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Did you mean M. pajoohesh (11 results)?
Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection.
Shoemaker CJ, Schornberg KL, Delos SE, Scully C, Pajouhesh H, Olinger GG, Johansen LM, White JM. Shoemaker CJ, et al. PLoS One. 2013;8(2):e56265. doi: 10.1371/journal.pone.0056265. Epub 2013 Feb 18. PLoS One. 2013. PMID: 23441171 Free PMC article.
From this screen we identified six compounds, including U18666A, that block EBOV infection (IC(50) 1.6 to 8.0 M) at a late stage of entry. Intriguingly, all six are cationic amphiphiles that share additional chemical features. ...
From this screen we identified six compounds, including U18666A, that block EBOV infection (IC(50) 1.6 to 8.0 M) at a late stage of e …
A fluorescence-based high-throughput screening assay for the identification of T-type calcium channel blockers.
Belardetti F, Tringham E, Eduljee C, Jiang X, Dong H, Hendricson A, Shimizu Y, Janke DL, Parker D, Mezeyova J, Khawaja A, Pajouhesh H, Fraser RA, Arneric SP, Snutch TP. Belardetti F, et al. Assay Drug Dev Technol. 2009 Jun;7(3):266-80. doi: 10.1089/adt.2009.191. Assay Drug Dev Technol. 2009. PMID: 19530894
One notable challenge is that at the normal resting membrane potential (V(m)) of cell lines commonly utilized for drug screening purposes, T-type Ca(2+) channels are largely inactivated and thus cannot be supported by typical formats of functional HTS assays to both evoke …
One notable challenge is that at the normal resting membrane potential (V(m)) of cell lines commonly utilized for drug screening purp …
Phase transition properties of aqueous dispersions of homologues of all-trans 2,3-dipalmitoylcyclopentano-1-phosphocholine.
Jain MK, Singer MA, Crecely RW, Pajouhesh H, Hancock AJ. Jain MK, et al. Biochim Biophys Acta. 1984 Jul 25;774(2):199-205. doi: 10.1016/0005-2736(84)90292-x. Biochim Biophys Acta. 1984. PMID: 6743654
In a previous publication, (Singer, M.A., Jain, M.K., Sable, H.Z., Pownall, H.H., Mantulin, W.W., Lister, M.D. and Hancock, A.J. (1983) Biochim. ...
In a previous publication, (Singer, M.A., Jain, M.K., Sable, H.Z., Pownall, H.H., Mantulin, W.W., Lister, M.D. and Hanc …