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Page 1
8-Oxo-9-Dihydromakomakine Isolated from Aristotelia chilensis Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx.
Cifuentes F, Palacios J, Paredes A, Nwokocha CR, Paz C. Cifuentes F, et al. Molecules. 2018 Nov 21;23(11):3050. doi: 10.3390/molecules23113050. Molecules. 2018. PMID: 30469451 Free PMC article.

The addition of 8-oxo-9-dihydromakomakine (10(-5) M) decreased the contractile response to tetraethylammonium (a voltage-dependent potassium channels blocker; TEA; 5 10(-3) M; p < 0.01) and BaCl2 (a non-selective inward rectifier potassium channel blocker; 5 10(-

…
The addition of 8-oxo-9-dihydromakomakine (10(-5) M) decreased the contractile response to tetraethylammonium (a voltage-dependent potassium …
CAPPRIC Study-Characterization of Community-Acquired Pneumonia in Spanish Adults Managed in Primary Care Settings.
Molina J, González-Gamarra A, Ginel L, Peláez ME, Juez JL, Artuñedo A, Aldana G, Quesada E, Cabré JJ, Gómez A, Linares M, Marín MT, Yolanda Sanchez P, Núñez L, Gonzálvez J, Mascarós E, López J, Cano A, Herrero J, Carmen Serra M, Cimas E, Pedrol M, Alfaro JV, Martinón-Torres F, Cifuentes I, Méndez C, Ocaña D, On Behalf Of The Cappric Study Group. Molina J, et al. Microorganisms. 2021 Feb 28;9(3):508. doi: 10.3390/microorganisms9030508. Microorganisms. 2021. PMID: 33670930 Free PMC article.
Prevalence and factors associated with liver steatosis as measured by transient elastography with controlled attenuation parameter in HIV-infected patients.
Macías J, González J, Tural C, Ortega-González E, Pulido F, Rubio R, Cifuentes C, Díaz-Menéndez M, Jou A, Rubio P, Burgos A, Pineda JA. Macías J, et al. AIDS. 2014 Jun 1;28(9):1279-87. doi: 10.1097/QAD.0000000000000248. AIDS. 2014. PMID: 24614088

Patients with SHS compared with those without SHS presented higher median (IQR) BMI [BMI, 25.6 (22.5-28) vs. 22.3 (20.3-24.2) kg/m; P < 10], DBP [79 (72-85) vs. 74 (68-81) mmHg; P = 0.0001], fasting plasma glucose [95 (87-106) vs. 91 (84-97) mg/dl; P = 0.002] and

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Patients with SHS compared with those without SHS presented higher median (IQR) BMI [BMI, 25.6 (22.5-28) vs. 22.3 (20.3-24.2) kg/m; …
Metabolomic Profiling of Mango (Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models.
Ybañez-Julca RO, Asunción-Alvarez D, Quispe-Díaz IM, Palacios J, Bórquez J, Simirgiotis MJ, Perveen S, Nwokocha CR, Cifuentes F, Paredes A. Ybañez-Julca RO, et al. Molecules. 2020 Nov 5;25(21):5149. doi: 10.3390/molecules25215149. Molecules. 2020. PMID: 33167456 Free PMC article.
Similar effects were observed with mangiferin and quercetin (10(-5) M; p < 0.05) but not for gallic acid. Chronic treatment of rats with MIE (50 mg/kg) for 28 days significantly reduced (p < 0.001) the H(2)O(2)-induced contractions. ...

Similar effects were observed with mangiferin and quercetin (10(-5) M; p < 0.05) but not for gallic acid. Chronic treatment

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Na+ -K+ -2Cl- cotransporter is implicated in gender differences in the response of the rat aorta to phenylephrine.
Palacios J, Espinoza F, Munita C, Cifuentes F, Michea L. Palacios J, et al. Br J Pharmacol. 2006 Aug;148(7):964-72. doi: 10.1038/sj.bjp.0706818. Epub 2006 Jun 26. Br J Pharmacol. 2006. PMID: 16799647 Free PMC article.
Inhibition of the Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) with bumetanide reduced contractile responses to phenylephrine (PE) in male rat aortas (129+/-4% of 60 mM KCl-induced contraction control vs 108+/-7% bumetanide; PE 10(-5) M; P<0.01) but did not change equ …
Inhibition of the Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) with bumetanide reduced contractile responses to phenylephrine (PE) in male rat ao …