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Year Number of Results
1960 1
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1964 1
1969 1
1973 3
1975 12
1976 6
1977 7
1978 10
1979 10
1980 8
1981 14
1982 21
1983 16
1984 17
1985 17
1986 25
1987 28
1988 35
1989 36
1990 59
1991 48
1992 71
1993 62
1994 108
1995 100
1996 105
1997 107
1998 116
1999 123
2000 183
2001 176
2002 230
2003 255
2004 320
2005 368
2006 408
2007 437
2008 490
2009 536
2010 654
2011 823
2012 947
2013 1060
2014 1366
2015 1495
2016 1708
2017 1802
2018 2193
2019 2588
2020 2960
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2023 3955
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2025 2850

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36,309 results

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Page 1
YTHDF3 Induces the Translation of m(6)A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis.
Chang G, Shi L, Ye Y, Shi H, Zeng L, Tiwary S, Huse JT, Huo L, Ma L, Ma Y, Zhang S, Zhu J, Xie V, Li P, Han L, He C, Huang S. Chang G, et al. Cancer Cell. 2020 Dec 14;38(6):857-871.e7. doi: 10.1016/j.ccell.2020.10.004. Epub 2020 Oct 29. Cancer Cell. 2020. PMID: 33125861 Free PMC article.
In addition, little is known regarding the role of m(6)A reader YTHDF3 in human diseases. Here, we show that YTHDF3 overexpression clinically correlates with brain metastases in breast cancer patients. ...Mechanistically, YTHDF3 enhances the translation of m(6)A-enr …
In addition, little is known regarding the role of m(6)A reader YTHDF3 in human diseases. Here, we show that YTHDF3 overexpression cl …
Simultaneous nanopore profiling of mRNA m(6)A and pseudouridine reveals translation coordination.
Huang S, Wylder AC, Pan T. Huang S, et al. Nat Biotechnol. 2024 Dec;42(12):1831-1835. doi: 10.1038/s41587-024-02135-0. Epub 2024 Feb 6. Nat Biotechnol. 2024. PMID: 38321115
N6-methyladenosine (m(6)A) and pseudouridine (psi) are the two most abundant modifications in mammalian messenger RNA, but the coordination of their biological functions remains poorly understood. We develop a machine learning-based nanopore direct RNA sequencing method (N …
N6-methyladenosine (m(6)A) and pseudouridine (psi) are the two most abundant modifications in mammalian messenger RNA, but the coordi …
Correction.
[No authors listed] [No authors listed] FEBS Open Bio. 2024 Dec;14(12):2118. doi: 10.1002/2211-5463.13928. Epub 2024 Nov 21. FEBS Open Bio. 2024. PMID: 39569529 Free PMC article.
Information regarding the coauthor Ying-Fei Huang's non-involvement with the research and writing of this article was erroneously missed in the above retraction notice and has been included in this version. ...Thus, the editors consider the conclusions of this manus …
Information regarding the coauthor Ying-Fei Huang's non-involvement with the research and writing of this article was erroneou …
The Roles and Regulation of m(6)A Modification in Glioblastoma Stem Cells and Tumorigenesis.
Li P, Richard HT, Zhu K, Li L, Huang S. Li P, et al. Biomedicines. 2022 Apr 22;10(5):969. doi: 10.3390/biomedicines10050969. Biomedicines. 2022. PMID: 35625706 Free PMC article. Review.
Accumulated evidence demonstrates that m(6)A modification is aberrantly activated in human cancers and is critical for tumorigenesis and metastasis. m(6)A modification is also strongly involved in key signaling pathways and is associated with prognosis in glioblasto …
Accumulated evidence demonstrates that m(6)A modification is aberrantly activated in human cancers and is critical for tumorigenesis …
ZFHX3 acts as a tumor suppressor in prostate cancer by targeting FTO-mediated m(6)A demethylation.
Hu Q, Yin J, Zhao S, Wang Y, Shi R, Yan K, Huang S. Hu Q, et al. Cell Death Discov. 2024 Jun 13;10(1):284. doi: 10.1038/s41420-024-02060-w. Cell Death Discov. 2024. PMID: 38871709 Free PMC article.
However, the underlying molecular function of ZFHX3 during prostatic tumorigenesis is not well understood. N(6)-methyladenosine (m(6)A) modification in RNA plays a critical role in the development of cancers; however, the relationship between ZFHX3 and m(6)A modific …
However, the underlying molecular function of ZFHX3 during prostatic tumorigenesis is not well understood. N(6)-methyladenosine (m(6) …
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
Huang S, Cao C, Tang D, Liu Y, Zhou W, Liu L, Zheng X, He Q, Wang A. Huang S, et al. Biomedicines. 2024 Nov 6;12(11):2533. doi: 10.3390/biomedicines12112533. Biomedicines. 2024. PMID: 39595099 Free PMC article.
Recent research highlights the role of 5-methylcytosine (m(5)C) in cancer progression. NSUN2, an m(5)C methyltransferase, has been implicated in various cancers, but its role in HNSCC remains elusive. METHODS: NSUN2 expression and its impact on HNSCC were analyzed b …
Recent research highlights the role of 5-methylcytosine (m(5)C) in cancer progression. NSUN2, an m(5)C methyltransferase, has …
Biomedical informatics with optimization and machine learning.
Huang S, Zhou J, Wang Z, Ling Q, Shen Y. Huang S, et al. EURASIP J Bioinform Syst Biol. 2017 Feb 8;2017:4. doi: 10.1186/s13637-017-0058-0. eCollection 2017 Dec. EURASIP J Bioinform Syst Biol. 2017. PMID: 28246526 Free PMC article. No abstract available.
Methylation of RNA N6-methyladenosine in modulation of cytokine responses and tumorigenesis.
Chang G, Leu JS, Ma L, Xie K, Huang S. Chang G, et al. Cytokine. 2019 Jun;118:35-41. doi: 10.1016/j.cyto.2018.06.018. Epub 2018 Jul 13. Cytokine. 2019. PMID: 30017390 Review.
Among myriads of distinct chemical modification in RNAs, the dynamic, reversible and fine-tuned methylation of N(6)-methyladenosine (m(6)A) is the most prevalent modification in eukaryotic mRNAs. This RNA mark is generated by proteins that act as m(6)A writers and c …
Among myriads of distinct chemical modification in RNAs, the dynamic, reversible and fine-tuned methylation of N(6)-methyladenosine (m
36,309 results
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