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Antigen Presentation by Vascular Cells.

Pober JS, Merola J, Liu R, Manes TD. Pober JS, et al. Among authors: manes td. Front Immunol. 2017 Dec 22;8:1907. doi: 10.3389/fimmu.2017.01907. eCollection 2017. Front Immunol. 2017. PMID: 29312357 Free PMC article. Review.

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ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.

Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Fang C, et al. Among authors: manes td. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. Nat Commun. 2019. PMID: 31113953 Free PMC article.

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Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.

Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. Merola J, et al. Among authors: manes td. JCI Insight. 2019 Oct 17;4(20):e129739. doi: 10.1172/jci.insight.129739. JCI Insight. 2019. PMID: 31527312 Free PMC article.

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Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1.

Liu R, Merola J, Manes TD, Qin L, Tietjen GT, López-Giráldez F, Broecker V, Fang C, Xie C, Chen PM, Kirkiles-Smith NC, Jane-Wit D, Pober JS. Liu R, et al. Among authors: manes td. JCI Insight. 2018 Mar 8;3(5):e97881. doi: 10.1172/jci.insight.97881. JCI Insight. 2018. PMID: 29515027 Free PMC article.

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αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression.

Dutta A, Li J, Fedele C, Sayeed A, Singh A, Violette SM, Manes TD, Languino LR. Dutta A, et al. Among authors: manes td. Biochem J. 2015 Mar 15;466(3):525-36. doi: 10.1042/BJ20140698. Biochem J. 2015. PMID: 25558779 Free PMC article.

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Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells.

Manes TD, Wang V, Pober JS. Manes TD, et al. J Immunol. 2018 Dec 1;201(11):3167-3174. doi: 10.4049/jimmunol.1800223. Epub 2018 Oct 19. J Immunol. 2018. PMID: 30341183 Free PMC article.

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Significant Differences in Antigen-Induced Transendothelial Migration of Human CD8 and CD4 T Effector Memory Cells.

Manes TD, Pober JS. Manes TD, et al. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1910-8. doi: 10.1161/ATVBAHA.116.308039. Epub 2016 Jul 21. Arterioscler Thromb Vasc Biol. 2016. PMID: 27444200 Free PMC article.

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Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2.

Wang C, Qin L, Manes TD, Kirkiles-Smith NC, Tellides G, Pober JS. Wang C, et al. Among authors: manes td. J Exp Med. 2014 Mar 10;211(3):395-404. doi: 10.1084/jem.20131125. Epub 2014 Feb 10. J Exp Med. 2014. PMID: 24516119 Free PMC article.

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Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation.

Di Lorenzo A, Manes TD, Davalos A, Wright PL, Sessa WC. Di Lorenzo A, et al. Among authors: manes td. Blood. 2011 Feb 17;117(7):2284-95. doi: 10.1182/blood-2010-04-281956. Epub 2010 Dec 23. Blood. 2011. PMID: 21183689 Free PMC article.

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Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes.

Jane-wit D, Surovtseva YV, Qin L, Li G, Liu R, Clark P, Manes TD, Wang C, Kashgarian M, Kirkiles-Smith NC, Tellides G, Pober JS. Jane-wit D, et al. Among authors: manes td. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9686-91. doi: 10.1073/pnas.1503535112. Epub 2015 Jul 20. Proc Natl Acad Sci U S A. 2015. PMID: 26195760 Free PMC article.

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