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Thrombin-like serine protease, antiquorin from Euphorbia antiquorum latex induces platelet aggregation via PAR1-Akt/p38 signaling axis.
Urs AP, Manjuprasanna VN, Rudresha GV, Hiremath V, Sharanappa P, Rajaiah R, Vishwanath BS. Urs AP, et al. Among authors: manjuprasanna vn. Biochim Biophys Acta Mol Cell Res. 2021 Mar;1868(3):118925. doi: 10.1016/j.bbamcr.2020.118925. Epub 2020 Dec 14. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33333088 Free article.
Inhibition of sPLA2 enzyme activity by cell-permeable antioxidant EUK-8 and downregulation of p38, Akt, and p65 signals induced by sPLA2 in inflammatory mouse paw edema model.
Jayachandra K, Gowda MDM, Rudresha GV, Manjuprasanna VN, Urs AP, Nandana MB, Bharatha M, Jameel NM, Vishwanath BS. Jayachandra K, et al. Among authors: manjuprasanna vn. J Cell Biochem. 2023 Feb;124(2):294-307. doi: 10.1002/jcb.30366. Epub 2022 Dec 31. J Cell Biochem. 2023. PMID: 36585945
Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram).
Rudresha GV, Urs AP, Manjuprasanna VN, Milan Gowda MD, Jayachandra K, Rajaiah R, Vishwanath BS. Rudresha GV, et al. Among authors: manjuprasanna vn. PLoS Negl Trop Dis. 2021 Feb 2;15(2):e0008596. doi: 10.1371/journal.pntd.0008596. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33529194 Free PMC article.
Syringol isolated from Eleusine coracana (L.) Gaertn bran suppresses inflammatory response through the down-regulation of cPLA2, COX-2, IκBα, p38 and MPO signaling in sPLA2 induced mice paw oedema.
Milan Gowda MD, Jayachandra K, Joshi V, Manjuprasanna VN, Rudresha GV, Velmurugan D, Pachaiappan R, Jameel NM, Vishwanath BS. Milan Gowda MD, et al. Among authors: manjuprasanna vn. Inflammopharmacology. 2022 Oct;30(5):1853-1870. doi: 10.1007/s10787-022-00983-3. Epub 2022 May 31. Inflammopharmacology. 2022. PMID: 35639234
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