Genetic basis of early onset and progression of type 2 diabetes in South Asians.
Hodgson S, Williamson A, Bigossi M, Stow D, Jacobs BM, Samuel M, Gafton J, Zöllner J, Spreckley M; Genes & Health Research Team; Langenberg C, van Heel DA, Mathur R, Siddiqui MK, Finer S.
Hodgson S, et al.
Nat Med. 2025 Jan;31(1):323-331. doi: 10.1038/s41591-024-03317-8. Epub 2024 Nov 26.
Nat Med. 2025.
PMID: 39592779
Free PMC article.
Individuals at high genetic risk of both insulin deficiency and lipodystrophy were diagnosed with T2D 8.2 years earlier with BMI 3 kg m(-)(2) lower compared to those at low genetic risk. The insulin deficiency pPS was associated with poorer HbA1c response to SGLT2 inhibito …
Individuals at high genetic risk of both insulin deficiency and lipodystrophy were diagnosed with T2D 8.2 years earlier with BMI 3 kg m …