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24 results

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Page 1
Global, regional, and national mortality among young people aged 10-24 years, 1950-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Adolescent Mortality Collaborators. GBD 2019 Adolescent Mortality Collaborators. Lancet. 2021 Oct 30;398(10311):1593-1618. doi: 10.1016/S0140-6736(21)01546-4. Epub 2021 Oct 28. Lancet. 2021. PMID: 34755628 Free PMC article.
INTERPRETATION: Variation in adolescent mortality between countries and by sex is widening, driven by poor progress in reducing deaths in males and older adolescents. Improving global adolescent mortality will require action to address the specific vulnerabilities of this …
INTERPRETATION: Variation in adolescent mortality between countries and by sex is widening, driven by poor progress in reducing death …
Immunotherapy in Non-Small Cell Lung Cancer Patients with Brain Metastases: Clinical Challenges and Future Directions.
Pathak R, Amini A, Hill A, Massarelli E, Salgia R. Pathak R, et al. Cancers (Basel). 2021 Jul 7;13(14):3407. doi: 10.3390/cancers13143407. Cancers (Basel). 2021. PMID: 34298620 Free PMC article. Review.
Existing treatment paradigms for brain metastases in lung cancer patients leave patients with adverse neurocognitive function, poor quality of life, and dismal prognosis, thus highlighting the need to develop more effective systemic therapies. ...
Existing treatment paradigms for brain metastases in lung cancer patients leave patients with adverse neurocognitive function, poor q …
Can sarcopenia predict poor prognosis of sepsis due to acute cholecystitis?
Kim HB, Chun SY, Kim GW, Lim H, Cho YS. Kim HB, et al. Am J Emerg Med. 2023 Nov;73:69-74. doi: 10.1016/j.ajem.2023.08.014. Epub 2023 Aug 10. Am J Emerg Med. 2023. PMID: 37619445

Sarcopenia was defined as PMI < 423 mm(2)/m(2) for males and < 269 mm(2)/m(2) for females. There were 94 patients in the sarcopenic group and 280 in the non-sarcopenic group. ...Additionally, the median LOS in the sarcopenic group (11.5 (Cruz-Jentoft et al., 2

Sarcopenia was defined as PMI < 423 mm(2)/m(2) for males and < 269 mm(2)/m(2) for females. There were 94 patients in the

Soluble CD163 predicts outcome in both chemoimmunotherapy and targeted therapy-treated mantle cell lymphoma.
Nikkarinen A, Lokhande L, Amini RM, Jerkeman M, Porwit A, Molin D, Enblad G, Kolstad A, Räty R, Hutchings M, Weibull CE, Hollander P, Ek S, Glimelius I. Nikkarinen A, et al. Blood Adv. 2023 Sep 26;7(18):5304-5313. doi: 10.1182/bloodadvances.2023010052. Blood Adv. 2023. PMID: 37389827 Free PMC article.
There was a moderate correlation between sCD163 and tissue CD163. The association with a poor prognosis was independent of MCL international prognostic index, Ki67, p53 status, and blastoid morphology, as assessed in a multivariable Cox proportional hazards model. ...
There was a moderate correlation between sCD163 and tissue CD163. The association with a poor prognosis was independent of MCL intern …
Investigating the effect of LncRNA DLGAP1-AS2 suppression on chemosensitivity of gastric cancer to chemotherapy.
Azadi SS, Safaralizadeh R, Amini M, Hosseinpour Feizi MA, Abdolzadeh S, Najafi S, Bahojb Mahdavi SZ, Yari A, Narimanzadeh L, Baradaran B, Mokhtarzadeh AA. Azadi SS, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct;397(10):7891-7903. doi: 10.1007/s00210-024-03130-7. Epub 2024 May 15. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38748228
Gastric cancer, as the fifth most frequent disease and the fourth foremost cause of cancer-related death worldwide, remains a main clinical challenge due to its poor prognosis, limited treatment choices, and ability to metastasize. Combining siRNAs to suppress lncRNA with …
Gastric cancer, as the fifth most frequent disease and the fourth foremost cause of cancer-related death worldwide, remains a main clinical …
Strategic self-limiting production of infectious HIV particles by CRISPR in permissive cells.
Liu H, Chen C, Liao S, Sohaii DK, Cruz CRY, Burdo TH, Cradick TJ, Mehta A, Barrero C, Florez M, Gordon J, Grauzam S, Dressman J, Amini S, Bollard CM, Kaminski R, Khalili K. Liu H, et al. Mol Ther Nucleic Acids. 2023 May 19;32:1010-1025. doi: 10.1016/j.omtn.2023.04.027. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37346975 Free PMC article.
Controlled activation of CRISPR-MOGS by rebound HIV-1 mitigates production of infectious particles that exhibit poor ability of the virus to penetrate uninfected cells. Moreover, exclusive activation of CRISPR in cells infected with HIV-1 alleviates concern for broad off-t …
Controlled activation of CRISPR-MOGS by rebound HIV-1 mitigates production of infectious particles that exhibit poor ability of the v …
Inhibition of HIV-1 infection with curcumin conjugated PEG-citrate dendrimer; a new nano formulation.
Ebrahimi S, Sadeghizadeh M, Aghasadeghi MR, Ardestani MS, Amini SA, Vahabpour R. Ebrahimi S, et al. BMC Complement Med Ther. 2024 Oct 2;24(1):350. doi: 10.1186/s12906-024-04634-8. BMC Complement Med Ther. 2024. PMID: 39358802 Free PMC article.
However, its optimum potential has been significantly hampered due to its poor water solubility, which leads to reduced bioavailability. So, the present study attempted to address this issue and investigate its antiviral effects against HIV-1. ...Inhibition of HIV-1 at con …
However, its optimum potential has been significantly hampered due to its poor water solubility, which leads to reduced bioavailabili …
Modified Spatially Confined Strategy Enabled Mild Growth Kinetics for Facile Growth Management of Atomically-Thin Tungsten Disulfides.
Wang Q, Wang S, Li J, Gan Y, Jin M, Shi R, Amini A, Wang N, Cheng C. Wang Q, et al. Adv Sci (Weinh). 2023 Jan;10(3):e2205638. doi: 10.1002/advs.202205638. Epub 2022 Nov 29. Adv Sci (Weinh). 2023. PMID: 36446619 Free PMC article.
However, violent evaporation and large diffusivity discrepancy of metal and chalcogen precursors at elevated temperatures often result in poor regulation on X:M molar ratio (M = Mo, W etc.; X = S, Se, and Te), and thus it is rather challenging to achieve the …
However, violent evaporation and large diffusivity discrepancy of metal and chalcogen precursors at elevated temperatures often result in …
Revisiting IL-6 expression in the tumor microenvironment of classical Hodgkin lymphoma.
Gholiha AR, Hollander P, Glimelius I, Hedstrom G, Molin D, Hjalgrim H, Smedby KE, Hashemi J, Amini RM, Enblad G. Gholiha AR, et al. Blood Adv. 2021 Mar 23;5(6):1671-1681. doi: 10.1182/bloodadvances.2020003664. Blood Adv. 2021. PMID: 33720338 Free PMC article.
The adverse survival was maintained in multivariate Cox regression and propensity score-matched analyses, adjusting for well-known poor-prognostic covariates. The presence of IL-6+ HRS cells and high serum IL-6 levels were not associated with survival. ...
The adverse survival was maintained in multivariate Cox regression and propensity score-matched analyses, adjusting for well-known poor
24 results