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2018 1
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12 results

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Page 1
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression.
Sirpilla O, Sakemura RL, Hefazi M, Huynh TN, Can I, Girsch JH, Tapper EE, Cox MJ, Schick KJ, Manriquez-Roman C, Yun K, Stewart CM, Ogbodo EJ, Kimball BL, Mai LK, Gutierrez-Ruiz OL, Rodriguez ML, Gluscevic M, Larson DP, Abel AM, Wierson WA, Olivier G, Siegler EL, Kenderian SS. Sirpilla O, et al. Nat Biomed Eng. 2024 Apr;8(4):443-460. doi: 10.1038/s41551-024-01195-6. Epub 2024 Apr 1. Nat Biomed Eng. 2024. PMID: 38561490 Free PMC article.
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts.
Sterner RM, Sakemura R, Cox MJ, Yang N, Khadka RH, Forsman CL, Hansen MJ, Jin F, Ayasoufi K, Hefazi M, Schick KJ, Walters DK, Ahmed O, Chappell D, Sahmoud T, Durrant C, Nevala WK, Patnaik MM, Pease LR, Hedin KE, Kay NE, Johnson AJ, Kenderian SS. Sterner RM, et al. Blood. 2019 Feb 14;133(7):697-709. doi: 10.1182/blood-2018-10-881722. Epub 2018 Nov 21. Blood. 2019. PMID: 30463995 Free PMC article.
CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS.
Sakemura RL, Manriquez Roman C, Horvei P, Siegler EL, Girsch JH, Sirpilla OL, Stewart CM, Yun K, Can I, Ogbodo EJ, Adada MM, Bezerra ED, Kankeu Fonkoua LA, Hefazi M, Ruff MW, Kimball BL, Mai LK, Huynh TN, Nevala WK, Ilieva K, Augsberger C, Patra-Kneuer M, Schanzer J, Endell J, Heitmüller C, Steidl S, Parikh SA, Ding W, Kay NE, Nowakowski GS, Kenderian SS. Sakemura RL, et al. Blood. 2024 Jan 18;143(3):258-271. doi: 10.1182/blood.2022018905. Blood. 2024. PMID: 37879074 Free PMC article.
Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease.
Ma L, Koehn B, Zaiken M, Hippen KL, Smith K, Allred J, Williams R, Yao K, Fink J, Saha A, Koop B, Payne N, Widelak R, Panoskaltsis-Mortari A, Riddle MJ, Tolar J, Eide C, Xia L, Witty AD, Mehta AK, Denholtz M, Hefazi M, Hani S, Kenderian SS, Miller JS, Molldrem JJ, Kean LS, Valamehr B, Blazar BR. Ma L, et al. Blood. 2025 Oct 23;146(17):2047-2062. doi: 10.1182/blood.2025028562. Blood. 2025. PMID: 40700578
Intrinsic immunosuppressive features of monocytes suppress CAR-T19 through IL-1 pathway modulation in mantle cell lymphoma.
Yun K, Sakemura RL, Can I, Gutierrez Ruiz O, Ogbodo EJ, Zhang S, Saleh A, Huynh TN, Manriquez Roman C, Sirpilla OL, Stewart CM, Girsch JH, Feigin JM, Mai L, Xia H, Kimball B, Kankeu Fonkoua LA, Hefazi M, Ruff MW, Rohakhtar FR, Simon V, Siegler EL, Mattie M, Nguyen-Mau SM, Filosto S, Kenderian SS. Yun K, et al. Mol Ther Oncol. 2025 Apr 19;33(2):200985. doi: 10.1016/j.omton.2025.200985. eCollection 2025 Jun 18. Mol Ther Oncol. 2025. PMID: 40458688 Free PMC article.
Factors associated with survival after allogeneic transplantation for myeloid neoplasms harboring TP53 mutations.
Baranwal A, Langer KJ, Gannamani V, Rud D, Cibich A, Saygin C, Nawas M, Badar T, Kharfan-Dabaja MA, Ayala E, Roy V, Foran JM, Murthy HS, Iqbal M, Palmer J, Sproat LZ, Chhabra S, Khera N, Hefazi M, Mangaonkar A, Hogan W, Litzow M, Alkhateeb H, Tefferi A, Kok CH, Guru Murthy GS, Patel A, Bajel A, Hiwase DK, Shah MV. Baranwal A, et al. Blood Adv. 2025 Jul 22;9(14):3395-3407. doi: 10.1182/bloodadvances.2024015335. Blood Adv. 2025. PMID: 40085959 Free PMC article.
Clinical Outcomes and Treatment Strategies of Adult Transplant-Associated Thrombotic Microangiopathy: External Validation of Harmonizing Definitions and High-Risk Criteria.
Acosta-Medina AA, Sridharan M, Go RS, Moyer AM, Leung N, Willrich MAV, Wolf R, Kassis R, Manasrah A, Kohorst MA, Durani U, Matin A, Hefazi M, Kenderian SJ, Mangaonkar AA, Shah MV, Litzow MR, Hogan WJ, Dingli D, Alkhateeb HB. Acosta-Medina AA, et al. Am J Hematol. 2025 May;100(5):830-839. doi: 10.1002/ajh.27651. Epub 2025 Mar 6. Am J Hematol. 2025. PMID: 40047384 Free PMC article.
Validation of the 5th edition of the World Health Organization and International Consensus Classification guidelines for TP53-mutated myeloid neoplasm in an independent international cohort.
Shah MV, Hung K, Baranwal A, Wechalekar G, Al-Kali A, Toop CR, Greipp P, Kutyna MM, Matin A, Ladon D, Saliba A, Chen D, Begna K, Brown A, Rud D, Litzow MR, Hogan WJ, Bardy P, Badar T, Kumar S, Yeung DT, Patnaik MM, Foran JM, He R, Gangat N, Hefazi M, Scott HS, Arana Yi CY, Alkhateeb H, Mangaonkar AA, Thomas D, Hahn CN, Orazi A, Arber DA, Kok CH, Tefferi A, Hiwase D. Shah MV, et al. Blood Cancer J. 2025 May 7;15(1):88. doi: 10.1038/s41408-025-01290-0. Blood Cancer J. 2025. PMID: 40335478 Free PMC article.
Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia.
Cox MJ, Lucien F, Sakemura R, Boysen JC, Kim Y, Horvei P, Manriquez Roman C, Hansen MJ, Tapper EE, Siegler EL, Forsman C, Crotts SB, Schick KJ, Hefazi M, Ruff MW, Can I, Adada M, Bezerra E, Kankeu Fonkoua LA, Nevala WK, Braggio E, Ding W, Parikh SA, Kay NE, Kenderian SS. Cox MJ, et al. Mol Ther. 2021 Apr 7;29(4):1529-1540. doi: 10.1016/j.ymthe.2020.12.033. Epub 2021 Jan 1. Mol Ther. 2021. PMID: 33388419 Free PMC article.
Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia.
Mangaonkar AA, Reichard KK, Binder M, Coltro G, Lasho TL, Carr RM, Chiu A, Negron V, Hefazi M, Anagnostou T, Timm MM, Hiebert JW, Villasboas JC, Gonsalves WI, Gangat N, Shah M, Alkhateeb HB, Al-Kali A, Elliott MA, Begna KH, Wolanskyj-Spinner AP, Litzow MR, Hogan WJ, Ansell SM, Pardanani A, Tefferi A, Patnaik MM. Mangaonkar AA, et al. Blood Adv. 2020 Nov 10;4(21):5425-5430. doi: 10.1182/bloodadvances.2020002415. Blood Adv. 2020. PMID: 33152058 Free PMC article.
12 results