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4,301 results

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Page 1
RNA m(6)A modification orchestrates the rhythm of immune cell development from hematopoietic stem cells to T and B cells.
Zhao C, Xu G, Zhang X, Ye Y, Cai W, Shao Q. Zhao C, et al. Front Immunol. 2022 Jul 22;13:839291. doi: 10.3389/fimmu.2022.839291. eCollection 2022. Front Immunol. 2022. PMID: 35935968 Free PMC article. Review.
To date, hundreds of different RNA modifications have been identified. N6-methyladenosine (m(6)A) is one of the most important RNA modifications in mammalian cells. An increasing body of evidence from recently published studies suggests that m(6)A modification is a …
To date, hundreds of different RNA modifications have been identified. N6-methyladenosine (m(6)A) is one of the most important RNA mo …
NERD-dependent m(6)A modification of the nascent FLC transcript regulates flowering time in Arabidopsis.
Shao Y, Ma J, Zhang S, Xu Y, Yu H. Shao Y, et al. Nat Plants. 2025 Mar;11(3):468-482. doi: 10.1038/s41477-025-01945-7. Epub 2025 Mar 14. Nat Plants. 2025. PMID: 40087542
N(6)-methyladenosine (m(6)A) is the most prevalent internal modification on messenger RNA. Although recent studies have shown m(6)A effects on determining the fate of mRNA through modulating various aspects of plant mRNA metabolism, whether and how m(6)A affe …
N(6)-methyladenosine (m(6)A) is the most prevalent internal modification on messenger RNA. Although recent studies have shown m …
N6-methyladenosine modification underlies messenger RNA metabolism and plant development.
Shao Y, Wong CE, Shen L, Yu H. Shao Y, et al. Curr Opin Plant Biol. 2021 Oct;63:102047. doi: 10.1016/j.pbi.2021.102047. Epub 2021 May 6. Curr Opin Plant Biol. 2021. PMID: 33965696 Review.
As the most prevalent internal modification on eukaryotic mRNAs, N(6)-methyladenosine (m(6)A) exists in many plant species and requires the evolutionarily conserved methyltransferases, demethylases, and m(6)A binding proteins for writing, erasing, and reading m …
As the most prevalent internal modification on eukaryotic mRNAs, N(6)-methyladenosine (m(6)A) exists in many plant species and requir …
Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiation.
Luo H, Liu W, Zhou Y, Zhang Y, Wu J, Wang R, Shao L. Luo H, et al. J Transl Med. 2022 Dec 16;20(1):605. doi: 10.1186/s12967-022-03814-9. J Transl Med. 2022. PMID: 36527141 Free PMC article.
The present study focuses on the biological function and mechanism of m(6)A methylation in dental pulp stem cell (DPSC) differentiation. METHODS: m(6)A RNA immunoprecipitation sequencing was utilized to assess the m(6)A-mRNA landscape during DPSC differentiat …
The present study focuses on the biological function and mechanism of m(6)A methylation in dental pulp stem cell (DPSC) differentiati …
METTL3-mediated m(6)A modification regulates cell cycle progression of dental pulp stem cells.
Luo H, Liu W, Zhang Y, Yang Y, Jiang X, Wu S, Shao L. Luo H, et al. Stem Cell Res Ther. 2021 Mar 1;12(1):159. doi: 10.1186/s13287-021-02223-x. Stem Cell Res Ther. 2021. PMID: 33648590 Free PMC article.
In this study, we aim to explore the biological effect of m(6)A methylation in DPSCs. METHODS: m(6)A immunoprecipitation with deep sequencing (m(6)A RIP-seq) demonstrated the features of m(6)A modifications in DPSC transcriptome. ...Cell cycle distribu …
In this study, we aim to explore the biological effect of m(6)A methylation in DPSCs. METHODS: m(6)A immunoprecipitation with …
The momentous role of N6-methyladenosine in lung cancer.
Xu R, Pang G, Zhao Q, Yang L, Chen S, Jiang L, Shen Y, Shao W. Xu R, et al. J Cell Physiol. 2021 May;236(5):3244-3256. doi: 10.1002/jcp.30136. Epub 2020 Nov 1. J Cell Physiol. 2021. PMID: 33135190 Review.
Ectopic m(6) A modification is associated with human carcinogenesis, including lung cancer. ...This review summarizes recent studies on the biological functions of the m(6) A modification in lung cancer and discusses the potential application of m(6) A regula …
Ectopic m(6) A modification is associated with human carcinogenesis, including lung cancer. ...This review summarizes recent studies …
The effects and mechanisms of chai shao jie yu granules on chronic unpredictable mild stress (CUMS)-induced depressive rats based on network pharmacology.
Tang Q, Chu H, Sun N, Fan X, Han B, Li Y, Yu X, Li L, Wang X, Liu L, Chang H. Tang Q, et al. J Ethnopharmacol. 2025 Jan 31;340:119268. doi: 10.1016/j.jep.2024.119268. Epub 2024 Dec 18. J Ethnopharmacol. 2025. PMID: 39706355 Free article.
ETHNOPHARMACOLOGICAL RELEVANCE: Chai Shao Jie Yu Granules (CSJY) is a renowned and time-honored formula employed in clinical practice for the management of various conditions, notably depression. ...MATERIALS AND METHODS: Rat models of CUMS-induced depression were establis …
ETHNOPHARMACOLOGICAL RELEVANCE: Chai Shao Jie Yu Granules (CSJY) is a renowned and time-honored formula employed in clinical practice …
Expression of divergent methyl/alkyl coenzyme M reductases from uncultured archaea.
Shao N, Fan Y, Chou CW, Yavari S, Williams RV, Amster IJ, Brown SM, Drake IJ, Duin EC, Whitman WB, Liu Y. Shao N, et al. Commun Biol. 2022 Oct 20;5(1):1113. doi: 10.1038/s42003-022-04057-6. Commun Biol. 2022. PMID: 36266535 Free PMC article.
Methanogens and anaerobic methane-oxidizing archaea (ANME) are important players in the global carbon cycle. Methyl-coenzyme M reductase (MCR) is a key enzyme in methane metabolism, catalyzing the last step in methanogenesis and the first step in anaerobic methane oxidatio …
Methanogens and anaerobic methane-oxidizing archaea (ANME) are important players in the global carbon cycle. Methyl-coenzyme M reduct …
Commentary on "ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients." Baena E, Shao Z, Linn DE, Glass K, Hamblen MJ, Fujiwara Y, Kim J, Nguyen M, Zhang X, Godinho FJ, Bronson RT, Mucci LA, Loda M, Yuan GC, Orkin SH, Li Z, Division of Hematology and Oncology, Boston Children's Hospital, Boston, MA, USA.: Genes Dev 2013;27(6):683-98.
Olumi AF. Olumi AF. Urol Oncol. 2014 Feb;32(2):213. doi: 10.1016/j.urolonc.2013.08.016. Urol Oncol. 2014. PMID: 24445296
4,301 results