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Page 1
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. Welsh JA, et al. J Extracell Vesicles. 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404. J Extracell Vesicles. 2024. PMID: 38326288 Free PMC article.
Cancer: A bioelectric disease?
Desoyer C, Šupe R, Ghorbanpour S, Goswami D, Khalaj M, Karami N, Brislinger D, Hauser CAE, Baumgartner C. Desoyer C, et al. Clin Transl Med. 2026 May;16(5):e70701. doi: 10.1002/ctm2.70701. Clin Transl Med. 2026. PMID: 42165099 Free PMC article. Review.
In diverse experimental systems, malignant cells consistently exhibit depolarised transmembrane potentials (V(m)), which correlate with proliferation, stemness, invasion and therapy resistance, suggesting depolarisation as a conserved bioelectric hallmark of malignancy. .. …
In diverse experimental systems, malignant cells consistently exhibit depolarised transmembrane potentials (V(m)), which correlate wi …
Rabies virus matrix protein targets host actin cytoskeleton: a protein-protein interaction analysis.
Zandi F, Khalaj V, Goshadrou F, Meyfour A, Gholami A, Enayati S, Mehranfar M, Rahmati S, Kheiri EV, Badie HG, Vaziri B. Zandi F, et al. Pathog Dis. 2021 Jan 6;79(1):ftaa075. doi: 10.1093/femspd/ftaa075. Pathog Dis. 2021. PMID: 33289839
Multifunctional matrix protein (M) of rabies virus (RABV) plays essential roles in the pathogenesis of rabies infection. ...Molecular docking simulations also demonstrated the formation of RABV M complexes. However, further confirmation with co-immunoprecipitation w …
Multifunctional matrix protein (M) of rabies virus (RABV) plays essential roles in the pathogenesis of rabies infection. ...Molecular …
A new multi-epitope vaccine candidate based on S and M proteins is effective in inducing humoral and cellular immune responses against SARS-CoV-2 variants: an in silico design approach.
Samimi Hashjin A, Sardari S, Rostamian M, Ahmadi K, Madanchi H, Khalaj V. Samimi Hashjin A, et al. J Biomol Struct Dyn. 2024;42(22):12505-12522. doi: 10.1080/07391102.2023.2270699. Epub 2023 Oct 24. J Biomol Struct Dyn. 2024. PMID: 37874075
Due to the emergence of new SARS-CoV-2 variants, other virus proteins with more conservancy, such as Membrane (M) protein, are desired for vaccine development. The reverse vaccinology approach was employed to design a multi-epitope SARS-CoV-2 vaccine candidate based on S a …
Due to the emergence of new SARS-CoV-2 variants, other virus proteins with more conservancy, such as Membrane (M) protein, are desire …
Imidazo[1,2-a]quinazolines as novel, potent EGFR-TK inhibitors: Design, synthesis, bioactivity evaluation, and in silico studies.
Hasanvand Z, Oghabi Bakhshaiesh T, Peytam F, Firoozpour L, Hosseinzadeh E, Motahari R, Moghimi S, Nazeri E, Toolabi M, Momeni F, Bijanzadeh H, Khalaj A, Baratte B, Josselin B, Robert T, Bach S, Esmaeili R, Foroumadi A. Hasanvand Z, et al. Bioorg Chem. 2023 Apr;133:106383. doi: 10.1016/j.bioorg.2023.106383. Epub 2023 Jan 20. Bioorg Chem. 2023. PMID: 36764231
These imidazoquinazolines (18a and 18o, in particular) had great anti-proliferative activities with IC(50) values in the micromolar ( M) range against PC3, HepG2, HeLa, and MDA-MB-231 comparing with Erlotinib as reference marketed drug. ...Afterwards, the kinase assay on t …
These imidazoquinazolines (18a and 18o, in particular) had great anti-proliferative activities with IC(50) values in the micromolar ( M …
Comparison of mid-term effectiveness and safety of one-anastomosis gastric bypass and sleeve gastrectomy in patients with super obesity (BMI 50 kg/m(2)).
Tasdighi E, Mousapour P, Khalaj A, Sadeghian Y, Mahdavi M, Valizadeh M, Barzin M. Tasdighi E, et al. Surg Today. 2022 May;52(5):854-862. doi: 10.1007/s00595-021-02387-2. Epub 2021 Oct 24. Surg Today. 2022. PMID: 34689285
PURPOSES: There is no consensus regarding the optimal bariatric procedure in patients with super obesity [body mass index (BMI) 50 kg/m(2)]. This study compared the outcomes of one-anastomosis gastric bypass (OAGB) with those of sleeve gastrectomy (SG) in these patients. …
PURPOSES: There is no consensus regarding the optimal bariatric procedure in patients with super obesity [body mass index (BMI) 50 kg/m …
Remission and relapse of diabetes after sleeve gastrectomy and one-anastomosis gastric bypass: The Tehran Obesity Treatment Study.
Sadeghi S, Hosseinpanah F, Khalaj A, Ebadinejad A, Mahdavi M, Valizadeh M, Barzin M. Sadeghi S, et al. Diabetes Obes Metab. 2024 Dec;26(12):6007-6015. doi: 10.1111/dom.15974. Epub 2024 Sep 30. Diabetes Obes Metab. 2024. PMID: 39344845
METHODS: An observational prospective study with 5 years of follow-up was conducted in a total of 891 patients (82.5% female) with concomitant T2DM and obesity (body mass index 30.0 kg/m(2)) undergoing SG or OAGB between March 2013 and March 2021. T2DM remission was defi …
METHODS: An observational prospective study with 5 years of follow-up was conducted in a total of 891 patients (82.5% female) with concomita …
Body Composition Changes Following Sleeve Gastrectomy Vs. One-Anastomosis Gastric Bypass: Tehran Obesity Treatment Study (TOTS).
Barzin M, Heidari Almasi M, Mahdavi M, Khalaj A, Valizadeh M, Hosseinpanah F. Barzin M, et al. Obes Surg. 2021 Dec;31(12):5286-5294. doi: 10.1007/s11695-021-05722-1. Epub 2021 Oct 12. Obes Surg. 2021. PMID: 34637105
MATERIALS AND METHODS: A prospective study was conducted on 3864 patients with severe obesity who underwent either SG (2746, 76.1% women, mean age: 39.2 11.6 years, and BMI: 44.3 5.6 kg/m(2)) or OAGB (1118, 82.2% women, age: 39.9 10.7 years, BMI: 45.6 6.3 kg/m …
MATERIALS AND METHODS: A prospective study was conducted on 3864 patients with severe obesity who underwent either SG (2746, 76.1% women, me …
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