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18 results

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Page 1
Association of hypertension with infection and inflammation in a setting of disadvantage in rural India.
Busingye D, Evans RG, Arabshahi S, Riddell MA, Srikanth VK, Kartik K, Kalyanram K, Zhu X, Suresh O, Thrift AG. Busingye D, et al. J Hum Hypertens. 2022 Nov;36(11):1011-1020. doi: 10.1038/s41371-021-00609-1. Epub 2021 Sep 17. J Hum Hypertens. 2022. PMID: 34535756
In multivariable conditional logistic regression, elevated homocysteine (OR 1.75, 95% CI 1.09-2.82), greater lymphocyte count (OR 1.49, 95% CI 1.01-2.01) and exposure to fecal contamination, defined as a distance from the field used for toilet purposes to the household of 50 m …
In multivariable conditional logistic regression, elevated homocysteine (OR 1.75, 95% CI 1.09-2.82), greater lymphocyte count (OR 1.49, 95% …
Galactose mutarotase: pH dependence of enzymatic mutarotation.
Beebe JA, Arabshahi A, Clifton JG, Ringe D, Petsko GA, Frey PA. Beebe JA, et al. Biochemistry. 2003 Apr 22;42(15):4414-20. doi: 10.1021/bi020639a. Biochemistry. 2003. PMID: 12693937
Here we report pH dependence of kinetic parameters for the mutarotation of alpha-D-glucose catalyzed by galactose mutarotase (GalM) from Escherichia coli. The values of k(cat) and k(cat)/K(m) for the mutarotation of alpha-D-galactose were found to be 1.84 x 10(4) s(-1) and …
Here we report pH dependence of kinetic parameters for the mutarotation of alpha-D-glucose catalyzed by galactose mutarotase (GalM) from Esc …
Renal and dietary factors associated with hypertension in a setting of disadvantage in rural India.
Evans RG, Subasinghe AK, Busingye D, Srikanth VK, Kartik K, Kalyanram K, Suresh O, Arabshahi S, Curkpatrick I, O'Dea K, Walker KZ, Kaye M, Yang J, Thomas N, Arulappan G, Thrift AG. Evans RG, et al. J Hum Hypertens. 2021 Dec;35(12):1118-1128. doi: 10.1038/s41371-020-00473-5. Epub 2021 Jan 18. J Hum Hypertens. 2021. PMID: 33462389
Underweight (29%, body mass index < 18.0 kg m(-2)), chronic kidney disease (25%, estimated glomerular filtration rate <60 ml min(-1) 1.73 m(-2)) and anemia (82%) were highly prevalent. ...

Underweight (29%, body mass index < 18.0 kg m(-2)), chronic kidney disease (25%, estimated glomerular filtration rate <60 ml mi

…
Comprehensive profiling of prostaglandins in human ovarian follicular fluid using mass spectrometry.
Pier B, Edmonds JW, Wilson L, Arabshahi A, Moore R, Bates GW, Prasain JK, Miller MA. Pier B, et al. Prostaglandins Other Lipid Mediat. 2018 Jan;134:7-15. doi: 10.1016/j.prostaglandins.2017.11.001. Epub 2017 Nov 9. Prostaglandins Other Lipid Mediat. 2018. PMID: 29129796 Free PMC article.
Other than PGF2alpha, only body mass index >25kg/m(2) correlated with poor in vitro fertilization outcome. Our studies suggest that HFF contains prostaglandins formed from at least two mechanisms, which may correlate with distinct clinical parameters....
Other than PGF2alpha, only body mass index >25kg/m(2) correlated with poor in vitro fertilization outcome. Our studies suggest tha …
Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening.
Mamontova EM, Zakharenko AL, Zakharova OD, Dyrkheeva NS, Volcho KP, Reynisson J, Arabshahi HJ, Salakhutdinov NF, Lavrik OI. Mamontova EM, et al. Bioorg Med Chem. 2020 Jan 1;28(1):115234. doi: 10.1016/j.bmc.2019.115234. Epub 2019 Nov 30. Bioorg Med Chem. 2020. PMID: 31831297
Six compounds showed activity with IC(50) values between 3.5 and 25.1 M. The most active ligand 5 (3.5 M) is a dicoumarin followed by a close structural analogue 6 at 6.0 M. ...
Six compounds showed activity with IC(50) values between 3.5 and 25.1 M. The most active ligand 5 (3.5 M) is a dicoumarin foll …
Combining general and central measures of adiposity to identify risk of hypertension: a cross-sectional survey in rural India.
Ragavan RS, Ismail J, Evans RG, Srikanth VK, Kaye M, Joshi R, Thankappan KR, Chow CK, Riddell MA, Oldenburg B, Mahal A, Kalyanram K, Kartik K, Suresh O, Thomas N, Mini GK, Maulik PK, Arabshahi S, Thrift AG. Ragavan RS, et al. Obes Res Clin Pract. 2023 May-Jun;17(3):249-256. doi: 10.1016/j.orcp.2023.04.005. Epub 2023 May 2. Obes Res Clin Pract. 2023. PMID: 37142499
Large proportions were overweight as defined by body mass index (BMI) 23 kg/m(2) (47.7 %), waist circumference (WC) 90 cm for men or 80 cm for women (39.6 %), waist-hip ratio (WHR) 0.9 for men or 0.8 for women (65.6 %), waist-height ratio (WHtR) 0.5 (62.5 %), or by BMI plu …
Large proportions were overweight as defined by body mass index (BMI) 23 kg/m(2) (47.7 %), waist circumference (WC) 90 cm for men or …
Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.
Salomatina OV, Popadyuk II, Zakharenko AL, Zakharova OD, Fadeev DS, Komarova NI, Reynisson J, Arabshahi HJ, Chand R, Volcho KP, Salakhutdinov NF, Lavrik OI. Salomatina OV, et al. Molecules. 2018 Mar 17;23(3):679. doi: 10.3390/molecules23030679. Molecules. 2018. PMID: 29562592 Free PMC article.
In vitro studies demonstrate the ability of the semisynthetic derivatives to effectively inhibit Tdp1 with IC(50) up to 0.29 M. Furthermore, an excellent fit is realized for the ligands when docked into the active site of the Tdp1 enzyme....
In vitro studies demonstrate the ability of the semisynthetic derivatives to effectively inhibit Tdp1 with IC(50) up to 0.29 M. Furth …
Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract.
Prasain JK, Peng N, Dai Y, Moore R, Arabshahi A, Wilson L, Barnes S, Michael Wyss J, Kim H, Watts RL. Prasain JK, et al. Phytomedicine. 2009 Mar;16(2-3):233-43. doi: 10.1016/j.phymed.2008.08.006. Epub 2008 Dec 17. Phytomedicine. 2009. PMID: 19095430 Free PMC article.
A new tetramethylated metabolite of dimeric proanthocyanidin (m/z 633) in GSE-treated urine was tentatively identified. Using LC-MS/MS, (+)-catechin and (-)-epicatechin were identified in the brain conclusively. ...
A new tetramethylated metabolite of dimeric proanthocyanidin (m/z 633) in GSE-treated urine was tentatively identified. Using LC-MS/M …
18 results