Mannens G[au] - Search Results

Year	Number of Results
1986	1
1988	1
1990	2
1991	1
1993	1
1994	3
1995	2
1996	1
2001	1
2002	3
2003	3
2004	1
2005	3
2006	1
2007	2
2008	3
2009	3
2011	3
2012	2
2013	2
2014	2
2015	4
2016	2
2017	2
2019	1
2021	1
2022	2

1

Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity.

Brehmer D, Beke L, Wu T, Millar HJ, Moy C, Sun W, Mannens G, Pande V, Boeckx A, van Heerde E, Nys T, Gustin EM, Verbist B, Zhou L, Fan Y, Bhargava V, Safabakhsh P, Vinken P, Verhulst T, Gilbert A, Rai S, Graubert TA, Pastore F, Fiore D, Gu J, Johnson A, Philippar U, Morschhäuser B, Walker D, De Lange D, Keersmaekers V, Viellevoye M, Diels G, Schepens W, Thuring JW, Meerpoel L, Packman K, Lorenzi MV, Laquerre S. Brehmer D, et al. Among authors: mannens g. Mol Cancer Ther. 2021 Dec;20(12):2317-2328. doi: 10.1158/1535-7163.MCT-21-0367. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583982

2

Toxicokinetics and metabolism.

Coecke S, Blaauboer BJ, Elaut G, Freeman S, Freidig A, Gensmantel N, Hoet P, Kapoulas VM, Ladstetter B, Langley G, Leahy D, Mannens G, Meneguz A, Monshouwer M, Nemery B, Pelkonen O, Pfaller W, Prieto P, Proctor N, Rogiers V, Rostami-Hodjegan A, Sabbioni E, Steiling W, van de Sandt JJ. Coecke S, et al. Among authors: mannens g. Altern Lab Anim. 2005 Jul;33 Suppl 1:147-75. doi: 10.1177/026119290503301s15. Altern Lab Anim. 2005. PMID: 16194147 No abstract available.

3

Cell-based models to study hepatic drug metabolism and enzyme induction in humans.

Vermeir M, Annaert P, Mamidi RN, Roymans D, Meuldermans W, Mannens G. Vermeir M, et al. Among authors: mannens g. Expert Opin Drug Metab Toxicol. 2005 Jun;1(1):75-90. doi: 10.1517/17425255.1.1.75. Expert Opin Drug Metab Toxicol. 2005. PMID: 16922654 Review.

4

Strategies for absorption screening in drug discovery and development.

Bohets H, Annaert P, Mannens G, Van Beijsterveldt L, Anciaux K, Verboven P, Meuldermans W, Lavrijsen K. Bohets H, et al. Among authors: mannens g. Curr Top Med Chem. 2001 Nov;1(5):367-83. doi: 10.2174/1568026013394886. Curr Top Med Chem. 2001. PMID: 11899103 Review.

5

Which human metabolites have we MIST? Retrospective analysis, practical aspects, and perspectives for metabolite identification and quantification in pharmaceutical development.

Leclercq L, Cuyckens F, Mannens GS, de Vries R, Timmerman P, Evans DC. Leclercq L, et al. Among authors: mannens gs. Chem Res Toxicol. 2009 Feb;22(2):280-93. doi: 10.1021/tx800432c. Chem Res Toxicol. 2009. PMID: 19183054 Review.

6

Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes.

de Vries R, Jacobs F, Mannens G, Snoeys J, Cuyckens F, Chien C, Ward P. de Vries R, et al. Among authors: mannens g. Drug Metab Dispos. 2019 May;47(5):453-464. doi: 10.1124/dmd.118.084517. Epub 2019 Feb 20. Drug Metab Dispos. 2019. PMID: 30787101 Clinical Trial.

7

Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.

Chen G, Mannens G, De Boeck M, Daly EJ, Canuso CM, Teuns G, Manji H, Drevets WC. Chen G, et al. Among authors: mannens g. Mol Psychiatry. 2022 Apr;27(4):1860-1862. doi: 10.1038/s41380-022-01447-4. Epub 2022 Feb 17. Mol Psychiatry. 2022. PMID: 35177823 Free PMC article. No abstract available.

8

Evaluation of the Pharmacokinetics and Renal Excretion of Simeprevir in Subjects with Renal Impairment.

Ouwerkerk-Mahadevan S, Beumont-Mauviel M, Mortier S, Peeters M, Verloes R, Truyers C, Mannens G, Wynant I, Simion A. Ouwerkerk-Mahadevan S, et al. Among authors: mannens g. Drugs R D. 2015 Sep;15(3):261-70. doi: 10.1007/s40268-015-0101-0. Drugs R D. 2015. PMID: 26248593 Free PMC article. Clinical Trial.

9

Best practices for metabolite quantification in drug development: updated recommendation from the European Bioanalysis Forum.

Timmerman P, Blech S, White S, Green M, Delatour C, McDougall S, Mannens G, Smeraglia J, Williams S, Young G. Timmerman P, et al. Among authors: mannens g. Bioanalysis. 2016 Jun;8(12):1297-305. doi: 10.4155/bio-2016-0103. Epub 2016 May 24. Bioanalysis. 2016. PMID: 27217058 Free article.

10

Physiology-based IVIVE predictions of tramadol from in vitro metabolism data.

T'jollyn H, Snoeys J, Colin P, Van Bocxlaer J, Annaert P, Cuyckens F, Vermeulen A, Van Peer A, Allegaert K, Mannens G, Boussery K. T'jollyn H, et al. Among authors: mannens g. Pharm Res. 2015 Jan;32(1):260-74. doi: 10.1007/s11095-014-1460-x. Epub 2014 Jul 22. Pharm Res. 2015. PMID: 25048637

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