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Natural compounds regulate the PI3K/Akt/GSK3β pathway in myocardial ischemia-reperfusion injury.
Ajzashokouhi AH, Rezaee R, Omidkhoda N, Karimi G. Ajzashokouhi AH, et al. Cell Cycle. 2023 Apr;22(7):741-757. doi: 10.1080/15384101.2022.2161959. Epub 2023 Jan 2. Cell Cycle. 2023. PMID: 36593695 Free PMC article.
The present article discusses the involvement of the PI3K/Akt/GSK3beta pathway in cardioprotective effects of natural products against MIRI.Abbreviations: Akt: protein kinase B; AMPK: AMP-activated protein kinase; ATP: adenosine triphosphate; Bad: bcl2-associated agonist of cell …
The present article discusses the involvement of the PI3K/Akt/GSK3beta pathway in cardioprotective effects of natural products against MIRI. …
Combined effects of pioglitazone and doxorubicin on migration and invasion of MDA-MB-231 breast cancer cells.
Malakouti P, Mohammadi M, Boshagh MA, Amini A, Rezaee MA, Rahmani MR. Malakouti P, et al. J Egypt Natl Canc Inst. 2022 Mar 28;34(1):13. doi: 10.1186/s43046-022-00110-x. J Egypt Natl Canc Inst. 2022. PMID: 35342925
METHODS: In this research, we evaluated the anti-invasive property of pioglitazone along with antitumor effects of doxorubicin on MDA-MB-231 breast cancer cell lines. RESULTS: There was no significant difference between two treatment groups in neither the expression nor ch …
METHODS: In this research, we evaluated the anti-invasive property of pioglitazone along with antitumor effects of doxorubicin on MDA-MB …
Curcumin for the prevention of myocardial injury following elective percutaneous coronary intervention; a pilot randomized clinical trial.
Aslanabadi N, Entezari-Maleki T, Rezaee H, Jafarzadeh HR, Vahedpour R. Aslanabadi N, et al. Eur J Pharmacol. 2019 Sep 5;858:172471. doi: 10.1016/j.ejphar.2019.172471. Epub 2019 Jun 19. Eur J Pharmacol. 2019. PMID: 31228455 Clinical Trial.
The results showed that the raise of CK-MB in curcumin group was half of the control group (4 vs. 8 cases) but was not significant. There were no significant differences in CK-MB levels at 8 (P = .24) and 24 h (P = .37) after PCI between the curcumin and the control …
The results showed that the raise of CK-MB in curcumin group was half of the control group (4 vs. 8 cases) but was not significant. T …