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The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity.
Kamalian L, Douglas O, Jolly CE, Snoeys J, Simic D, Monshouwer M, Williams DP, Kevin Park B, Chadwick AE. Kamalian L, et al. Toxicol In Vitro. 2018 Dec;53:136-147. doi: 10.1016/j.tiv.2018.08.001. Epub 2018 Aug 7. Toxicol In Vitro. 2018. PMID: 30096366 Free article.
Furthermore, based upon comparing changes in respiratory parameters to those of the positive controls, rotenone and carbonyl cyanide m-chlorophenyl hydrazone, compounds were categorised into two mechanistic groups; inhibitors or uncouplers of the electron transport chain. …
Furthermore, based upon comparing changes in respiratory parameters to those of the positive controls, rotenone and carbonyl cyanide m …