, Moradi M, Mehri F, Nasiri R, Saadatmandsepideh S. Fakhri Y, et al. Int J Environ Health Res. 2025 Jun;35(6):1596-1615. doi: 10.1080/09603123.2024.2399207. Epub 2024 Sep 10. Int J Environ Health Res. 2025. PMID: 39254320
The rank order of areas based on the pooled concentration of OC bound to PM(2.5) was traffic (17.893 g/m(3)) > industrial (10.58 g/m(3)) > urban (7.696 g/m(3)) > rural (4.08 g/m(3)). The rank order of areas based on the pooled (mean) concentra …
The rank order of areas based on the pooled concentration of OC bound to PM(2.5) was traffic (17.893 g/m(3)) > industrial (10.58 g …
Covert Tracking to Visual Stimuli in Comatose Patients With Traumatic Brain Injury.
Alkhachroum A, Aklepi G, Sarafraz A, Robayo LE, Manolovitz BM, Blandino CF, Arwari B, Sobczak E, Bass DH, Ghamasaee P, Samano D, Massad N, Kottapally M, Merenda A, Dib S, Jagid JR, Dietrich WD, Rundek T, O'Phelan K, Claassen J, Walker MF. Alkhachroum A, et al. Neurology. 2023 Sep 12;101(11):489-494. doi: 10.1212/WNL.0000000000207302. Epub 2023 Apr 19. Neurology. 2023. PMID: 37076304 Free PMC article.
Functional imaging through scattering medium via fluorescence speckle demixing and localization.
Soldevila F, Moretti C, Nöbauer T, Sarafraz H, Vaziri A, Gigan S. Soldevila F, et al. Opt Express. 2023 Jun 19;31(13):21107-21117. doi: 10.1364/OE.487768. Opt Express. 2023. PMID: 37381218 Free PMC article.
We test our approach by imaging the temporal activity of large groups of fluorescent sources behind different scattering phantoms mimicking biological tissues, and through a brain slice with a thickness of 200 m....
We test our approach by imaging the temporal activity of large groups of fluorescent sources behind different scattering phantoms mimicking …
Modelling of mass transport and distribution of aptamer in blood-brain barrier for tumour therapy and cancer treatment.
Sarafraz M, Nakhjavani M, Shigdar S, Christo FC, Rolfe B. Sarafraz M, et al. Eur J Pharm Biopharm. 2022 Apr;173:121-131. doi: 10.1016/j.ejpb.2022.03.004. Epub 2022 Mar 10. Eur J Pharm Biopharm. 2022. PMID: 35283304
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was developed accounting for the fluid flow and mass transport of the aptamer molecule inside an 8 m capillary vessel across a 14 m bloo …
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was develo …
Speckle-enabled in vivo demixing of neural activity in the mouse brain.
Sarafraz H, Nöbauer T, Kim H, Soldevila F, Gigan S, Vaziri A. Sarafraz H, et al. Biomed Opt Express. 2024 May 3;15(6):3586-3608. doi: 10.1364/BOE.524521. eCollection 2024 Jun 1. Biomed Opt Express. 2024. PMID: 38867774 Free PMC article.
In our proof-of-principle experiments, we demonstrate in vivo speckle-assisted demixing of functional signals from groups of sources in a depth range of 220-320 m in mouse cortex, limited by available speckle contrast. Our results serve as a basis for designing an in vivo …
In our proof-of-principle experiments, we demonstrate in vivo speckle-assisted demixing of functional signals from groups of sources in a de …
Prevalence and Concentration of Aflatoxin M1 in Mother Milk: A Meta-analysis, Meta-regression, and Infants' Health Risk Assessment.
Fakhri Y, Ranaei V, Pilevar Z, Sarkhosh M, Sarafraz M, Abdi-Moghadam Z, Javid R. Fakhri Y, et al. J Food Prot. 2025 Feb 26;88(3):100462. doi: 10.1016/j.jfp.2025.100462. Epub 2025 Feb 4. J Food Prot. 2025. PMID: 39914773 Free article. Review.
Breast milk is a complete and nutritious food for newborns and infants, but it may be contaminated with Aflatoxin M(1) (AFM(1)), which endangers consumers' health. Several studies from various regions have determined the concentration and prevalence of AFM(1) in mother mil …
Breast milk is a complete and nutritious food for newborns and infants, but it may be contaminated with Aflatoxin M(1) (AFM(1)), whic …
Molecular evaluation of pvdhfr and pvmdr-1 mutants in Plasmodium vivax isolates after treatment with sulfadoxine/pyrimethamine and chloroquine in Iran during 2001-2016.
Parsaei M, Raeisi A, Spotin A, Shahbazi A, Mahami-Oskouei M, Hazratian T, Khorashad AS, Zaman J, Bazmani A, Sarafraz S. Parsaei M, et al. Infect Genet Evol. 2018 Oct;64:70-75. doi: 10.1016/j.meegid.2018.06.021. Epub 2018 Jun 19. Infect Genet Evol. 2018. PMID: 29929007
Mutations were detected in pvdhfr codons P33L (21.2%), T61 M (25%), S93H (3.9%), and S117 T (1.9%) and 5 isolates showed double mutations (33 L/61 M, 7.7%; 33 L/117 T, 1.9%). ...
Mutations were detected in pvdhfr codons P33L (21.2%), T61 M (25%), S93H (3.9%), and S117 T (1.9%) and 5 isolates showed double mutat …
12 results