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Page 1
CaV3.1 channels facilitate calcium wave generation and myogenic tone development in mouse mesenteric arteries.
El-Lakany MA, Haghbin N, Arora N, Hashad AM, Mironova GY, Sancho M, Gros R, Welsh DG. El-Lakany MA, et al. Sci Rep. 2023 Nov 21;13(1):20407. doi: 10.1038/s41598-023-47715-3. Sci Rep. 2023. PMID: 37989780 Free PMC article.
This reduction coincided with diminished Ca(2+) wave generation, asynchronous events of Ca(2+) release from the sarcoplasmic reticulum, insensitive to L-type Ca(2+) channel blockade (Nifedipine, 0.3 M). Proximity ligation assay (PLA) confirmed IP(3)R1/Ca(V)3.1 close physic …
This reduction coincided with diminished Ca(2+) wave generation, asynchronous events of Ca(2+) release from the sarcoplasmic reticulum, inse …
Functional bias of contractile control in mouse resistance arteries.
Haghbin N, Richter DM, Kharche S, Kim MSM, Welsh DG. Haghbin N, et al. Sci Rep. 2024 Oct 22;14(1):24940. doi: 10.1038/s41598-024-75838-8. Sci Rep. 2024. PMID: 39438518 Free PMC article.
Constrictor agonists set arterial tone through two coupling processes, one tied to (electromechanical), the other independent (pharmacomechanical) of, membrane potential (V(M)). This dual arrangement raises an intriguing question: is the contribution of each mechanism (1) …
Constrictor agonists set arterial tone through two coupling processes, one tied to (electromechanical), the other independent (pharmacomecha …
Prediction of chronic kidney disease in abdominal cancers radiation therapy using the functional assays of normal tissue complication probability models.
Haghbin A, Mostaar A, Paydar R, Bakhshandeh M, Nikoofar A, Houshyari M, Cheraghi S. Haghbin A, et al. J Cancer Res Ther. 2022 Apr-Jun;18(3):718-724. doi: 10.4103/jcrt.jcrt_179_21. J Cancer Res Ther. 2022. PMID: 35900545 Free article.
According to the common terminology criteria for the scoring system of adverse events, Grade 2 CKD (eGFR 30-59 ml/min/1.73 m(2)) was considered as the radiation therapy endpoint. Modeling and parameter estimation of NTCP models were performed for the Lyman-equivalent unifo …
According to the common terminology criteria for the scoring system of adverse events, Grade 2 CKD (eGFR 30-59 ml/min/1.73 m(2)) was …