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O-prenylated carbostyrils as a novel class of 15-lipoxygenase inhibitors: Synthesis, characterization, and inhibitory assessment.
Alavi SJ, Zebarjadi A, Bafghi MH, Orafai H, Sadeghian H. Alavi SJ, et al. Chem Biol Drug Des. 2021 Nov;98(5):894-902. doi: 10.1111/cbdd.13944. Epub 2021 Sep 5. Chem Biol Drug Des. 2021. PMID: 34453501
Among all of the synthetic compounds (coumarin and carbostyril derivatives), 5-farnesyloxycoumarin and 8-farnesyloxycarbostyril demonstrated the best inhibitory activity by IC(50) values of 1.1 M and 0.53 M, respectively....
Among all of the synthetic compounds (coumarin and carbostyril derivatives), 5-farnesyloxycoumarin and 8-farnesyloxycarbostyril demonstrated …
Biophysical aspects of submaximal hand cycling.
Bafghi HA, de Haan A, Horstman A, van der Woude L. Bafghi HA, et al. Int J Sports Med. 2008 Aug;29(8):630-8. doi: 10.1055/s-2007-989416. Epub 2008 Jan 22. Int J Sports Med. 2008. PMID: 18213544
Mean power output was 35.4 +/- 7 W (v = 2.78 m/s). At this speed oxygen uptake was 1.11 +/- 0.25 and 1.26 +/- 0.26 l/min for the synchronous and asynchronous modes, respectively. Mechanical efficiency was significantly higher (v = 2.78 m/s: + 11.5 %) in synchronous …
Mean power output was 35.4 +/- 7 W (v = 2.78 m/s). At this speed oxygen uptake was 1.11 +/- 0.25 and 1.26 +/- 0.26 l/min for the sync …
Power output and metabolic cost of synchronous and asynchronous submaximal and peak level hand cycling on a motor driven treadmill in able-bodied male subjects.
van der Woude LH, Horstman A, Faas P, Mechielsen S, Bafghi HA, de Koning JJ. van der Woude LH, et al. Med Eng Phys. 2008 Jun;30(5):574-80. doi: 10.1016/j.medengphy.2007.06.006. Epub 2007 Aug 20. Med Eng Phys. 2008. PMID: 17709272 Clinical Trial.
METHODS: n=9 able-bodied male subjects (age: 20.1+/-2.1 years) performed two (sub)maximal continuous hand cycle exercise tests, using the SYNC and ASYNC mode in a standardized commercial add-on hand cycle unit (counter-balanced order). Treadmill speed (1.89 and 2.17 m s(-1 …
METHODS: n=9 able-bodied male subjects (age: 20.1+/-2.1 years) performed two (sub)maximal continuous hand cycle exercise tests, using the SY …