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Year Number of Results
1852 1
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1950 1
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1953 4
1954 1
1955 1
1956 3
1957 1
1959 1
1960 1
1961 2
1962 1
1963 5
1964 1
1966 13
1967 5
1968 7
1969 7
1970 22
1971 29
1972 22
1973 19
1974 35
1975 200
1976 308
1977 279
1978 347
1979 423
1980 519
1981 606
1982 754
1983 909
1984 1047
1985 1201
1986 1346
1987 1497
1988 1517
1989 2011
1990 2112
1991 2255
1992 2345
1993 2512
1994 2722
1995 2920
1996 3092
1997 3230
1998 3345
1999 3370
2000 3152
2001 3045
2002 2927
2003 3216
2004 3549
2005 4470
2006 4666
2007 4401
2008 4214
2009 4029
2010 4646
2011 5238
2012 5698
2013 6509
2014 6826
2015 6931
2016 6570
2017 7086
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2024 12970
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209,318 results

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The following term was not found in PubMed: Tghiloo
Page 1
Microglia Polarization From M1 to M2 in Neurodegenerative Diseases.
Guo S, Wang H, Yin Y. Guo S, et al. Front Aging Neurosci. 2022 Feb 16;14:815347. doi: 10.3389/fnagi.2022.815347. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35250543 Free PMC article. Review.
Microglia can be categorized into two opposite types: classical (M1) or alternative (M2), though there's a continuum of different intermediate phenotypes between M1 and M2, and microglia can transit from one phenotype to another. ...Previous studies showed that bala …
Microglia can be categorized into two opposite types: classical (M1) or alternative (M2), though there's a continuum of different int …
Melatonin Engineering M2 Macrophage-Derived Exosomes Mediate Endoplasmic Reticulum Stress and Immune Reprogramming for Periodontitis Therapy.
Cui Y, Hong S, Xia Y, Li X, He X, Hu X, Li Y, Wang X, Lin K, Mao L. Cui Y, et al. Adv Sci (Weinh). 2023 Sep;10(27):e2302029. doi: 10.1002/advs.202302029. Epub 2023 Jul 14. Adv Sci (Weinh). 2023. PMID: 37452425 Free PMC article.
An appropriate and timely transition from proinflammatory (M1) to anti-inflammatory (M2) macrophages is indispensable for treating periodontitis. As M2 macrophage-derived exosomes (M2-exos) can actively target inflammatory sites and modulate immune microenvir …
An appropriate and timely transition from proinflammatory (M1) to anti-inflammatory (M2) macrophages is indispensable for treating pe …
Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms.
Rőszer T. Rőszer T. Mediators Inflamm. 2015;2015:816460. doi: 10.1155/2015/816460. Epub 2015 May 18. Mediators Inflamm. 2015. PMID: 26089604 Free PMC article. Review.
Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. ...Also, it provides an update on the novel signals of the tissue environment and the neuroendocrine system which shape the M2 activation. The possible evolutionar …
Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. ...Also, it provides an update …
Macrophage M1/M2 polarization and rheumatoid arthritis: A systematic review.
Tardito S, Martinelli G, Soldano S, Paolino S, Pacini G, Patane M, Alessandri E, Smith V, Cutolo M. Tardito S, et al. Autoimmun Rev. 2019 Nov;18(11):102397. doi: 10.1016/j.autrev.2019.102397. Epub 2019 Sep 11. Autoimmun Rev. 2019. PMID: 31520798
Analyses of the endogenous molecules and the drugs that could modulate M1 and M2 activity in RA were achieved. METHODS: A sensitive search was developed in Pubmed, Web of Science, Ovid Med-Line, Embase Database and Science Direct Database (la both from Elsevier) to identif …
Analyses of the endogenous molecules and the drugs that could modulate M1 and M2 activity in RA were achieved. METHODS: A sensitive s …
M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulator.
Wang Y, Lin Q, Zhang H, Wang S, Cui J, Hu Y, Liu J, Li M, Zhang K, Zhou F, Jing Y, Geng Z, Su J. Wang Y, et al. Bioact Mater. 2023 Jun 1;28:273-283. doi: 10.1016/j.bioactmat.2023.05.018. eCollection 2023 Oct. Bioact Mater. 2023. PMID: 37303851 Free PMC article.
We further confirmed that M2-exosomes induced the conversion of M1 macrophages into M2 macrophages by stimulating the PI3K/AKT pathway. Our study offers a fresh perspective and a potential therapeutic approach for M2-exosomes to improve diabetic fracture heal …
We further confirmed that M2-exosomes induced the conversion of M1 macrophages into M2 macrophages by stimulating the PI3K/AKT …
Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA.
Chen X, Wan Z, Yang L, Song S, Fu Z, Tang K, Chen L, Song Y. Chen X, et al. J Nanobiotechnology. 2022 Mar 5;20(1):110. doi: 10.1186/s12951-022-01314-y. J Nanobiotechnology. 2022. PMID: 35248085 Free PMC article.
Among them, reparative M2-like macrophages have been shown to promote tissue repair and prevent bone loss. However, the mechanism of reparative M2 macrophages-induced osteoprotective effect remains elusive. ...High expression level of IL-10 mRNA was detected not onl …
Among them, reparative M2-like macrophages have been shown to promote tissue repair and prevent bone loss. However, the mechanism of …
Branched-chain amino acid catabolism promotes M2 macrophage polarization.
Lu M, Luo D, Zhang Z, Ouyang F, Shi Y, Hu C, Su H, Li Y, Zhang J, Gui Q, Yang TS. Lu M, et al. Front Immunol. 2024 Nov 8;15:1469163. doi: 10.3389/fimmu.2024.1469163. eCollection 2024. Front Immunol. 2024. PMID: 39582859 Free PMC article.
METHOD: The metabolomics of BMDM-derived M0 and M2 macrophages were analyzed using LC-MS. BCAAs were supplemented and genes involved in BCAA catabolism were inhibited during M2 macrophage polarization. The expression of M2 marker genes was assessed through RT …
METHOD: The metabolomics of BMDM-derived M0 and M2 macrophages were analyzed using LC-MS. BCAAs were supplemented and genes involved …
M2 macrophage exosome-derived Apoc1 promotes ferroptosis resistance in osteosarcoma by inhibiting ACSF2 deubiquitination.
Yin P, Tang M, Zhao G. Yin P, et al. Mol Carcinog. 2024 Nov;63(11):2103-2118. doi: 10.1002/mc.23796. Epub 2024 Jul 23. Mol Carcinog. 2024. PMID: 39041949
The aim of this study was to investigate the regulatory mechanisms of M2 macrophage exosomes (M2-Exos) in ferroptosis in OS. A mouse model was established to investigate the in vivo role of M2-Exos. ...Apoc1 was highly expressed in M2-Exos, and interfe …
The aim of this study was to investigate the regulatory mechanisms of M2 macrophage exosomes (M2-Exos) in ferroptosis in OS. A …
FGF21-loaded M2 macrophage-derived exosomes attenuate sepsis-induced lung injury by regulating M2 macrophage polarization and glycolysis.
Wu F, Zhang Y, Tang Y, Kang Y, Li Y, Hu X, Liu J, Tian X, Lu Z. Wu F, et al. Life Sci. 2025 Nov 1;380:123932. doi: 10.1016/j.lfs.2025.123932. Epub 2025 Aug 30. Life Sci. 2025. PMID: 40889696 Free article.
However, the short half-life (t ) of FGF21 limits its clinical application. In this study, we designed FGF21-loaded M2 macrophage-derived exosomes, named FGF21-M2-Exos, for the treatment of sepsis-induced ALI. We demonstrated that FGF21-M2-Exos were able to r …
However, the short half-life (t ) of FGF21 limits its clinical application. In this study, we designed FGF21-loaded M2 macrophage-der …
Dissection of pro-tumoral macrophage subtypes and immunosuppressive cells participating in M2 polarization.
Sezginer O, Unver N. Sezginer O, et al. Inflamm Res. 2024 Sep;73(9):1411-1423. doi: 10.1007/s00011-024-01907-3. Epub 2024 Jun 27. Inflamm Res. 2024. PMID: 38935134 Free PMC article. Review.
Treg cells selectively support the metabolic stability, mitochondrial integrity, and survival rate of M2-like TAMs in an indirect environment. Also, the contribution of Breg cells influences macrophage polarization towards the M2 direction. ...In this review, we hav …
Treg cells selectively support the metabolic stability, mitochondrial integrity, and survival rate of M2-like TAMs in an indirect env …
209,318 results
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