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Page 1
Showing results for M.K. pair
Your search for M.K. Pazir retrieved no results
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
One strategy to suppress nonsense mutations is to use natural tRNAs with altered anticodons to base-pair to the newly emerged PTC and promote translation(2-7). However, tRNA-based gene therapy has not yielded an optimal combination of clinical efficacy and safety and there …
One strategy to suppress nonsense mutations is to use natural tRNAs with altered anticodons to base-pair to the newly emerged PTC and …
Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy.
Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F, Al-Atrash G, Takahashi K, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S, Konopleva M, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A, Garcia-Manero G, Green MR, Sharma P, Allison JP, Kornblau SM, Rai K, Wang L, Daver N, Futreal A. Abbas HA, et al. Nat Commun. 2021 Oct 18;12(1):6071. doi: 10.1038/s41467-021-26282-z. Nat Commun. 2021. PMID: 34663807 Free PMC article.
Genomic mechanisms of resistance to venetoclax in multiple myeloma with t(11;14)(CCND1;IGH).
Kaddoura M, Wiedmeier-Nutor JE, Gupta VA, Jelinek T, Ziccheddu B, Shivaram S, Tang H, Owens RW, Sevcikova T, Fonseca R, Durante M, Diamond B, Zhao L, Zhu YX, Shi CX, Matulis SM, Mitsiades CS, Landgren O, Usmani S, Hajek R, Chesi M, Bergsagel PL, Braggio E, Boise LH, Fonseca R, Kumar S, Maura F, Baughn LB. Kaddoura M, et al. Blood. 2026 Apr 2;147(14):1598-1610. doi: 10.1182/blood.2025029996. Blood. 2026. PMID: 41481388 Free PMC article.
Longitudinal molecular trajectories of diffuse glioma in adults.
Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW; GLASS Consortium. Barthel FP, et al. Nature. 2019 Dec;576(7785):112-120. doi: 10.1038/s41586-019-1775-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31748746 Free PMC article.
Safety and outcomes of intravenous thrombolysis in acute ischemic stroke with intracranial artery dissection.
Egashira S, Kunisawa S, Koga M, Ihara M, Tsuruta W, Uesaka Y, Fushimi K, Toda T, Imanaka Y. Egashira S, et al. Int J Stroke. 2025 Jul;20(6):741-749. doi: 10.1177/17474930251317326. Epub 2025 Feb 20. Int J Stroke. 2025. PMID: 39834052
AIMS: This study aimed to assess whether IAD is associated with an increased risk of intracranial hemorrhage (ICH) following IVT and to evaluate its impact on functional outcomes. METHODS: This retrospective matched-pair cohort study used a nationwide inpatient database th …
AIMS: This study aimed to assess whether IAD is associated with an increased risk of intracranial hemorrhage (ICH) following IVT and to eval …
Comparison of K-Sol and M-K medium for cornea storage: results of penetrating keratoplasty in rabbits.
Busin M, Yau CW, Avni I, Kaufman HE. Busin M, et al. Br J Ophthalmol. 1986 Nov;70(11):860-3. doi: 10.1136/bjo.70.11.860. Br J Ophthalmol. 1986. PMID: 3098277 Free PMC article.
Five pairs of rabbit corneas were stored for two weeks at 4 degrees C, one of each pair in K-Sol medium, and one in McCarey-/Kaufman (M-K) medium. After transplantation all penetrating keratoplasty grafts became clear and thin. ...The results indicate that K- …
Five pairs of rabbit corneas were stored for two weeks at 4 degrees C, one of each pair in K-Sol medium, and one in McCarey-/Kaufman …
Large static first and second hyperpolarizabilities dominated by excess electron transition for radical ion pair salts M2*+TCNQ*- (M=Li, Na, K).
Li ZJ, Wang FF, Li ZR, Xu HL, Huang XR, Wu D, Chen W, Yu GT, Gu FL, Aoki Y. Li ZJ, et al. Phys Chem Chem Phys. 2009 Jan 14;11(2):402-8. doi: 10.1039/b809161g. Epub 2008 Nov 4. Phys Chem Chem Phys. 2009. PMID: 19088997

The interesting radical ion pair salts M(2)*(+)TCNQ*(-) (M=Li, Na, K) are a particular class of charge transfer complexes with excess electron. ...The order of beta(0) values is 19 203 (M=Li)<24 140 (M=Na) < 29 065 a.u. (M=K). Specially, the second hype

…
The interesting radical ion pair salts M(2)*(+)TCNQ*(-) (M=Li, Na, K) are a particular class of charge transfer complexes with excess …
Lead-it-EAZY! GMP-compliant production of [212Pb]Pb-PSC-PEG2-TOC.
Pretze M, Michler E, Kästner D, Kunkel F, Sagastume EA, Schultz MK, Kotzerke J. Pretze M, et al. EJNMMI Radiopharm Chem. 2024 Nov 27;9(1):81. doi: 10.1186/s41181-024-00305-8. EJNMMI Radiopharm Chem. 2024. PMID: 39604560 Free PMC article.
BACKGROUND: Recently, radiotheranostics comprising the true matched radionuclide pair (203/212)Pb could serve as real dosimetric planning utility using (203)Pb-radiolabelled pharmaceuticals before therapy with (212)Pb-radiolabelled counterparts. (212)Pb might act as the mi …
BACKGROUND: Recently, radiotheranostics comprising the true matched radionuclide pair (203/212)Pb could serve as real dosimetric plan …
Nardilysin cleaves peptides at monobasic sites.
Chow KM, Oakley O, Goodman J, Ma Z, Juliano MA, Juliano L, Hersh LB. Chow KM, et al. Biochemistry. 2003 Feb 25;42(7):2239-44. doi: 10.1021/bi027178d. Biochemistry. 2003. PMID: 12590613
Nardilysin cleaves beta-endorphin at the monobasic site, Phe(17)-Lys(18), with a k(cat)/K(m) of 2 x 10(8) M(-)(1) min(-)(1). This can be compared to a k(cat)/K(m) of 8.5 x 10(8) M(-)(1) min(-)(1) for cleavage between a dibasic pair in dynorphin …
Nardilysin cleaves beta-endorphin at the monobasic site, Phe(17)-Lys(18), with a k(cat)/K(m) of 2 x 10(8) M(-)(1) min(-)(1). T …
Effects of Tcte1 knockout on energy chain transportation and spermatogenesis: implications for male infertility.
Olszewska M, Malcher A, Stokowy T, Pollock N, Berman AJ, Budkiewicz S, Kamieniczna M, Jackowiak H, Suszynska-Zajczyk J, Jedrzejczak P, Yatsenko AN, Kurpisz M. Olszewska M, et al. Hum Reprod Open. 2024 Apr 4;2024(2):hoae020. doi: 10.1093/hropen/hoae020. eCollection 2024. Hum Reprod Open. 2024. PMID: 38650655 Free PMC article.
PARTICIPANTS/MATERIALS SETTING METHODS: To check the reproductive potential of KO mice, adult animals were crossed for delivery of three litters per caged pair, but for no longer than for 6 months, in various combinations of zygosity. All experiments were performed for wil …
PARTICIPANTS/MATERIALS SETTING METHODS: To check the reproductive potential of KO mice, adult animals were crossed for delivery of three lit …
127 results