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Butein combined with radiotherapy enhances radioresponse of gastric cancer cell by impairing DNA damage repair.
Habibi-Kelishomi Z, Goliaei B, Nikoofar A. Habibi-Kelishomi Z, et al. Biochem Biophys Res Commun. 2021 Sep 17;570:35-40. doi: 10.1016/j.bbrc.2021.07.022. Epub 2021 Jul 14. Biochem Biophys Res Commun. 2021. PMID: 34271434
Butein treatment abrogated the radiation-induced G2/M cell cycle arrest, increased DNA damage, enhanced apoptosis, and reduced colony-forming ability of irradiated cells. This study on MKN-45 cells demonstrates that combination of butein with radiotherapy increases its rad …
Butein treatment abrogated the radiation-induced G2/M cell cycle arrest, increased DNA damage, enhanced apoptosis, and reduced colony …
Prediction of chronic kidney disease in abdominal cancers radiation therapy using the functional assays of normal tissue complication probability models.
Haghbin A, Mostaar A, Paydar R, Bakhshandeh M, Nikoofar A, Houshyari M, Cheraghi S. Haghbin A, et al. J Cancer Res Ther. 2022 Apr-Jun;18(3):718-724. doi: 10.4103/jcrt.jcrt_179_21. J Cancer Res Ther. 2022. PMID: 35900545 Free article.
According to the common terminology criteria for the scoring system of adverse events, Grade 2 CKD (eGFR 30-59 ml/min/1.73 m(2)) was considered as the radiation therapy endpoint. Modeling and parameter estimation of NTCP models were performed for the Lyman-equivalent unifo …
According to the common terminology criteria for the scoring system of adverse events, Grade 2 CKD (eGFR 30-59 ml/min/1.73 m(2)) was …
Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study.
Khaleghi G, Mahdavi H, Mahdavi SR, Khajetash B, Nikoofar A, Hosntalab M, Sadeghi M, Reiazi R. Khaleghi G, et al. Int J Implant Dent. 2021 Sep 6;7(1):90. doi: 10.1186/s40729-021-00372-5. Int J Implant Dent. 2021. PMID: 34486092 Free PMC article.
RESULTS: At the level of crowns, upstream and downstream dose calculations were reduced when metal kernels were applied (M-plan). Moreover, relatively measured dose distribution patterns were most similar to M-plan. ...
RESULTS: At the level of crowns, upstream and downstream dose calculations were reduced when metal kernels were applied (M-plan). Mor …
Comparison of the Pathological Response and Adverse Effects of Oxaliplatin and Capecitabine versus Paclitaxel and Carboplatin in the Neoadjuvant Chemoradiotherapy Treatment Approach for Esophageal and Gastroesophageal Junction Cancer: A Randomized Control Trial Study.
Cheraghi A, Barahman M, Hariri R, Nikoofar A, Fadavi P. Cheraghi A, et al. Med J Islam Repub Iran. 2021 Oct 25;35:140. doi: 10.47176/mjiri.35.140. eCollection 2021. Med J Islam Repub Iran. 2021. PMID: 35321371 Free PMC article.
The first group received capecitabine (625 mg/m(2)/TID) and oxaliplatin (50 mg/m(2)/weekly), while the second group was given a combination of carboplatin (AUC:2/weekly) and paclitaxel (75mg/m(2)/weekly). ...
The first group received capecitabine (625 mg/m(2)/TID) and oxaliplatin (50 mg/m(2)/weekly), while the second group was given …
Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis.
Bigdeli B, Goliaei B, Masoudi-Khoram N, Jooyan N, Nikoofar A, Rouhani M, Haghparast A, Mamashli F. Bigdeli B, et al. Toxicol Appl Pharmacol. 2016 Dec 15;313:180-194. doi: 10.1016/j.taap.2016.10.021. Epub 2016 Oct 28. Toxicol Appl Pharmacol. 2016. PMID: 27984132
Enterolactone significantly enhanced radiosensitivity of cells by abrogating G2/M arrest, impairing DNA repair, and increasing radiation-induced apoptosis. Furthermore, increased chromosomal damages and aberrations were detected in cells treated with enterolactone combined …
Enterolactone significantly enhanced radiosensitivity of cells by abrogating G2/M arrest, impairing DNA repair, and increasing radiat …
Reducing the effective dosage of Mitomycin C on a high-grade bladder cancer cell line through combination with selenium nanoparticles: An in vitro study.
Oskouie IM, Amirzargar H, Dezfuli AS, Mashhadi R, Mirzaei A, Shamshirgaran A, Nikoofar P, Aghamir SMK. Oskouie IM, et al. Med Oncol. 2025 May 10;42(6):207. doi: 10.1007/s12032-025-02758-6. Med Oncol. 2025. PMID: 40348879

The co-administration of SeNPs and MMC (178.8 M SeNPs + 14.9 M MMC) significantly increased the rate of early apoptosis in the T24 cell line compared to MMC alone (29.8 M, p < 0.0001). Additionally, SeNPs and MMC induced cell cycle arrest at the SubG1/G1 a

…
The co-administration of SeNPs and MMC (178.8 M SeNPs + 14.9 M MMC) significantly increased the rate of early apoptosis in the …
Caffeic Acid Phenethyl Ester Increases Radiosensitivity of Estrogen Receptor-Positive and -Negative Breast Cancer Cells by Prolonging Radiation-Induced DNA Damage.
Khoram NM, Bigdeli B, Nikoofar A, Goliaei B. Khoram NM, et al. J Breast Cancer. 2016 Mar;19(1):18-25. doi: 10.4048/jbc.2016.19.1.18. Epub 2016 Mar 25. J Breast Cancer. 2016. PMID: 27066092 Free PMC article.
To assess clonogenic ability, MDA-MB-231 and T47D cells were treated with CAPE (1 M) for 72 hours before irradiation, and then, a colony assay was performed. A comet assay was used to determine the number of DNA strand breaks at four different times. ...
To assess clonogenic ability, MDA-MB-231 and T47D cells were treated with CAPE (1 M) for 72 hours before irradiation, and then, a col …