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2003 1
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2020 1
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19 results
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Page 1
High-grade sarcoma diagnosis and prognosis: Biomarker discovery by mass spectrometry imaging.
Lou S, Balluff B, de Graaff MA, Cleven AH, Briaire-de Bruijn I, Bovée JV, McDonnell LA. Lou S, et al. Among authors: mcdonnell la. Proteomics. 2016 Jun;16(11-12):1802-13. doi: 10.1002/pmic.201500514. Proteomics. 2016. PMID: 27174013
Twenty diagnostic protein signals were found characteristic for specific tumors (p 0.05), amongst them acyl-CoA-binding protein (m/z 11 162), macrophage migration inhibitory factor (m/z 12 350), thioredoxin (m/z 11 608) and galectin-1 (m/z 14 633) were …
Twenty diagnostic protein signals were found characteristic for specific tumors (p 0.05), amongst them acyl-CoA-binding protein (m/z …
A deterministic model based on evidence for the associations between kinematic variables and sprint kayak performance.
McDonnell LK, Hume PA, Nolte V. McDonnell LK, et al. Sports Biomech. 2013 Sep;12(3):205-20. doi: 10.1080/14763141.2012.760106. Sports Biomech. 2013. PMID: 24245047 Review.

Our kinematic deterministic model for sprint kayaking performance shows that the average kayak velocity is determined by kayak stroke displacement and stroke time. Stroke time had the strongest correlation with 200-m race time (r = 0.86, p < 0.001), and stroke rate (inv

Our kinematic deterministic model for sprint kayaking performance shows that the average kayak velocity is determined by kayak stroke displa …
Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications.
Ràfols P, Vilalta D, Torres S, Calavia R, Heijs B, McDonnell LA, Brezmes J, Del Castillo E, Yanes O, Ramírez N, Correig X. Ràfols P, et al. Among authors: mcdonnell la. PLoS One. 2018 Dec 12;13(12):e0208908. doi: 10.1371/journal.pone.0208908. eCollection 2018. PLoS One. 2018. PMID: 30540827 Free PMC article.
The obtained spectra showed a high number of MS peaks in the low mass region (m/z below 1000 Da) with few background peaks, demonstrating the ability of the sputtered gold nanolayers of promoting the desorption/ionization of a wide range of metabolites. ...
The obtained spectra showed a high number of MS peaks in the low mass region (m/z below 1000 Da) with few background peaks, demonstra …
Lipid and protein maps defining arterial layers in atherosclerotic aorta.
Martin-Lorenzo M, Balluff B, Maroto AS, Carreira RJ, van Zeijl RJ, Gonzalez-Calero L, de la Cuesta F, Barderas MG, Lopez-Almodovar LF, Padial LR, McDonnell LA, Vivanco F, Alvarez-Llamas G. Martin-Lorenzo M, et al. Among authors: mcdonnell la. Data Brief. 2015 Jun 24;4:328-31. doi: 10.1016/j.dib.2015.06.005. eCollection 2015 Sep. Data Brief. 2015. PMID: 26217810 Free PMC article.
These data further complement main findings previously published in J Proteomics (M. Martin-Lorenzo et al., J. Proteomics. (In press); M. Martin-Lorenzo et al., J. ...
These data further complement main findings previously published in J Proteomics (M. Martin-Lorenzo et al., J. Proteomics. (In press) …
High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.
Ly A, Buck A, Balluff B, Sun N, Gorzolka K, Feuchtinger A, Janssen KP, Kuppen PJ, van de Velde CJ, Weirich G, Erlmeier F, Langer R, Aubele M, Zitzelsberger H, McDonnell L, Aichler M, Walch A. Ly A, et al. Among authors: mcdonnell l. Nat Protoc. 2016 Aug;11(8):1428-43. doi: 10.1038/nprot.2016.081. Epub 2016 Jul 14. Nat Protoc. 2016. PMID: 27414759
The method involves FFPE tissue sections that undergo deparaffinization and matrix coating by 9-aminoacridine before MALDI-MSI. Using this platform, we previously detected 1,500 m/z species in the mass range m/z 50-1,000 in FFPE samples; the overlap compared with fr …
The method involves FFPE tissue sections that undergo deparaffinization and matrix coating by 9-aminoacridine before MALDI-MSI. Using this p …
Prognostic Metabolite Biomarkers for Soft Tissue Sarcomas Discovered by Mass Spectrometry Imaging.
Lou S, Balluff B, Cleven AHG, Bovée JVMG, McDonnell LA. Lou S, et al. Among authors: mcdonnell la. J Am Soc Mass Spectrom. 2017 Feb;28(2):376-383. doi: 10.1007/s13361-016-1544-4. Epub 2016 Nov 21. J Am Soc Mass Spectrom. 2017. PMID: 27873216 Free PMC article.
Three metabolite signals were found to correlate with overall survival (m/z 180.9436 and 241.0118) and metastasis-free survival (m/z 160.8417). FTICR-MSI identified m/z 241.0118 as inositol cyclic phosphate and m/z 160.8417 as carnitine. ...
Three metabolite signals were found to correlate with overall survival (m/z 180.9436 and 241.0118) and metastasis-free survival (m
Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3×Tg Alzheimer mouse model.
Esteve C, Jones EA, Kell DB, Boutin H, McDonnell LA. Esteve C, et al. Among authors: mcdonnell la. Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):747-754. doi: 10.1016/j.bbapap.2017.04.002. Epub 2017 Apr 11. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28411106
In comparison with wild-type (WT) control mice MALDI-MSI revealed Alzheimer's disease-specific protein profiles, highlighting dramatic reductions of a protein with m/z 7560, which was assigned to neurogranin and validated by immunohistochemistry. ...
In comparison with wild-type (WT) control mice MALDI-MSI revealed Alzheimer's disease-specific protein profiles, highlighting dramatic reduc …
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