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56 results

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Page 1
Mycobacterium tuberculosis: The Mechanism of Pathogenicity, Immune Responses, and Diagnostic Challenges.
Mohammadnabi N, Shamseddin J, Emadi M, Bodaghi AB, Varseh M, Shariati A, Rezaei M, Dastranj M, Farahani A. Mohammadnabi N, et al. J Clin Lab Anal. 2024 Dec;38(23):e25122. doi: 10.1002/jcla.25122. Epub 2024 Nov 26. J Clin Lab Anal. 2024. PMID: 39593272 Free PMC article. Review.
One reason why this study is significant is the lack of a comprehensive review in this field that thoroughly examines the importance, pathogenesis, and diagnosis of M. tuberculosis. Therefore, the aim of this review is to provide updated information on M. tuberculos …
One reason why this study is significant is the lack of a comprehensive review in this field that thoroughly examines the importance, pathog …
Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies.
Jayedi A, Khan TA, Aune D, Emadi A, Shab-Bidar S. Jayedi A, et al. Int J Obes (Lond). 2022 Sep;46(9):1573-1581. doi: 10.1038/s41366-022-01165-5. Epub 2022 Jun 18. Int J Obes (Lond). 2022. PMID: 35717418
The HRs were 1.06 (95%CI: 1.01, 1.12; I(2) = 86%, n = 10) for a 5 kg increment in FM, 1.11 (95%CI: 1.06, 1.16; I(2) = 79%, n = 7) for a 2 kg/m(2) increment in FMI, and 1.17 (95%CI: 1.03, 1.33; I(2) = 72%, n = 8) and 0.81 (0.66, 0.99; I(2) = 59%, n = 6) for a 1-SD increment …
The HRs were 1.06 (95%CI: 1.01, 1.12; I(2) = 86%, n = 10) for a 5 kg increment in FM, 1.11 (95%CI: 1.06, 1.16; I(2) = 79%, n = 7) for a 2 kg …
Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia.
Uy GL, Aldoss I, Foster MC, Sayre PH, Wieduwilt MJ, Advani AS, Godwin JE, Arellano ML, Sweet KL, Emadi A, Ravandi F, Erba HP, Byrne M, Michaelis L, Topp MS, Vey N, Ciceri F, Carrabba MG, Paolini S, Huls GA, Jongen-Lavrencic M, Wermke M, Chevallier P, Gyan E, Récher C, Stiff PJ, Pettit KM, Löwenberg B, Church SE, Anderson E, Vadakekolathu J, Santaguida M, Rettig MP, Muth J, Curtis T, Fehr E, Guo K, Zhao J, Bakkacha O, Jacobs K, Tran K, Kaminker P, Kostova M, Bonvini E, Walter RB, Davidson-Moncada JK, Rutella S, DiPersio JF. Uy GL, et al. Blood. 2021 Feb 11;137(6):751-762. doi: 10.1182/blood.2020007732. Blood. 2021. PMID: 32929488 Free PMC article. Clinical Trial.
Equipotent doses of daunorubicin and idarubicin for AML: a meta-analysis of clinical trials versus in vitro estimation.
Adige S, Lapidus RG, Carter-Cooper BA, Duffy A, Patzke C, Law JY, Baer MR, Ambulos NP, Zou Y, Bentzen SM, Emadi A. Adige S, et al. Cancer Chemother Pharmacol. 2019 Jun;83(6):1105-1112. doi: 10.1007/s00280-019-03825-2. Epub 2019 Apr 9. Cancer Chemother Pharmacol. 2019. PMID: 30968179 Free PMC article. Review.
In the treatment of acute myeloid leukemia (AML), the "7 + 3"-based strategy, combining cytarabine 100-200 mg/m(2) for 7 days with an anthracycline for 3 days, remains the standard of care for younger and medically fit patients. ...
In the treatment of acute myeloid leukemia (AML), the "7 + 3"-based strategy, combining cytarabine 100-200 mg/m(2) for 7 days with an …
Increased body mass index is a risk factor for acute promyelocytic leukemia.
Kashanian SM, Li AY, Mustafa Ali M, Sutherland ME, Duong VH, Hambley BC, Zacholski K, El Chaer F, Holtzman NG, Imran M, Patzke CL, Cornu J, Duffy A, Dezern AE, Gojo I, Norsworthy KJ, Levis MJ, Smith BD, Baer MR, Ghiaur G, Emadi A. Kashanian SM, et al. EJHaem. 2021 Feb;2(1):33-39. doi: 10.1002/jha2.163. Epub 2021 Jan 6. EJHaem. 2021. PMID: 33693438 Free PMC article.
RESULTS: Patients with APL had a significantly higher unadjusted mean and median BMI (32.5 kg/m(2) and 30.3 kg/m(2)) than those with AML (28.3 kg/m(2) and 27.1 kg/m(2)), ALL (29.3 kg/m(2) and 27.7 kg/m(2)), and others (29.3 kg/m(2) …
RESULTS: Patients with APL had a significantly higher unadjusted mean and median BMI (32.5 kg/m(2) and 30.3 kg/m(2)) than thos …
Synthesis and biological assessment of ciprofloxacin-derived 1,3,4-thiadiazoles as anticancer agents.
Ahadi H, Shokrzadeh M, Hosseini-Khah Z, Ghassemi Barghi N, Ghasemian M, Emadi E, Zargari M, Razzaghi-Asl N, Emami S. Ahadi H, et al. Bioorg Chem. 2020 Dec;105:104383. doi: 10.1016/j.bioorg.2020.104383. Epub 2020 Oct 15. Bioorg Chem. 2020. PMID: 33130342
In particular, compounds 13a-e and 13g were found to be as potent as standard drug doxorubicin against MCF-7 cell line (IC(50)s = 3.26-3.90 M). Furthermore, the 4-fluorobenzyl derivatives 13h and 14b with IC(50) values of 3.58 and 2.79 M exhibited the highest acti …
In particular, compounds 13a-e and 13g were found to be as potent as standard drug doxorubicin against MCF-7 cell line (IC(50)s = 3.26-3.90 …
Comparison of High-Dose Cytarabine, Mitoxantrone, and Pegaspargase (HAM-pegA) to High-Dose Cytarabine, Mitoxantrone, Cladribine, and Filgrastim (CLAG-M) as First-Line Salvage Cytotoxic Chemotherapy for Relapsed/Refractory Acute Myeloid Leukemia.
Patzke CL, Duffy AP, Duong VH, El Chaer F, Trovato JA, Baer MR, Bentzen SM, Emadi A. Patzke CL, et al. J Clin Med. 2020 Feb 16;9(2):536. doi: 10.3390/jcm9020536. J Clin Med. 2020. PMID: 32079074 Free PMC article.
We present our institutional experience with using either CLAG-M or HAM-pegA, a novel regimen that includes pegaspargase. This is a retrospective comparison of 34 patients receiving CLAG-M and 10 receiving HAM-pegA as first salvage cytotoxic chemotherapy in the rela …
We present our institutional experience with using either CLAG-M or HAM-pegA, a novel regimen that includes pegaspargase. This is a r …
Determination of genetic relationship between environmental Escherichia coli with PFGE and investigation of IS element in bla(CTX-M) gene of these isolates.
Valizadeh S, Yousefi B, Abdolshahi A, Emadi A, Eslami M. Valizadeh S, et al. Microb Pathog. 2021 Oct;159:105154. doi: 10.1016/j.micpath.2021.105154. Epub 2021 Aug 19. Microb Pathog. 2021. PMID: 34419612
The bla(CTX-M) producing E. coli and IS element of this gene with phylogenetic typing were detected by PCR. ...The majority of isolates were resistant to cefotaxime and ceftazidime antibiotics and also phosphomycin antibiotic resistant were detected in 10% of isolates. CTX …
The bla(CTX-M) producing E. coli and IS element of this gene with phylogenetic typing were detected by PCR. ...The majority of isolat …
56 results