Age-dependent effects of metformin on human oligodendrocyte lineage cell ensheathment capacity.
Mohammadnia A, Cui QL, Weng C, Yaqubi M, Fernandes MGF, Hall JA, Dudley R, Srour M, Kennedy TE, Stratton JA, Antel JP.
Mohammadnia A, et al.
Brain Commun. 2024 Mar 28;6(2):fcae109. doi: 10.1093/braincomms/fcae109. eCollection 2024.
Brain Commun. 2024.
PMID: 38601917
Free PMC article.
A2B5+ progenitors and mature cells, derived from surgical tissues by immune-magnetic separation, were assessed for ensheathment capacity in nanofibre plates over 2 weeks. Metformin (10 M every other day) was added to selected cultures. RNA was extracted from treated and co …
A2B5+ progenitors and mature cells, derived from surgical tissues by immune-magnetic separation, were assessed for ensheathment capacity in …