M-Sec induced by HTLV-1 mediates an efficient viral transmission.
Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.
Hiyoshi M, et al.
PLoS Pathog. 2021 Nov 29;17(11):e1010126. doi: 10.1371/journal.ppat.1010126. eCollection 2021 Nov.
PLoS Pathog. 2021.
PMID: 34843591
Free PMC article.
Here, we provide evidence that cellular protein M-Sec plays a critical role in this process. When purified and briefly cultured, CD4+ T cells of HTLV-1 carriers, but not of HTLV-1- individuals, expressed M-Sec. The viral protein Tax was revealed to mediate M- …
Here, we provide evidence that cellular protein M-Sec plays a critical role in this process. When purified and briefly cultured, CD4+ …