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Year Number of Results
1992 1
2008 2
2009 2
2010 1
2011 3
2012 1
2019 1
2020 1
2022 0
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11 results
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Page 1
Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors.
Balmanoukian AS, Infante JR, Aljumaily R, Naing A, Chintakuntlawar AV, Rizvi NA, Ross HJ, Gordon M, Mallinder PR, Elgeioushi N, González-García I, Standifer N, Cann J, Durham N, Rahimian S, Kumar R, Denlinger CS. Balmanoukian AS, et al. Among authors: mallinder pr. Clin Cancer Res. 2020 Dec 1;26(23):6196-6203. doi: 10.1158/1078-0432.CCR-20-0452. Epub 2020 Sep 4. Clin Cancer Res. 2020. PMID: 32887725 Clinical Trial.
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Vousden KA, Lundqvist T, Popovic B, Naiman B, Carruthers AM, Newton P, Johnson DJD, Pomowski A, Wilkinson T, Dufner P, de Mendez I, Mallinder PR, Murray C, Strain M, Connor J, Murray LA, Sleeman MA, Lowe DC, Huntington JA, Vaughan TJ. Vousden KA, et al. Among authors: mallinder pr. Sci Rep. 2019 Feb 7;9(1):1605. doi: 10.1038/s41598-019-38842-x. Sci Rep. 2019. PMID: 30733557 Free PMC article.
Identification of iNOS inhibitors using InteraX.
Mallinder PR, Wallace AV, Allenby G. Mallinder PR, et al. J Biomol Screen. 2009 Mar;14(3):263-72. doi: 10.1177/1087057109331476. Epub 2009 Feb 11. J Biomol Screen. 2009. PMID: 19211775
Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokinetics.
Finch DK, Sleeman MA, Moisan J, Ferraro F, Botterell S, Campbell J, Cochrane D, Cruwys S, England E, Lane S, Rendall E, Sinha M, Walker C, Rees G, Bowen MA, Schneider A, Liang M, Faggioni R, Fung M, Mallinder PR, Wilkinson T, Kolbeck R, Vaughan T, Lowe DC. Finch DK, et al. Among authors: mallinder pr. J Mol Biol. 2011 Aug 26;411(4):791-807. doi: 10.1016/j.jmb.2011.06.031. Epub 2011 Jun 23. J Mol Biol. 2011. PMID: 21723291
E. coli expression and purification of human and cynomolgus IL-15.
Ward A, Anderson M, Craggs RI, Maltby J, Grahames C, Davies RA, Finch D, Pattison D, Oakes H, Mallinder PR. Ward A, et al. Among authors: mallinder pr. Protein Expr Purif. 2009 Nov;68(1):42-8. doi: 10.1016/j.pep.2009.05.004. Epub 2009 May 10. Protein Expr Purif. 2009. PMID: 19435602
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Garcin ED, Arvai AS, Rosenfeld RJ, Kroeger MD, Crane BR, Andersson G, Andrews G, Hamley PJ, Mallinder PR, Nicholls DJ, St-Gallay SA, Tinker AC, Gensmantel NP, Mete A, Cheshire DR, Connolly S, Stuehr DJ, Aberg A, Wallace AV, Tainer JA, Getzoff ED. Garcin ED, et al. Among authors: mallinder pr. Nat Chem Biol. 2008 Nov;4(11):700-7. doi: 10.1038/nchembio.115. Epub 2008 Oct 12. Nat Chem Biol. 2008. PMID: 18849972 Free PMC article.
Engineering a high-affinity anti-IL-15 antibody: crystal structure reveals an α-helix in VH CDR3 as key component of paratope.
Lowe DC, Gerhardt S, Ward A, Hargreaves D, Anderson M, Ferraro F, Pauptit RA, Pattison DV, Buchanan C, Popovic B, Finch DK, Wilkinson T, Sleeman M, Vaughan TJ, Mallinder PR. Lowe DC, et al. Among authors: mallinder pr. J Mol Biol. 2011 Feb 11;406(1):160-75. doi: 10.1016/j.jmb.2010.12.017. Epub 2010 Dec 16. J Mol Biol. 2011. PMID: 21167836
11 results