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Haplotype-based stratification of Huntington's disease.
Chao MJ, Gillis T, Atwal RS, Mysore JS, Arjomand J, Harold D, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. Chao MJ, et al. Eur J Hum Genet. 2017 Nov;25(11):1202-1209. doi: 10.1038/ejhg.2017.125. Epub 2017 Aug 23. Eur J Hum Genet. 2017. PMID: 28832564 Free PMC article.
Deletion of loop fragment adjacent to active site diminishes the stability and activity of exo-inulinase.
Arjomand MR, Habibi-Rezaei M, Ahmadian G, Hassanzadeh M, Karkhane AA, Asadifar M, Amanlou M. Arjomand MR, et al. Int J Biol Macromol. 2016 Nov;92:1234-1241. doi: 10.1016/j.ijbiomac.2016.08.039. Epub 2016 Aug 12. Int J Biol Macromol. 2016. PMID: 27527695
Evaluation of the kinetics parameters (V(max), K(m), k(cat) and, k(cat)/K(m)) and activation energy (E(a)) of the catalysis of enzymes indicated the importance of the deleted sequence on the catalytic performance of the enzyme. ...
Evaluation of the kinetics parameters (V(max), K(m), k(cat) and, k(cat)/K(m)) and activation energy (E(a)) of the catalysis of …