Identification of highly effective antitrypanosomal compounds in essential oils from the Apiaceae family.
Ngahang Kamte SL, Ranjbarian F, Cianfaglione K, Sut S, Dall'Acqua S, Bruno M, Afshar FH, Iannarelli R, Benelli G, Cappellacci L, Hofer A, Maggi F, Petrelli R.
Ngahang Kamte SL, et al.
Ecotoxicol Environ Saf. 2018 Jul 30;156:154-165. doi: 10.1016/j.ecoenv.2018.03.032. Epub 2018 Mar 20.
Ecotoxicol Environ Saf. 2018.
PMID: 29549739
Terpinolene was particularly active with an EC(50) value of 0.035 mug/mL (0.26 M) and a selectivity index (SI) of 180. Four other compounds with EC(50) in the range 1.0-6.0 mug/mL (7.4-44 M) had also good SI: alpha-pinene (>100), beta-ocimene (>91), limonene …
Terpinolene was particularly active with an EC(50) value of 0.035 mug/mL (0.26 M) and a selectivity index (SI) of 180. Four other co …